scholarly article | Q13442814 |
P2093 | author name string | T J Kunicki | |
S Honda | |||
Y Honda | |||
Y Tomiyama | |||
D Annis | |||
A J Pelletier | |||
R Orchekowski | |||
Z Ruggeri | |||
P2860 | cites work | T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1 | Q24296288 |
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation | Q24337851 | ||
A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples | Q29615292 | ||
Two human monoclonal antiplatelet autoantibodies established from patients with chronic idiopathic thrombocytopenic purpura | Q33372545 | ||
Localization of human platelet autoantigens to the cysteine-rich region of glycoprotein IIIa | Q33373533 | ||
Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function | Q34353018 | ||
A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex | Q34541247 | ||
Divalent cation regulation of the surface orientation of platelet membrane glycoprotein IIb. Correlation with fibrinogen binding function and definition of a novel variant of Glanzmann's thrombasthenia | Q34543964 | ||
Human platelet Fc receptor for immunoglobulin G. Identification as a 40,000-molecular-weight membrane protein shared by monocytes | Q34569646 | ||
Platelet-collagen adhesion: inhibition by a monoclonal antibody that binds glycoprotein IIb. | Q36212080 | ||
An immunologic approach to the conformational equilibria of polypeptides | Q37504019 | ||
The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets | Q37556824 | ||
GPIIb-IIIa: the responsive integrin | Q37699902 | ||
A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation | Q38339624 | ||
The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering | Q41517769 | ||
Fibronectin expression on the platelet surface occurs in concert with secretion | Q41631064 | ||
Regulation of the VLA integrin-ligand interactions through the beta 1 subunit | Q41909450 | ||
Cell-surface regulation of beta 1-integrin activity on developing retinal neurons | Q42260840 | ||
Assignment of disulphide bonds in human platelet GPIIIa. A disulphide pattern for the beta-subunits of the integrin family | Q42860255 | ||
A monoclonal antibody to beta 1 integrin (CD29) stimulates VLA-dependent adherence of leukocytes to human umbilical vein endothelial cells and matrix components | Q43108177 | ||
Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor | Q46057359 | ||
Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins | Q48345069 | ||
Antibody production in baculovirus-infected insect cells | Q52441844 | ||
Human monoclonal autoantibody 2E7 is specific for a peptide sequence of platelet glycoprotein IIb. Localization of the epitope to IIb231-238 with an immunodominant Trp235 | Q67700503 | ||
Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding | Q71655421 | ||
P4510 | describes a project that uses | AP-5 | Q54750187 |
P433 | issue | 20 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell line | Q21014462 |
P304 | page(s) | 11947-11954 | |
P577 | publication date | 1995-05-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit | |
P478 | volume | 270 |
Q45099239 | A 50-A separation of the integrin alpha v beta 3 extracellular domain C termini reveals an intermediate activation state |
Q39434031 | A mutation in the β3 cytoplasmic tail causes variant Glanzmann thrombasthenia by abrogating transition of αIIb β3 to an active state |
Q33391496 | A new Ser472Asn (Cab2(a+)) polymorphism localized within the αIIb "thigh" domain is involved in neonatal thrombocytopenia |
Q24300709 | A novel adaptation of the integrin PSI domain revealed from its crystal structure |
Q51052050 | A novel role of angiopoietin-like-3 associated with podocyte injury. |
Q46050405 | A redox site involved in integrin activation |
Q37387501 | A two-amino acid insertion in the Cys146- Cys167 loop of the alphaIIb subunit is associated with a variant of Glanzmann thrombasthenia. Critical role of Asp163 in ligand binding |
Q41238021 | Activation of the integrin alpha v beta 3 involves a discrete cation-binding site that regulates conformation |
Q33426085 | Alloantibody against new platelet alloantigen (Lap(a)) on glycoprotein IIb is responsible for a case of fetal and neonatal alloimmune thrombocytopenia |
Q41670605 | AlphaVBeta3 Integrin expression within uterine endometrium in unexplained infertility: a prospective cohort study |
Q30355763 | Alterations in immunodominance of Streptococcus mutans AgI/II: lessons learned from immunomodulatory antibodies |
