Paul A Northcott

researcher (ORCID 0000-0002-1220-5252)

Paul A Northcott is …
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P496ORCID iD0000-0002-1220-5252

P735given namePaulQ4925623
PaulQ4925623
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

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author (P50)
Q57151364A Single-Cell Transcriptional Atlas of the Developing Murine Cerebellum
Q57804817A biobank of patient-derived pediatric brain tumor models
Q38831823A cell-based model system links chromothripsis with hyperploidy
Q45957975AT-03ATYPICAL TERATOID/RHABDOID TUMOUR IS A GENETICALLY HOMOGENEOUS BUT EPIGENETICALLY HETEROGENEOUS DISEASE THAT IS DEFINED BY SUBGROUP SPECIFIC SUPER-ENHANCERS.
Q39023964Aberrant immunostaining pattern of the CD24 glycoprotein in clinical samples and experimental models of pediatric medulloblastomas
Q36631618Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.
Q57289007Abstract 3089: (Epi)genetic profiling enables molecular re-classification of CNS-primitive neuroectodermal tumors
Q57289083Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups
Q61917646Abstract 3451: Interactions between N-myc and Sox9 promote medulloblastoma and determine cell fate decisions in cerebellar neural stem cells
Q57199717Abstracts
Q37517791Active medulloblastoma enhancers reveal subgroup-specific cellular origins
Q55463035Adult medulloblastoma comprises three major molecular variants.
Q91752198Advances in the classification of pediatric brain tumors through DNA methylation profiling: From research tool to frontline diagnostic
Q35774418An animal model of MYC-driven medulloblastoma
Q39910333An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma
Q48471843Anaplastic medulloblastoma in a child with Duchenne muscular dystrophy
Q48872957Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes
Q57141596Author Correction: The landscape of genomic alterations across childhood cancers
Q55462417Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.
Q42503619Bithalamic gliomas may be molecularly distinct from their unilateral high-grade counterparts.
Q94938041Bridging the treatment gap in infant medulloblastoma: Molecularly informed outcomes of a globally feasible regimen
Q61829341CELL BIOLOGY AND SIGNALING
Q41760694CXCR4 activation defines a new subgroup of Sonic hedgehog-driven medulloblastoma
Q55463800Calculating a cure for cancer: managing medulloblastoma MATH1-ematically.
Q48210831Cancer: Keeping it real to kill glioblastoma
Q48381540Canonical TGF-β pathway activity is a predictor of SHH-driven medulloblastoma survival and delineates putative precursors in cerebellar development
Q37719291Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme.
Q35784926Clonal selection drives genetic divergence of metastatic medulloblastoma
Q90814322Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation
Q92178889Correction to: Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials
Q34776833Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies
Q34031780Cross-species genomics matches driver mutations and cell compartments to model ependymoma
Q36585123Current concepts in the molecular genetics of pediatric brain tumors: implications for emerging therapies
Q37627692Cytogenetic prognostication within medulloblastoma subgroups
Q96585175DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma
Q28282708DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies
Q52655770DNA methylation-based classification of central nervous system tumours.
Q50063187DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma
Q38993103Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
Q104062835Deconstructing Sonic Hedgehog Medulloblastoma: Molecular Subtypes, Drivers, and Beyond
Q35896018Deep sequencing identifies IDH1 R132S mutation in adult medulloblastoma.
Q50051453Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.
Q59133452Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
Q34132926Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma
Q112722613Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth
Q24621907Dissecting the genomic complexity underlying medulloblastoma
Q35989886Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.
Q48915503Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system
Q37073617Divergent clonal selection dominates medulloblastoma at recurrence
Q38194990Duration of the pre-diagnostic interval in medulloblastoma is subgroup dependent
Q58034315EPENDYMOMA
Q45832596EPIG-04THE CHROMATIN LANDSCAPE OF MEDULLOBLASTOMA.
Q33917715Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity
Q34362028Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
Q34480576Epigenetic regulation of glial fibrillary acidic protein by DNA methylation in human malignant gliomas.
