scholarly article | Q13442814 |
P50 | author | Devon M. Fitzgerald | Q51419117 |
P2093 | author name string | P J Hastings | |
Susan M Rosenberg | |||
P2860 | cites work | Identity and function of a large gene network underlying mutagenic repair of DNA breaks | Q42969505 |
Large-Scale Chromosomal Changes and Associated Fitness Consequences in Pathogenic Fungi | Q43144415 | ||
Stress-induced mutagenesis in bacteria | Q44459277 | ||
Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappa. | Q47614597 | ||
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. | Q47673689 | ||
HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression. | Q47829016 | ||
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. | Q47991885 | ||
DNA polymerase kappa, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancer | Q49230797 | ||
Adaptive amplification: an inducible chromosomal instability mechanism | Q50117945 | ||
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. | Q50649984 | ||
Stress-induced mutagenesis and complex adaptation. | Q51052567 | ||
Mutational signatures indicative of environmental stress in bacteria. | Q53158429 | ||
A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation. | Q54478818 | ||
Adaptive mutation by deletions in small mononucleotide repeats. | Q54630365 | ||
Recombination in adaptive mutation. | Q54635736 | ||
A unicorn in the garden | Q59085860 | ||
Ultraviolet mutagenesis in polA and UvrA polA derivatives of Escherichia coli B-R: evidence for an inducible error-prone repair system | Q69269848 | ||
Gene amplification in the lac region of E. coli | Q70212173 | ||
Starvation-induced Mucts62-mediated coding sequence fusion: a role for ClpXP, Lon, RpoS and Crp | Q77410696 | ||
Is there a link between mutation rates and the stringent response in Bacillus subtilis? | Q78026711 | ||
Acceleration of emergence of bacterial antibiotic resistance in connected microenvironments | Q84975610 | ||
Inhibition of mutation and combating the evolution of antibiotic resistance | Q21146100 | ||
Independent functions of viral protein and nucleic acid in growth of bacteriophage | Q22066151 | ||
STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES: INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III | Q22066172 | ||
The replication of DNA in Escherichia coli | Q22066208 | ||
Substantial contribution of extrinsic risk factors to cancer development | Q22251076 | ||
Mutations of Bacteria from Virus Sensitivity to Virus Resistance | Q24533278 | ||
Conserved domains in DNA repair proteins and evolution of repair systems | Q24548678 | ||
Evolution of the mutation rate | Q24602069 | ||
Mutational processes molding the genomes of 21 breast cancers | Q24620915 | ||
Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis | Q24625342 | ||
Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions | Q26261171 | ||
Evolution of the cancer genome | Q27020991 | ||
A genetic model for colorectal tumorigenesis | Q27860582 | ||
Genetic instabilities in human cancers | Q28131826 | ||
SOS Repair Hypothesis: Phenomenology of an Inducible DNA Repair Which is Accompanied by Mutagenesis | Q28141658 | ||
Evolution of mutation rates in bacteria | Q28238561 | ||
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer | Q28256988 | ||
Mechanisms and functions of DNA mismatch repair | Q28262719 | ||
Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons | Q28269868 | ||
The clonal evolution of tumor cell populations | Q28271546 | ||
Deciphering signatures of mutational processes operative in human cancer | Q28283300 | ||
DNA topoisomerases and their poisoning by anticancer and antibacterial drugs | Q28284744 | ||
The yeast environmental stress response regulates mutagenesis induced by proteotoxic stress | Q28535023 | ||
DNA polymerase kappa deficiency does not affect somatic hypermutation in mice | Q28587758 | ||
Tumour evolution inferred by single-cell sequencing | Q28646966 | ||
Clonal evolution in cancer | Q29547696 | ||
DNA polymerases are error-prone at RecA-mediated recombination intermediates. | Q37396897 | ||
Contribution of the mismatch DNA repair system to the generation of stationary-phase-induced mutants of Bacillus subtilis | Q37513635 | ||
APOBEC3B is an enzymatic source of mutation in breast cancer. | Q37533713 | ||
Protein folding sculpting evolutionary change | Q37726611 | ||
Premalignant breast neoplasia: a paradigm of interlesional and intralesional molecular heterogeneity and its biological and clinical ramifications | Q37737866 | ||
Stress-induced modulators of repeat instability and genome evolution | Q37976153 | ||
The impact of transposable elements in environmental adaptation. | Q38072072 | ||
Tumor hypoxia as a driving force in genetic instability. | Q38155002 | ||
Microbiological effects of sublethal levels of antibiotics. | Q38214805 | ||
Cancer: evolution within a lifetime | Q38257835 | ||
Suppression of mTOR pathway in solid tumors: lessons learned from clinical experience in renal cell carcinoma and neuroendocrine tumors and new perspectives. | Q38527936 | ||
Repair of DNA damage induced by bile salts in Salmonella enterica | Q38583344 | ||
R loops: new modulators of genome dynamics and function | Q38586926 | ||
Mechanisms and Consequences of Cancer Genome Instability: Lessons from Genome Sequencing Studies. | Q38747173 | ||
Hsp90: A Global Regulator of the Genotype-to-Phenotype Map in Cancers | Q38750437 | ||