Q33400668 | Antibodies causing thrombocytopenia in patients treated with RGD-mimetic platelet inhibitors recognize ligand-specific conformers of αIIb/β3 integrin |
Q36407213 | Application of high-throughput screening to identify a novel alphaIIb-specific small- molecule inhibitor of alphaIIbbeta3-mediated platelet interaction with fibrinogen. |
Q41710125 | Are changes in integrin affinity and conformation overemphasized? |
Q33333577 | Autoantibodies and autoantigens in chronic immune thrombocytopenic purpura |
Q49095625 | CD4+ T lymphocytes migrating in three-dimensional collagen lattices lack focal adhesions and utilize beta1 integrin-independent strategies for polarization, interaction with collagen fibers and locomotion |
Q33872298 | Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis |
Q73879359 | Classification of 'activation' antibodies against integrin beta1 chain |
Q49814920 | Clinical Relevance of Histopathologic Analysis of HeartMate II Thrombi |
Q90647950 | Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension |
Q27657149 | Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment |
Q98237793 | Dissection of α4β7 integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β7 antibodies |
Q41050898 | Divalent cations and ligands induce conformational changes that are highly divergent among beta1 integrins |
Q41959709 | Down-regulation of alpha v/beta 3 integrin via misrouting to lysosomes by overexpression of a beta 3Lamp1 fusion protein |
Q64093750 | Effect of αvβ3 Integrin Expression and Activity on Intraocular Pressure |
Q33885186 | Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3. |
Q74453396 | Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma |
Q42542148 | Evidence that monoclonal antibodies directed against the integrin beta subunit plexin/semaphorin/integrin domain stimulate function by inducing receptor extension. |
Q57726936 | Experimental concerns regarding suPAR-related proteinuria |
Q74551398 | Expression of ligand-induced binding sites on glycoprotein IIb/IIIa complexes and the effect of various inhibitors |
Q45099923 | Fibrinogen receptor antagonists induce conformational changes of the human platelet glycoprotein IIb. |
Q33377139 | Fine specificity of drug-dependent antibodies reactive with a restricted domain of platelet GPIIIA |
Q37215081 | Functional and computational studies of the ligand-associated metal binding site of beta3 integrins |
Q39592588 | High-efficiency utilization of the bovine integrin alpha(v)beta(3) as a receptor for foot-and-mouth disease virus is dependent on the bovine beta(3) subunit |
Q42437087 | Human neutrophil elastase proteolytically activates the platelet integrin alphaIIbbeta3 through cleavage of the carboxyl terminus of the alphaIIb subunit heavy chain. Involvement in the potentiation of platelet aggregation |
Q41728094 | Identification of amino acid sequences in fibrinogen gamma -chain and tenascin C C-terminal domains critical for binding to integrin alpha vbeta 3. |
Q42249278 | Immunological characterization of eristostatin and echistatin binding sites on alpha IIb beta 3 and alpha V beta 3 integrins |
Q35762202 | Inhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3. |
Q34731123 | Insights into integrin-ligand binding and activation from the first crystal structure. |
Q35266840 | Intact alphaIIbbeta3 integrin is extended after activation as measured by solution X-ray scattering and electron microscopy |
Q30848202 | Integrin activation and structural rearrangement |
Q41045839 | Integrin activation by dithiothreitol or Mn2+ induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the beta1 integrin chain |
Q40924680 | Integrin activation: the link between ligand binding and signal transduction |
Q30485323 | Integrin alpha IIb beta 3 in a membrane environment remains the same height after Mn2+ activation when observed by cryoelectron tomography |
Q36564206 | Integrin structures and conformational signaling |
Q35181671 | Integrins, cations and ligands: making the connection |
Q41307237 | Integrins: role in cell adhesion and communication |
Q37810633 | Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation |
Q28189326 | Intrinsic activating properties of GP IIb/IIIa blockers |
Q28216733 | Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3 |
Q30479586 | Ligand density dramatically affects integrin alpha IIb beta 3-mediated platelet signaling and spreading |
Q38611243 | Low affinity binding in cis to P2Y2R mediates force-dependent integrin activation during hantavirus infection |