Q34240198Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
Q57082606Erratum: Corrigendum: Signatures of mutational processes in human cancer
Q37971394FISH and chips: the recipe for improved prognostication and outcomes for children with medulloblastoma.
Q55624498FORETINIB IS EFFECTIVE THERAPY FOR METASTATIC SONIC HEDGEHOG MEDULLOBLASTOMA.
Q34215755FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma
Q38940977Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
Q36296016Functional genomics identifies drivers of medulloblastoma dissemination
Q98611283Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation
Q45956799GE-07DNA METHYLATION IN MEDULLOBLASTOMA AND MOLECULAR DIAGNOSTICS OF BRAIN TUMORS.
Q57289055GE-21 * DRASTIC GENOMIC DIVERGENCE OF RECURRENT MEDULLOBLASTOMA INVALIDATES TARGETED THERAPIES DISCOVERED AT DIAGNOSIS
Q45824431GE-23ENHANCER HIJACKING ACTIVATES GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA.
Q39752244Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.
Q27852966Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition
Q34248736Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
Q38667981Genomic Analysis of Childhood Brain Tumors: Methods for Genome-Wide Discovery and Precision Medicine Become Mainstream.
Q43671177Genomic and transcriptomic analyses match medulloblastoma mouse models to their human counterparts
Q37665521Genomics of medulloblastoma: from Giemsa-banding to next-generation sequencing in 20 years
Q91971805Germline Elongator mutations in Sonic Hedgehog medulloblastoma
Q90691513Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma
Q36951069Gliomatosis cerebri in children shares molecular characteristics with other pediatric gliomas.
Q48227278HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth
Q33274578High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesis
Q37503144Hypermutation of the inactive X chromosome is a frequent event in cancer
Q55026482ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing.
Q24320317Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival
Q33633473Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma
Q41264935Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
Q38120467Intertumoral and intratumoral heterogeneity as a barrier for effective treatment of medulloblastoma.
Q42085653LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR)
Q92659630Large 1p36 Deletions Affecting Arid1a Locus Facilitate Mycn-Driven Oncogenesis in Neuroblastoma
Q60907391Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma
Q45956091MB-08MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS.
Q46354278MB-17FUNCTIONAL CHARACTERIZATION OF RECURRENTLY MUTATED NEURONAL TRANSCRIPTION FACTORS IN MEDULLOBLASTOMA.
Q46354298MB-18DYSFUNCTION OF THE CHROMATIN REMODELER Chd7 CAUSES ABNORMAL CEREBELLAR DEVELOPMENT AND ACCELERATES MEDULLOBLASTOMA FORMATION.
Q45957864MB-25REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1b.
Q46354746MB-44SUBGROUP-SPECIFIC QUANTITATIVE PROTEOMIC ANALYSIS OF MEDULLOBLASTOMA.
Q45742611MB-46PROGNOSTIC RELEVANCE OF EPIGENETIC/BIOLOGICAL SUBGROUPS AND MYCC/MYCN GENE AMPLIFICATION IN A HOMOGENOUSLY TREATED METASTATIC MEDULLOBLASTOMA HIT2000 COHORT AGED 4-21 YEARS.
Q94067925MBCL-08. MOLECULAR CHARACTERIZATION OF NODULAR DESMOPLASTIC MEDULLOBLASTOMAS IN YOUNG CHILDREN TREATED ON ACNS1221. A REPORT FROM THE CHILDREN ONCOLOGY GROUP
Q94067789MBCL-21. EARLY CHILDHOOD MEDULLOBLASTOMA: SUBGROUP-SPECIFIC SURVIVAL IN PATIENTS TREATED WITH SYSTEMIC CHEMOTHERAPY AND INTRAVENTRICULAR MTX TO AVOID CRANIOSPINAL RADIOTHERAPY
Q64972831MBCL-41. TREATMENT FAILURE PATTERNS ACROSS MEDULLOBLASTOMA SUBGROUPS WITHIN A PROSPECTIVE PHASE II CLINICAL TRIAL OF RISK-ADAPTED, VOLUME-REDUCED RADIATION THERAPY AND DOSE-INTENSE CHEMOTHERAPY WITH STEM CELL SUPPORT.