Involvement of sigma(S) in starvation-induced transposition of Pseudomonas putida transposon Tn4652. | Q39504849 | ||
Redox-responsive zinc finger fidelity switch in homing endonuclease and intron promiscuity in oxidative stress | Q39710107 | ||
Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells | Q39745939 | ||
Non-homologous end joining as an important mutagenic process in cell cycle-arrested cells | Q39756406 | ||
Analysis of cell size and DNA content in exponentially growing and stationary-phase batch cultures of Escherichia coli | Q39839306 | ||
Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max network | Q40175307 | ||
Hypoxia-inducible factor-1 mediates the expression of DNA polymerase iota in human tumor cells | Q40217073 | ||
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia | Q40227628 | ||
SOS functions, cancer and inducible evolution | Q40313397 | ||
Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. | Q40467165 | ||
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors | Q40631570 | ||
Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy | Q41000066 | ||
Transcriptional de-repression and Mfd are mutagenic in stressed Bacillus subtilis cells | Q41445233 | ||
Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runs | Q41572901 | ||
The origin of spontaneous mutation in Saccharomyces cerevisiae. | Q41616101 | ||
Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins. | Q42024219 | ||
Global regulators orchestrate group II intron retromobility | Q42105024 | ||
On the mechanism of gene amplification induced under stress in Escherichia coli | Q33239373 | ||
Mutability and importance of a hypermutable cell subpopulation that produces stress-induced mutants in Escherichia coli | Q33373675 | ||
A microhomology-mediated break-induced replication model for the origin of human copy number variation | Q33404060 | ||
Adaptive mutation sequences reproduced by mismatch repair deficiency | Q33640315 | ||
Spontaneous DNA breakage in single living Escherichia coli cells | Q33796363 | ||
Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation | Q33886793 | ||
The SOS response regulates adaptive mutation | Q33903483 | ||
Transposons, environmental changes, and heritable induced phenotypic variability. | Q33935404 | ||
Clusters of mutations from transient hypermutability | Q33943859 | ||
SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification | Q33953638 | ||
Adaptive reversion of a frameshift mutation in Escherichia coli | Q33958142 | ||
DNA synthesis errors associated with double-strand-break repair | Q33965497 | ||
A role for REV3 in mutagenesis during double-strand break repair in Saccharomyces cerevisiae | Q33971118 | ||
Medicine. Combating evolution to fight disease | Q33980301 | ||
Global chromosomal structural instability in a subpopulation of starving Escherichia coli cells | Q34013646 | ||
The sigma(E) stress response is required for stress-induced mutation and amplification in Escherichia coli | Q34017416 | ||
Clonal evolution in breast cancer revealed by single nucleus genome sequencing. | Q34041603 | ||
Separate DNA Pol II- and Pol IV-dependent pathways of stress-induced mutation during double-strand-break repair in Escherichia coli are controlled by RpoS. | Q34119281 | ||
Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions | Q34146358 | ||
The RpoS-mediated general stress response in Escherichia coli | Q34189650 | ||
The evolution of stress-induced hypermutation in asexual populations | Q34285727 | ||
Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment. | Q34300803 | ||
Homologous Recombination-Experimental Systems, Analysis, and Significance | Q34308000 | ||
Bow ties, metabolism and disease | Q34343513 | ||
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells | Q34348322 | ||
Translesion DNA polymerases | Q34356338 | ||
Evidence for APOBEC3B mutagenesis in multiple human cancers | Q34357412 | ||
Hsp90 modulates CAG repeat instability in human cells | Q34427556 | ||
Adaptive, or stationary-phase, mutagenesis, a component of bacterial differentiation in Bacillus subtilis | Q34436201 | ||
Lessons from model organisms: phenotypic robustness and missing heritability in complex disease | Q34481875 | ||
Transient and heritable mutators in adaptive evolution in the lab and in nature | Q34603730 | ||
The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness | Q34609052 | ||
Evidence that stationary-phase hypermutation in the Escherichia coli chromosome is promoted by recombination | Q34609122 | ||
General stress response regulator RpoS in adaptive mutation and amplification in Escherichia coli | Q34643555 | ||
Break-induced replication is a source of mutation clusters underlying kataegis | Q34757099 | ||
Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B | Q34782173 | ||
HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models | Q34793260 | ||
Roles of YqjH and YqjW, homologs of the Escherichia coli UmuC/DinB or Y superfamily of DNA polymerases, in stationary-phase mutagenesis and UV-induced mutagenesis of Bacillus subtilis | Q34810207 | ||
Emergence of antibiotic resistance from multinucleated bacterial filaments | Q34925901 | ||
Engineered proteins detect spontaneous DNA breakage in human and bacterial cells | Q35028595 | ||
Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coli | Q35170976 | ||
Mismatch repair protein MutL becomes limiting during stationary-phase mutation | Q35190848 | ||