Q35804502 | Mapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation |
Q38399145 | Matched rabbit monoclonal antibodies against αv-series integrins reveal a novel αvβ3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors |
Q46465757 | Membrane-proximal {alpha}/{beta} stalk interactions differentially regulate integrin activation |
Q53510545 | Modification of kidney barrier function by the urokinase receptor. |
Q34236673 | Modulation of integrin activation by an entropic spring in the {beta}-knee |
Q57591551 | Molecular Dynamics Reveal that isoDGR-Containing Cyclopeptides Are True αvβ3 Antagonists Unable To Promote Integrin Allostery and Activation |
Q57953602 | Molecular Dynamics Reveal that isoDGR-Containing Cyclopeptides Are True αvβ3 Antagonists Unable To Promote Integrin Allostery and Activation |
Q33497352 | Molecular identification of T cells that respond in a primary bulk culture to a peptide derived from a platelet glycoprotein implicated in neonatal alloimmune thrombocytopenia |
Q46520681 | Molecular requirements for assembly and function of a minimized human integrin alphaIIbbeta3. |
Q60044375 | Monitoring suPAR levels in post-kidney transplant focal segmental glomerulosclerosis treated with therapeutic plasma exchange and rituximab |
Q71823689 | Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium |
Q38957041 | Natural and artificial mutations in αIIb integrin lead to a structural deformation of a calcium-binding site |
Q33925042 | Osteoclast motility: putting the brakes on bone resorption. |
Q34496409 | Platelet integrin alphaIIbbeta3-ligand interactions: what can we learn from the structure? |
Q34378163 | Post-translational modifications of recombinant P-selectin glycoprotein ligand-1 required for binding to P- and E-selectin |
Q41723052 | Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3). |
Q40785864 | Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation |
Q37358903 | Rapid parallel flow cytometry assays of active GTPases using effector beads |
Q43188550 | Rationally designed integrin beta3 mutants stabilized in the high affinity conformation |
Q36987307 | Recurrent Primary Focal Segmental Glomerulosclerosis Managed With Intensified Plasma Exchange and Concomitant Monitoring of Soluble Urokinase-Type Plasminogen Activator Receptor-Mediated Podocyte β3-integrin Activation |
Q46599137 | Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain |
Q34805673 | Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand |
Q24292863 | Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectin |
Q29617618 | Structural basis of integrin regulation and signaling |
Q28256775 | Structural basis of integrin-mediated signal transduction |
Q27653293 | Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces |
Q90292261 | Structure of an extended β3 integrin |
Q27678064 | Structure-Guided Design of a High-Affinity Platelet Integrin IIb 3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS |
Q92823906 | Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis |
Q27301036 | Swing-out of the β3 hybrid domain is required for αIIbβ3 priming and normal cytoskeletal reorganization, but not adhesion to immobilized fibrinogen |
Q52624737 | TNFα pathway blockade ameliorates toxic effects of FSGS plasma on podocyte cytoskeleton and β3 integrin activation. |
Q36580090 | Targeting integrin structure and function in disease |
Q35951243 | Tests of the extension and deadbolt models of integrin activation |
Q33381441 | The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend |
Q58058035 | The Molecular Anatomy of Integrins |
Q30997990 | The N-terminal region and the mid-region complex of the integrin beta 2 subunit |
Q47438165 | The activated conformation of integrin β7 is a novel multiple myeloma-specific target for CAR T cell therapy |
Q41323508 | The activation state of the integrin alpha IIb beta 3 affects outside-in signals leading to cell spreading and focal adhesion kinase phosphorylation |
Q46427663 | The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy |
Q77746414 | The role of the cysteine-rich region of the beta2 integrin subunit in the leukocyte function-associated antigen-1 (LFA-1, alphaLbeta2, CD11a/CD18) heterodimer formation and ligand binding |
Q89777927 | αIIbβ3 binding to a fibrinogen fragment lacking the γ-chain dodecapeptide is activation dependent and EDTA inducible |
Q54750187 | AP-5 | described by source | P1343 |
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