Stress-Induced Mutagenesis: Implications in Cancer and Drug Resistance

scientific article published on 01 March 2017

Stress-Induced Mutagenesis: Implications in Cancer and Drug Resistance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1146/ANNUREV-CANCERBIO-050216-121919
P932PMC publication ID5794033
P698PubMed publication ID29399660

P50authorDevon M. FitzgeraldQ51419117
P2093author name stringP J Hastings
Susan M Rosenberg
P2860cites workIdentity and function of a large gene network underlying mutagenic repair of DNA breaksQ42969505
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DNA polymerase kappa, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancerQ49230797
Adaptive amplification: an inducible chromosomal instability mechanismQ50117945
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.Q50649984
Stress-induced mutagenesis and complex adaptation.Q51052567
Mutational signatures indicative of environmental stress in bacteria.Q53158429
A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation.Q54478818
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STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES: INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE IIIQ22066172
The replication of DNA in Escherichia coliQ22066208
Substantial contribution of extrinsic risk factors to cancer developmentQ22251076
Mutations of Bacteria from Virus Sensitivity to Virus ResistanceQ24533278
Conserved domains in DNA repair proteins and evolution of repair systemsQ24548678
Evolution of the mutation rateQ24602069
Mutational processes molding the genomes of 21 breast cancersQ24620915
Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesisQ24625342
Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisionsQ26261171
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Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposonsQ28269868
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The yeast environmental stress response regulates mutagenesis induced by proteotoxic stressQ28535023
DNA polymerase kappa deficiency does not affect somatic hypermutation in miceQ28587758
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DNA polymerases are error-prone at RecA-mediated recombination intermediates.Q37396897
Contribution of the mismatch DNA repair system to the generation of stationary-phase-induced mutants of Bacillus subtilisQ37513635
APOBEC3B is an enzymatic source of mutation in breast cancer.Q37533713
Protein folding sculpting evolutionary changeQ37726611
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The impact of transposable elements in environmental adaptation.Q38072072
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Hsp90: A Global Regulator of the Genotype-to-Phenotype Map in CancersQ38750437
Involvement of sigma(S) in starvation-induced transposition of Pseudomonas putida transposon Tn4652.Q39504849
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Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian CellsQ39745939
Non-homologous end joining as an important mutagenic process in cell cycle-arrested cellsQ39756406
Analysis of cell size and DNA content in exponentially growing and stationary-phase batch cultures of Escherichia coliQ39839306
Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max networkQ40175307
Hypoxia-inducible factor-1 mediates the expression of DNA polymerase iota in human tumor cellsQ40217073
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxiaQ40227628
SOS functions, cancer and inducible evolutionQ40313397
Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis.Q40467165
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitorsQ40631570
Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidyQ41000066
Transcriptional de-repression and Mfd are mutagenic in stressed Bacillus subtilis cellsQ41445233
Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runsQ41572901
The origin of spontaneous mutation in Saccharomyces cerevisiae.Q41616101
Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.Q42024219
Global regulators orchestrate group II intron retromobilityQ42105024
On the mechanism of gene amplification induced under stress in Escherichia coliQ33239373
Mutability and importance of a hypermutable cell subpopulation that produces stress-induced mutants in Escherichia coliQ33373675
A microhomology-mediated break-induced replication model for the origin of human copy number variationQ33404060
Adaptive mutation sequences reproduced by mismatch repair deficiencyQ33640315
Spontaneous DNA breakage in single living Escherichia coli cellsQ33796363
Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutationQ33886793
The SOS response regulates adaptive mutationQ33903483
Transposons, environmental changes, and heritable induced phenotypic variability.Q33935404
Clusters of mutations from transient hypermutabilityQ33943859
SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplificationQ33953638
Adaptive reversion of a frameshift mutation in Escherichia coliQ33958142
DNA synthesis errors associated with double-strand-break repairQ33965497
A role for REV3 in mutagenesis during double-strand break repair in Saccharomyces cerevisiaeQ33971118
Medicine. Combating evolution to fight diseaseQ33980301
Global chromosomal structural instability in a subpopulation of starving Escherichia coli cellsQ34013646
The sigma(E) stress response is required for stress-induced mutation and amplification in Escherichia coliQ34017416
Clonal evolution in breast cancer revealed by single nucleus genome sequencing.Q34041603
Separate DNA Pol II- and Pol IV-dependent pathways of stress-induced mutation during double-strand-break repair in Escherichia coli are controlled by RpoS.Q34119281
Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctionsQ34146358
The RpoS-mediated general stress response in Escherichia coliQ34189650
The evolution of stress-induced hypermutation in asexual populationsQ34285727
Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.Q34300803
Homologous Recombination-Experimental Systems, Analysis, and SignificanceQ34308000
Bow ties, metabolism and diseaseQ34343513
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cellsQ34348322
Translesion DNA polymerasesQ34356338
Evidence for APOBEC3B mutagenesis in multiple human cancersQ34357412
Hsp90 modulates CAG repeat instability in human cellsQ34427556
Adaptive, or stationary-phase, mutagenesis, a component of bacterial differentiation in Bacillus subtilisQ34436201
Lessons from model organisms: phenotypic robustness and missing heritability in complex diseaseQ34481875
Transient and heritable mutators in adaptive evolution in the lab and in natureQ34603730
The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitnessQ34609052
Evidence that stationary-phase hypermutation in the Escherichia coli chromosome is promoted by recombinationQ34609122
General stress response regulator RpoS in adaptive mutation and amplification in Escherichia coliQ34643555
Break-induced replication is a source of mutation clusters underlying kataegisQ34757099
Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3BQ34782173
HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer modelsQ34793260
Roles of YqjH and YqjW, homologs of the Escherichia coli UmuC/DinB or Y superfamily of DNA polymerases, in stationary-phase mutagenesis and UV-induced mutagenesis of Bacillus subtilisQ34810207
Emergence of antibiotic resistance from multinucleated bacterial filamentsQ34925901
Engineered proteins detect spontaneous DNA breakage in human and bacterial cellsQ35028595
Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coliQ35170976
Mismatch repair protein MutL becomes limiting during stationary-phase mutationQ35190848
Massive diversification in aging colonies of Escherichia coliQ35198922
Double-strand-break repair recombination in Escherichia coli: physical evidence for a DNA replication mechanism in vivoQ35208627
Environmental stress induces trinucleotide repeat mutagenesis in human cellsQ35229441
Bursts of transposable elements as an evolutionary driving forceQ35309256
Negative regulation of mutS and mutH repair gene expression by the Hfq and RpoS global regulators of Escherichia coli K-12.Q35633546
Evolutionary significance of stress-induced mutagenesis in bacteriaQ35785631
Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I.Q35813374
APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and HeterogeneityQ35836909
Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.Q35992079
Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic responseQ36030459
Mechanisms for recurrent and complex human genomic rearrangementsQ36044446
A Big Bang model of human colorectal tumor growthQ36074227
The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancersQ36244879
Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular DamageQ36289433
Replication-transcription conflicts in bacteria.Q36307709
The radiation sensitivity of Escherichia coli B: a hypothesis relating filament formation and prophage inductionQ36462785
Two mechanisms produce mutation hotspots at DNA breaks in Escherichia coliQ36713351
β-Lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelityQ36737307
CasExpress reveals widespread and diverse patterns of cell survival of caspase-3 activation during development in vivoQ36896412
Punctuated evolution of prostate cancer genomesQ36950514
R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coliQ37025967
DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coliQ37173424
Bistability, epigenetics, and bet-hedging in bacteriaQ37184651
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancersQ37211712
Stress-induced beta-lactam antibiotic resistance mutation and sequences of stationary-phase mutations in the Escherichia coli chromosome.Q37355812
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectgenome instabilityQ2892636
KataegisQ6374990
double-strand break repairQ14818014
P304page(s)119-140
P577publication date2017-03-01
P1476titleStress-Induced Mutagenesis: Implications in Cancer and Drug Resistance
P478volume1

Reverse relations

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