Q94065878MBCL-42. SECOND GENERATION MOLECULAR SUBGROUPING OF MEDULLOBLASTOMA: TOWARDS A WORKING CONSENSUS OF GROUP 3/4 SUBTYPES
Q94065636MBCL-44. THE MOLECULAR AND CLINICAL LANDSCAPE OF INFANT MEDULLOBLASTOMA (iMB): RESULTS AND MOLECULAR ANALYSIS FROM A PROSPECTIVE, MULTICENTER PHASE II TRIAL (SJYC07)
Q94067735MBRS-07. BCOR LOSS IMPACTS SHH MEDULLOBLASTOMA FORMATION VIA TRANSCRIPTIONAL UP-REGULATION OF
Q64983697MBRS-19. BIOCHEMICAL AND ONCOGENIC CHARACTERIZATION OF HOTSPOT KBTBD4 MUTATIONS IN MEDULLOBLASTOMA.
Q94068107MBRS-28. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF MEDULLOBLASTOMA
Q64926246MBRS-34. MOLECULAR CHARACTERIZATION OF RECURRENT MEDULLOBLASTOMA REVEALS AN UNEXPECTEDLY HIGH INCIDENCE OF SECONDARY MALIGNANCY.
Q94331854MEDU-21. LOSS OF THE TRANSCRIPTIONAL CO-REPRESSOR BCOR LEADS TO OVEREXPRESSION OF THE GROWTH FACTOR IGF2 AND SHH MEDULLOBLASTOMA TUMOR FORMATION
Q54855151MEDU-24. INSTRUMENTAL ROLE OF THE PHOTORECEPTOR PROGRAM IN GROUP 3 MEDULLOBLASTOMA THROUGH THE TRANSCRIPTION FACTOR NRL.
Q58177980MEDULLOBLASTOMA
Q56880484MEDULLOBLASTOMA
Q64947029MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes.
Q46032472MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS.
Q91596369Medulloblastoma
Q42739353Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group.
Q36920479Medulloblastoma comprises four distinct molecular variants
Q30040534Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
Q91679780Medulloblastoma genomics in the modern molecular era
Q35099027Medulloblastoma subgroups remain stable across primary and metastatic compartments
Q37317515Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress
Q91826570Medulloblastomics revisited: biological and clinical insights from thousands of patients
Q37469904Medulloblastomics: the end of the beginning
Q53201641MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma.
Q27350129MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma
Q45826769Molecular genetic analysis of the hepatocyte growth factor/MET signaling pathway in pediatric medulloblastoma
Q35101347Molecular subgroups of medulloblastoma
Q34167499Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
Q24615271Molecular subgroups of medulloblastoma: the current consensus
Q37896219Mouse models of medulloblastoma
Q39334547Multiple CDK/CYCLIND genes are amplified in medulloblastoma and supratentorial primitive neuroectodermal brain tumor
Q28237604Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
Q33584640MyoD is a tumor suppressor gene in medulloblastoma
Q57954536NEURO/MEDICAL ONCOLOGY
Q52658142NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma.
Q34515911New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs
Q34576839Nexilin, a cardiomyopathy-associated F-actin binding protein, binds and regulates IRS1 signaling in skeletal muscle cells
Q38525123Next-generation (epi)genetic drivers of childhood brain tumours and the outlook for targeted therapies
Q37630205Normal and oncogenic roles for microRNAs in the developing brain
Q39205931Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation
Q41701616Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells
Q56898447OMICS AND PROGNSTIC MARKERS
Q42423388OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas
Q36641703Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation
Q104753822Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)
Q39539408PCDH10 is a candidate tumour suppressor gene in medulloblastoma.
Q46357280PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.
Q56999046PEDIATRICS LABORATORY RESEARCH
Q45957447PM-09ESTABLISHMENT AND MOLECULAR CHARACTERIZATION OF PATIENT-DERIVED XENOGRAFT MODELS OF PEDIATRIC BRAIN TUMORS.