Massive diversification in aging colonies of Escherichia coli | Q35198922 | ||
Double-strand-break repair recombination in Escherichia coli: physical evidence for a DNA replication mechanism in vivo | Q35208627 | ||
Environmental stress induces trinucleotide repeat mutagenesis in human cells | Q35229441 | ||
Bursts of transposable elements as an evolutionary driving force | Q35309256 | ||
Negative regulation of mutS and mutH repair gene expression by the Hfq and RpoS global regulators of Escherichia coli K-12. | Q35633546 | ||
Evolutionary significance of stress-induced mutagenesis in bacteria | Q35785631 | ||
Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I. | Q35813374 | ||
APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity | Q35836909 | ||
Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. | Q35992079 | ||
Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response | Q36030459 | ||
Mechanisms for recurrent and complex human genomic rearrangements | Q36044446 | ||
A Big Bang model of human colorectal tumor growth | Q36074227 | ||
The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers | Q36244879 | ||
Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage | Q36289433 | ||
Replication-transcription conflicts in bacteria. | Q36307709 | ||
The radiation sensitivity of Escherichia coli B: a hypothesis relating filament formation and prophage induction | Q36462785 | ||
Two mechanisms produce mutation hotspots at DNA breaks in Escherichia coli | Q36713351 | ||
β-Lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity | Q36737307 | ||
CasExpress reveals widespread and diverse patterns of cell survival of caspase-3 activation during development in vivo | Q36896412 | ||
Punctuated evolution of prostate cancer genomes | Q36950514 | ||
R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli | Q37025967 | ||
DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli | Q37173424 | ||
Bistability, epigenetics, and bet-hedging in bacteria | Q37184651 | ||
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers | Q37211712 | ||
Stress-induced beta-lactam antibiotic resistance mutation and sequences of stationary-phase mutations in the Escherichia coli chromosome. | Q37355812 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | genome instability | Q2892636 |
Kataegis | Q6374990 | ||
double-strand break repair | Q14818014 | ||
P304 | page(s) | 119-140 | |
P577 | publication date | 2017-03-01 | |
P1476 | title | Stress-Induced Mutagenesis: Implications in Cancer and Drug Resistance | |
P478 | volume | 1 |
Q36395746 | A shifting mutational landscape in 6 nutritional states: Stress-induced mutagenesis as a series of distinct stress input-mutation output relationships. |
Q64388197 | Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage |
Q90505681 | Bacterial phenotypic heterogeneity in DNA repair and mutagenesis |
Q40298095 | Driving cancer evolution. |
Q47098951 | Errors in mutagenesis and the benefit of cell-to-cell signalling in the evolution of stress-induced mutagenesis |
Q92156808 | Fibronectin in Cancer: Friend or Foe |
Q58616281 | Fitness and Genomic Consequences of Chronic Exposure to Low Levels of Copper and Nickel in Mutation Accumulation Lines |
Q61807218 | From genome integrity to cancer |
Q96609310 | Highly parallel lab evolution reveals that epistasis can curb the evolution of antibiotic resistance |
Q95300387 | Hypermutation in single-stranded DNA |
Q89782907 | Intratumor Heterogeneity and Therapy Resistance: Contributions of Dormancy, Apoptosis Reversal (Anastasis) and Cell Fusion to Disease Recurrence |
Q47351515 | Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures |
Q103806007 | Mutation-selection balance and compensatory mechanisms in tumour evolution |
Q63968578 | Mutational and non mutational adaptation of Salmonella enterica to the gall bladder |
Q93216327 | Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways |
Q47558874 | Oxygen and RNA in stress-induced mutation. |
Q92063898 | Pharmacological Effects and Toxicogenetic Impacts of Omeprazole: Genomic Instability and Cancer |
Q96303720 | Quantitative Estimation of Oxidative Stress in Cancer Tissue Cells Through Gene Expression Data Analyses |
Q89241069 | Real-time dynamics of mutagenesis reveal the chronology of DNA repair and damage tolerance responses in single cells |
Q93063783 | Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro |
Q41200966 | Stress-induced mutagenesis: Stress diversity facilitates the persistence of mutator genes |
Q37693688 | TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells. |
Q51168768 | Temperature effects on life-history trade-offs, germline maintenance and mutation rate under simulated climate warming. |
Q89697204 | The Bacillus Subtilis K-State Promotes Stationary-Phase Mutagenesis via Oxidative Damage |
Q90169803 | The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them |
Q39326888 | The Small RNA GcvB Promotes Mutagenic Break Repair by Opposing the Membrane Stress Response |
Q33778201 | The road not taken: Could stress-specific mutations lead to different evolutionary paths? |
Q57190619 | Trinucleotide Repeat Expansion Diseases, RNAi, and Cancer |
Q90043556 | Tumor Microenvironment - Selective Pressures Boosting Cancer Progression |
Q47151384 | Was the Watchmaker Blind? Or Was She One-Eyed? |
Q64096919 | What is mutation? A chapter in the series: How microbes "jeopardize" the modern synthesis |
Search more.