Q94354022PM-09REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1B
Q57954516PROGNOSTIC SIGNIFICANCE OF CLINICAL, HISTOPATHOLOGICAL, AND MOLECULAR CHARACTERISTICS OF MEDULLOBLASTOMAS IN THE PROSPECTIVE HIT2000 MULTICENTER CLINICAL TRIAL COHORT
Q45834943PTPS-11ATYPICAL TERATOID/RHABDOID TUMOUR IS AN EPIGENETICALLY HETEROGENEOUS DISEASE CHARACTERIZED BY SUBGROUP SPECIFIC SUPER-ENHANCERS.
Q34545220Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.
Q112645015Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma
Q96232268Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource
Q98191465Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma
Q35960250Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
Q34982536Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children
Q91488034Phase II Study of Nonmetastatic Desmoplastic Medulloblastoma in Children Younger Than 4 Years of Age: A Report of the Children's Oncology Group (ACNS1221)
Q40461175Pleiotropic role for MYCN in medulloblastoma.
Q33764662Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort
Q37004219Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis
Q55479624Proteomic analysis of Medulloblastoma reveals functional biology with translational potential.
Q35630706Proteomic profiling of high risk medulloblastoma reveals functional biology
Q57158811Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups
Q35635358Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma
Q35837393Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples
Q37312706Real-time PCR assay based on the differential expression of microRNAs and protein-coding genes for molecular classification of formalin-fixed paraffin embedded medulloblastomas
Q37636027Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis
Q34354839Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
Q24339074Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
Q92154185Resolving medulloblastoma cellular architecture by single-cell genomics
Q36901551Risk stratification of childhood medulloblastoma in the molecular era: the current consensus
Q91699914Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials
Q88737429Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial
Q43153279Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays
Q30156001Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma
Q46225692STRUCTURAL VARIANTS SHUFFLE CHROMATIN TO ACTIVATE GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA.
Q92484009SWI/SNF complex heterogeneity relates with polyphenotypic differentiation, prognosis and immune response in rhabdoid tumors
Q91933328Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes
Q29547191Signatures of mutational processes in human cancer
Q38340521Silencing of thrombospondin-1 is critical for myc-induced metastatic phenotypes in medulloblastoma
Q35742331Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling
Q39521830Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells.
Q41969132Spatial heterogeneity in medulloblastoma
Q54969362Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
Q28260516Subgroup-specific alternative splicing in medulloblastoma
Q36929844Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma
Q28271811Subgroup-specific structural variation across 1,000 medulloblastoma genomes
Q46359308TB-17A COMPREHENSIVE PAN-CANCER ANALYSIS OF CHILDHOOD MALIGNANCIES.
Q37316068TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
Q45836126TMOD-01BCOR IS A NOVEL TUMOR SUPPRESSOR GENE IN SHH-DRIVEN MEDULLOBLASTOMA.
Q42689215Targeting sonic hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-like kinases.
Q36032753Targeting the enhancer of zeste homologue 2 in medulloblastoma.
Q92352124TelomereHunter - in silico estimation of telomere content and composition from cancer genomes
Q38321654The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis
Q24301908The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma
Q48508947The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors
Q36490004The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants
Q38008153The clinical implications of medulloblastoma subgroups
Q28291406The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
Q37987505The epigenetics of brain tumors.
Q37439475The evolution and application of techniques in molecular biology to human brain tumors: a 25 year perspective.
Q28301196The genetic landscape of the childhood cancer medulloblastoma
Q37738138The genetics of pediatric brain tumors
Q50421569The landscape of genomic alterations across childhood cancers.
Q24629817The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors
Q38083796The role of chromatin remodeling in medulloblastoma.
Q46567834The whole-genome landscape of medulloblastoma subtypes
Q47906350Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
Q38123270Transitioning from genotypes to epigenotypes: why the time has come for medulloblastoma epigenomics
Q39174290Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters
Q42558518Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization
Q64939961Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma.
Q56968690UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs
Q24294672Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics
Q34979270WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma
Q98283974WNT-activated embryonal tumors of the pineal region: ectopic medulloblastomas or a novel pineoblastoma subgroup?
Q28507494YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
Q92163648scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy