Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages

scientific article

Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1997PNAS...94.6954X
P356DOI10.1073/PNAS.94.13.6954
P932PMC publication ID21266
P698PubMed publication ID9192673
P5875ResearchGate publication ID14025929

P2093author name stringY Xia
J L Zweier
P2860cites workApparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxideQ29547245
Nitric oxide synthases: Roles, tolls, and controlsQ29618629
Measurement of endothelial cell free radical generation: evidence for a central mechanism of free radical injury in postischemic tissuesQ33579059
Microenvironmental arginine depletion by macrophages in vivoQ36043250
Regulation of macrophage functions by L-arginineQ36356213
Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cellsQ36356339
Nitric oxide synthases reveal a role for calmodulin in controlling electron transferQ36672374
Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injuryQ37542333
Cloning and characterization of inducible nitric oxide synthase from mouse macrophagesQ38329463
Production of hydroxyl radical by decomposition of superoxide spin-trapped adductsQ38583948
Assembly and regulation of NADPH oxidase and nitric oxide synthaseQ40388524
Regulation of biosynthesis of nitric oxide.Q40389134
Nitric oxide: a physiologic messenger moleculeQ40394921
Nitric oxide synthases: properties and catalytic mechanismQ40401516
Free radicals and phagocytic cells.Q40401665
Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidaseQ40512506
Trace levels of bacterial lipopolysaccharide prevent interferon-gamma or tumor necrosis factor-alpha from enhancing mouse peritoneal macrophage respiratory burst capacityQ41372837
Generation of superoxide by purified brain nitric oxide synthaseQ41590269
Peroxynitrite-induced luminol chemiluminescenceQ42267094
Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistryQ42285845
Arginine metabolism in woundsQ43968290
Nitrosative stress: activation of the transcription factor OxyR.Q54580956
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.Q55057549
Activated macrophages kill tumour cells by releasing arginaseQ59065414
Bactericidal activity of peroxynitriteQ67568060
Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediateQ68060992
Suppression of macrophage antimicrobial activity by a tumor cell productQ70437909
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)6954-6958
P577publication date1997-06-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleSuperoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages
P478volume94

Reverse relations

cites work (P2860)
Q35014145A mitochondrial superoxide theory for oxidative stress diseases and aging
Q35763336A neurovascular perspective for long-term changes after brain trauma
Q34987424A potential role of macrophage activation in the treatment of cancer
Q36923029AMP-activated protein kinase regulates L-arginine mediated cellular responses
Q92601237AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells
Q34409752ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005.
Q43669436Activation of poly(ADP-ribose) polymerase in severe hemorrhagic shock and resuscitation
Q42476344Activation of src tyrosine kinases by peroxynitrite
Q46771398Acute restraint stress induces endothelial dysfunction: role of vasoconstrictor prostanoids and oxidative stress
Q40896628Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide
Q96607262An innovative cell model revealed the inhibitory effect of flavanone structure on peroxynitrite production through interaction with the IKKβ kinase domain at ATP binding site
Q40312662Anti-tumour necrosis factor-alpha therapy over conventional therapy improves endothelial function in adults with rheumatoid arthritis.
Q37278531Arginase activity mediates retinal inflammation in endotoxin-induced uveitis.
Q35216439Arginase and asthma: novel insights into nitric oxide homeostasis and airway hyperresponsiveness
Q28385094Arginase and pulmonary diseases
Q36977086Arginase and vascular aging
Q34800913Arginase in retinopathy
Q46516143Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation
Q24650052Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives
Q34314553Arginine deprivation and autophagic cell death in cancer
Q34199042Arginine metabolism and the synthesis of nitric oxide in the nervous system
Q87506486Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells
Q52372449Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach.
Q48101394Astrocytes rather than neurones mediate interleukin-1beta dependent nitric oxide and superoxide radical release in primary hypothalamic rat cell cultures
Q40198573Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells
Q30558251Atheroprotective effects of neuronal nitric oxide synthase in apolipoprotein e knockout mice
Q33649712Atherosclerosis: A Link Between Lipid Intake and Protein Tyrosine Nitration
Q38770238Berberine Decreased Inducible Nitric Oxide Synthase mRNA Stability through Negative Regulation of Human Antigen R in Lipopolysaccharide-Induced Macrophages
Q33593640Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension
Q36403503Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.
Q87193200Carbamazepine-mediated pro-oxidant effects on the unicellular marine algal species Dunaliella tertiolecta and the hemocytes of mussel Mytilus galloprovincialis
Q34789751Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
Q47099413Cardioprotective Effect of Resveratrol in a Postinfarction Heart Failure Model
Q37412845Cardiovascular consequences when nitric oxide and lipid signaling converge
Q36244638Changes in atherosclerotic plaques induced by inhalation of diesel exhaust
Q35237477Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.
Q35567372Chronic exercise preserves renal structure and hemodynamics in spontaneously hypertensive rats
Q34330689Comparative analysis of mycobacterial truncated hemoglobin promoters and the groEL2 promoter in free-living and intracellular mycobacteria
Q41683268Comparative proteomic analysis of growth hormone secretagogue A233 treatment of murine macrophage cells J774A.2 indicates it has a role in antiviral innate response
Q41897633Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence
Q36682074Competitive metabolism of L-arginine: arginase as a therapeutic target in asthma
Q37346659Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity.
Q41824174Contribution of nitric oxide produced by inducible nitric oxide synthase to vascular responses of mesenteric arterioles in streptozotocin-diabetic rats
Q85526746Contribution of oxidative stress and prostanoids in endothelial dysfunction induced by chronic fluoxetine treatment
Q80510725Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetes
Q35066832Cytokines Modulate the "Immune-Metabolism" Interactions during Behçet Disease: Effect on Arginine Metabolism
Q36962909Cytokines and lipopolysaccharides induce inducible nitric oxide synthase but not enzyme activity in adult rat cardiomyocytes
Q54446139DNA polymerase V allows bypass of toxic guanine oxidation products in vivo.
Q33712644Deficiency of lung antioxidants in idiopathic pulmonary arterial hypertension
Q37085195Deletion of inducible nitric oxide synthase provides cardioprotection in mice with 2-kidney, 1-clip hypertension
Q40770011Determination of the enhancing action of HSP90 on neuronal nitric oxide synthase by EPR spectroscopy
Q44010259Differential modulation of host macrophage function by AK-5 tumor is dependent on the site of tumor transplantation
Q47681636Differential sensitivity of the tyrosyl radical of mouse ribonucleotide reductase to nitric oxide and peroxynitrite
Q33815495Dose dependent effects of reactive oxygen and nitrogen species on the function of neuronal nitric oxide synthase
Q61816639Dystrophin Deficiency Leads to Genomic Instability in Human Pluripotent Stem Cells via NO Synthase-Induced Oxidative Stress
Q41895180Effect of Cimetidine on Nitro-Oxidative Stress in a Rat Model of Periodontitis
Q42912295Effect of Endurance Exercise Training on Oxidative Stress in Spontaneously Hypertensive Rats (SHR) After Emergence of Hypertension
Q37245523Effect of asymmetric dimethylarginine (ADMA) on heart failure development
Q44593872Effect of nitric oxide and nitroxide SOD-mimic on the recovery of isolated rat heart following ischemia and reperfusion
Q44355165Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep
Q43791434Effect of some hexahydroimidazo[1,2-c]pyrimidines in inflammatory responses involving leucocytes and macrophages
Q41974155Effects of xanthine oxidase inhibition with febuxostat on the development of nephropathy in experimental type 2 diabetes
Q40485897Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin
Q33863119Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase
Q53587623Endothelial nitric oxide synthase (NOS3) knockout decreases NOS2 induction, limiting hyperoxygenation and conferring protection in the postischemic heart.
Q73176780Endothelium-dependent relaxation of rabbit atherosclerotic aorta was not restored by control of hyperlipidemia: the possible role of peroxynitrite (ONOO(-))
Q43603046Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases
Q88034813Environmental Agents, Oxidative Stress and Autoimmunity
Q38888494Evaluation of the presence of reduced nicotinamide adenine dinucleotide phosphate in bacterial metabolites used as immunostimulators and its role in nitric oxide induction
Q44026944Evidence that NOS2 acts as a trigger and mediator of late preconditioning induced by acute systemic hypoxia.
Q52324333Examination of the Role of Mitochondrial Morphology and Function in the Cardioprotective Effect of Sodium Nitrite Administered 24 h Before Ischemia/Reperfusion Injury.
Q35927810Exposure to diesel exhaust up-regulates iNOS expression in ApoE knockout mice
Q36304952Expression of Cationic Amino Acid Transporter 2 Is Required for Myeloid-Derived Suppressor Cell-Mediated Control of T Cell Immunity
Q37332166Fast ferrous heme-NO oxidation in nitric oxide synthases
Q57316304Fish nutrients decrease expression levels of tumor necrosis factor-α in cultured human macrophages
Q33831873Free radical-operated proteotoxic stress in macrophages primed with lipopolysaccharide.
Q35544101From molecules to mammals: what's NOS got to do with it?
Q36994325Genetic elimination of eNOS reduces secondary complications of experimental subarachnoid hemorrhage
Q35022594Glial cell response: A pathogenic factor in Parkinson's disease.
Q38928508Growth Factors in the Pathogenesis of Retinal Neurodegeneration in Diabetes Mellitus
Q42505831HMG-CoA reductase inhibitor stabilizes rabbit atheroma by increasing basal NO and decreasing superoxide
Q24307745Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase
Q57811107Hesperidin Prevents Nitric Oxide Deficiency-Induced Cardiovascular Remodeling in Rats via Suppressing TGF-β1 and MMPs Protein Expression
Q33739113Hypoxia and reoxygenation induce endothelial nitric oxide synthase uncoupling in endothelial cells through tetrahydrobiopterin depletion and S-glutathionylation
Q33902060Hypoxic pulmonary blood flow redistribution and arterial oxygenation in endotoxin-challenged NOS2-deficient mice
Q41928225Imaging of compartmentalised intracellular nitric oxide, induced during bacterial phagocytosis, using a metalloprotein-gold nanoparticle conjugate.
Q39283587Immunomodulatory effects of Bacillus subtilis (natto) B4 spores on murine macrophages
Q28346380Impaired response to interferon-gamma in activated macrophages due to tyrosine nitration of STAT1 by endogenous nitric oxide
Q34492874Importance of nitric oxide synthase in the control of infection by Bacillus anthracis.
Q37324796Increased nitration and carbonylation of proteins in MRL+/+ mice exposed to trichloroethene: potential role of protein oxidation in autoimmunity
Q40720920Inducible nitric oxide synthase (NOS2) expressed in septic patients is nitrated on selected tyrosine residues: implications for enzymic activity.
Q40921777Inducible nitric oxide synthase inhibitor of the Chinese herb I. Saposhnikovia divaricata (Turcz.) Schischk
Q40835606Inducible nitric oxide synthase inhibitors of Chinese herbs. Part 2: naturally occurring furanocoumarins
Q33954239Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells.
Q56567926Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
Q42082401Inducible nitric oxide synthase-derived superoxide contributes to hypereactivity in small mesenteric arteries from a rat model of chronic heart failure
Q35170207Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
Q31887923Inhibition by costunolide of phorbol ester-induced transcriptional activation of inducible nitric oxide synthase gene in a human monocyte cell line THP-1.
Q40870744Inhibition by parthenolide of phorbol ester-induced transcriptional activation of inducible nitric oxide synthase gene in a human monocyte cell line THP-1.
Q77919975Inhibition of GTP binding to Rac2 by peroxynitrite: potential role for tyrosine modification
Q34532029Inhibition of actin polymerization by peroxynitrite modulates neutrophil functional responses
Q28373349Inhibition of inducible nitric oxide synthase improves graft function and reduces tubulointerstitial injury in renal allograft rejection
Q37807194Insulin says NO to cardiovascular disease
Q34724693Intestinal NADPH oxidase 2 activity increases in a neonatal rat model of necrotizing enterocolitis.
Q38635972Intraspinal TLR4 activation promotes iron storage but does not protect neurons or oligodendrocytes from progressive iron-mediated damage.
Q95854685Intravenous Arginine Administration Downregulates NLRP3 Inflammasome Activity and Attenuates Acute Kidney Injury in Mice with Polymicrobial Sepsis
Q77507782Involvement of superoxide and nitric oxide on airway inflammation and hyperresponsiveness induced by diesel exhaust particles in mice
Q44746404Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells
Q40815078Involvement of the perferryl complex of nitric oxide synthase in the catalysis of secondary free radical formation
Q92163260Iron Supplementation Therapy, A Friend and Foe of Mycobacterial Infections?
Q44733549L-Arginine supplementation improves antioxidant defenses through L-arginine/nitric oxide pathways in exercised rats
Q35155944L-arginine metabolism in myeloid cells controls T-lymphocyte functions.
Q42124934Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice.
Q36148204Lack of inducible NO synthase reduces oxidative stress and enhances cardiac response to isoproterenol in mice with deoxycorticosterone acetate-salt hypertension
Q40958378Lipid hydroperoxides inhibit nitric oxide production in RAW264.7 macrophages
Q46280862Lung Ischaemia-Reperfusion Injury: The Role of Reactive Oxygen Species
Q27300703Macrophage Bactericidal Activities against Staphylococcus aureus Are Enhanced In Vivo by Selenium Supplementation in a Dose-Dependent Manner
Q40421152Macrophage-derived nitric oxide initiates T-cell diapedesis and tumor rejection
Q33631306Mammalian nitric oxide synthases
Q34111316Markers of oxidative and nitrosative stress in systemic lupus erythematosus: correlation with disease activity
Q36577103Mechanisms of disease: Pre-eclampsia
Q36203539Methods of quantitative analysis of the nitric oxide metabolites nitrite and nitrate in human biological fluids
Q28660732Mitochondrial redox signaling: Interaction of mitochondrial reactive oxygen species with other sources of oxidative stress
Q41814727Modulation of NO and ROS production by AdiNOS transduced vascular cells through supplementation with L-Arg and BH4: implications for gene therapy of restenosis
Q36461910Modulation of myocardial contraction by peroxynitrite
Q34100098Modulation of polymorphonuclear leukocytes function by nitric oxide
Q40409036Molecular mechanisms underlying the role of nitric oxide in the cardiovascular system
Q40311287Monitoring in real time with a microelectrode the release of reactive oxygen and nitrogen species by a single macrophage stimulated by its membrane mechanical depolarization
Q28571780Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes
Q38160782Myeloid derived suppressor cells in physiological and pathological conditions: the good, the bad, and the ugly
Q36002621Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4.
Q46522534NADPH Oxidase Plays a Role on Ethanol-Induced Hypertension and Reactive Oxygen Species Generation in the Vasculature.
Q38596162NADPH oxidases-do they play a role in TRPC regulation under hypoxia?
Q38020147NOS-2 signaling and cancer therapy
Q82029459Neuroinflammation and Parkinson's disease
Q28363357Neuronal nitric oxide synthase generates superoxide from the oxygenase domain
Q54344856New role for L-arginine in regulation of inducible nitric-oxide-synthase-derived superoxide anion production in raw 264.7 macrophages.
Q28513008Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264
Q35939206Nitrative stress in cerebral endothelium is mediated by mGluR5 in hyperhomocysteinemia
Q73862353Nitric oxide (NO.) stabilizes whereas nitrosonium (NO+) enhances filopodial outgrowth by rat retinal ganglion cells in vitro
Q43613111Nitric oxide and Coxsackievirus B3 myocarditis: differential expression of inducible nitric oxide synthase in mouse heart after infection with virulent or attenuated virus
Q34019768Nitric oxide and intestinal inflammation
Q24645400Nitric oxide and peroxynitrite in health and disease
Q35001939Nitric oxide and redox mechanisms in the immune response
Q36832237Nitric oxide and related enzymes in asthma: relation to severity, enzyme function and inflammation
Q53600984Nitric oxide and superoxide in rat mesangial cells: modulation by C-reactive protein.
Q77802828Nitric oxide in the failing myocardium
Q47778701Nitric oxide paradox in asthma
Q74233359Nitric oxide protects nitric oxide synthase function from hydroxyl radical-induced inhibition
Q75196844Nitric oxide release by hemocytes of the mussel Mytilus galloprovincialis Lmk was provoked by interleukin-2 but not by lipopolysaccharide
Q35765975Nitric oxide signaling and the regulation of myocardial function.
Q49501122Nitric oxide signalling in cardiovascular health and disease.
Q74038500Nitric oxide synthase activity in mitochondria
Q42535395Nitric oxide synthases and atrial fibrillation
Q44242253Nitric oxide synthases and peripheral cardiovascular system
Q73011328Nitric oxide synthases catalyze superoxide formation
Q33932627Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination
Q31162430Nitrosative stress and nitrated proteins in trichloroethene-mediated autoimmunity
Q43557689Nitroxyl oxidizes NADPH in a superoxide dismutase inhibitable manner
Q35173250Nonimmune Cells Contribute to Crosstalk between Immune Cells and Inflammatory Mediators in the Innate Response to Trypanosoma cruzi Infection
Q44018844Noninvasive diagnostic tool for inflammation-induced oxidative stress using electron spin resonance spectroscopy and an extracellular cyclic hydroxylamine
Q43167318Novel antioxidant technology for prostate cancer chemoprevention and treatment
Q35086748Obligatory role of heat shock protein 90 in iNOS induction
Q38434331Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage
Q52928868Optically-controlled bacterial metabolite for cancer therapy.
Q39737681Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
Q43794690Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities
Q30487724Oxidative stress and compartment of gene expression determine proatherosclerotic effects of inducible nitric oxide synthase.
Q36480016Oxidative stress and the development of endothelial dysfunction in congenital heart disease with increased pulmonary blood flow: lessons from the neonatal lamb
Q33333142Oxidative stress in children late after Kawasaki disease: relationship with carotid atherosclerosis and stiffness
Q26829529Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus
Q34201782Oxygen reduction by nitric-oxide synthases
Q40857326Oxygen tension limits nitric oxide synthesis by activated macrophages
Q38047052PGE(2)-driven induction and maintenance of cancer-associated myeloid-derived suppressor cells
Q40715078PPAR gamma ligands inhibit nitrotyrosine formation and inflammatory mediator expressions in adjuvant-induced rheumatoid arthritis mice
Q35123478Paradoxes of nitric oxide in the diabetic kidney
Q33610044Pathophysiology of nitric oxide and related species: free radical reactions and modification of biomolecules
Q35043095Peroxynitrite (ONOO-) is endogenously produced in arabidopsis peroxisomes and is overproduced under cadmium stress.
Q44626562Peroxynitrite Decreases Dopamine???s Vasoconstrictive Activity
Q33836818Peroxynitrite and inflammatory bowel disease
Q38211432Peroxynitrite and peroxiredoxin in the pathogenesis of experimental amebic liver abscess.
Q33775518Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibition
Q44263972Peroxynitrite-induced inhibition and nitration of cardiac myofibrillar creatine kinase
Q74831208Peroxynitrite: a biologically significant oxidant
Q42119587Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme
Q59093280Plants just say NO to pathogens
Q33542692Postischemic reperfusion injury and allograft dysfunction: is allograft rejection the result of a fateful confusion by the immune system of danger and benefit?
Q38239610Posttranslational protein modifications by reactive nitrogen and chlorine species and strategies for their prevention and elimination
Q39076238Prokaryotic expression and functional analysis of the Mb1514 gene in Mycobacterium bovis
Q35132036Propofol increases morbidity and mortality in a rat model of sepsis
Q96432088Prostate carcinogenesis: inflammatory storms
Q35949671Protective role of Bacillus anthracis exosporium in macrophage-mediated killing by nitric oxide.
Q46466667Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells
Q40271384ROS production and angiogenic regulation by macrophages in response to heat therapy
Q24630289Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
Q33815525Reactive oxygen and nitrogen species regulate inducible nitric oxide synthase function shifting the balance of nitric oxide and superoxide production
Q38192852Reactive oxygen species in diabetic nephropathy: friend or foe?
Q36392238Reactive oxygen species: toxic molecules or spark of life?
Q77419161Reciprocal effects of interleukin-4 and interferon-gamma on immunoglobulin E-mediated mast cell degranulation: a role for nitric oxide but not peroxynitrite or cyclic guanosine monophosphate
Q37009925Regulation of DDAH1 as a Potential Therapeutic Target for Treating Cardiovascular Diseases
Q29614284Regulation of immune responses by L-arginine metabolism
Q33706925Regulation of the iron regulatory proteins by reactive nitrogen and oxygen species.
Q34665101Regulatory haplotypes in ARG1 are associated with altered bronchodilator response
Q35165294Relationship of electrophilic stress to aging
Q36681658Reprint of "oxidative alterations of cyclooxygenase during atherogenesis" [Prostag. Oth. Lipid. M. 80 (2006) 1-14].
Q35009522Review article: oxidative stress as a pathogenic factor in inflammatory bowel disease--radicals or ridiculous?
Q33548209Review article: the potential role of nitric oxide in chronic inflammatory bowel disorders
Q50121100Role of nitric oxide in lipopolysaccharide-induced oxidant stress in the rat kidney.
Q38047690Role of poly(ADP-ribose) polymerases in the regulation of inflammatory processes
Q77089411Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion
Q42718346S-glutathionylation reshapes our understanding of endothelial nitric oxide synthase uncoupling and nitric oxide/reactive oxygen species-mediated signaling
Q92823213Salmonella and Reactive Oxygen Species: A Love-Hate Relationship
Q27015676Salmonella and cancer: from pathogens to therapeutics
Q74582897Scavenging of peroxynitrite by a phenolic/peroxidase system prevents oxidative damage to DNA
Q41047576Screening of edible Japanese plants for nitric oxide generation inhibitory activities in RAW 264.7 cells
Q40757279Screening of edible Japanese plants for suppressive effects on phorbol ester-induced superoxide generation in differentiated HL-60 cells and AS52 cells
Q64956089Sensory nerves mediate spontaneous behaviors in addition to inflammation in a murine model of psoriasis.
Q58075704Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation
Q42017864The NADPH oxidase Nox4 and aging in the heart.
Q36544017The biology of nitric oxide and other reactive intermediates in systemic lupus erythematosus
Q35101936The decomposition of peroxynitrite to nitroxyl anion (NO-) and singlet oxygen in aqueous solution
Q51301590The inducible nitric oxide synthase inhibitor BBS-2 prevents acute lung injury in sheep after burn and smoke inhalation injury.
Q35072055The nitric oxide pathway in the cardiovascular system.
Q33961915The role of NOS in heart failure: lessons from murine genetic models
Q37961913The role of Toll-like receptors and adaptive immunity in the development of protective or pathological immune response triggered by the Trypanosoma cruzi protozoan.
Q34509144The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes
Q38223301The role of arginine and the modified arginine deiminase enzyme ADI-PEG 20 in cancer therapy with special emphasis on Phase I/II clinical trials
Q34006323The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide
Q36268354The therapeutic potential of drugs targeting the arginase pathway in asthma
Q40967012Theaflavin-3,3'-digallate from black tea blocks the nitric oxide synthase by down-regulating the activation of NF-kappaB in macrophages
Q46367827Thiomaleimide Functionalization for Selective Biological Fluorescence Detection of Peroxynitrite as Tested in HeLa and RAW 264.7 Cells
Q46452154Threshold levels of extracellular l-arginine that trigger NOS-mediated ROS/RNS production in cardiac ventricular myocytes
Q46428405Trace analysis of oxidized, nitrated, and chlorinated aromatic amino acids by capillary electrophoresis with electroosmotic flow modification allowing large-volume sample stacking
Q36948658Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase
Q38218886Transplantation and inflammation: implications for the modification of chemokine function
Q44168316Tyrosine nitration in prostaglandin H(2) synthase
Q34430029Tyrosine nitration: localisation, quantification, consequences for protein function and signal transduction
Q31969110Unraveling peroxynitrite formation in biological systems.
Q33639014Vascular neural network phenotypic transformation after traumatic injury: potential role in long-term sequelae
Q73978566Vascular oxidant stress early after balloon injury: evidence for increased NAD(P)H oxidoreductase activity
Q35814867Whispers and shouts in the pathogenesis of acute renal ischaemia
Q36914428gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury
Q36386284iNOS null MRL+/+ mice show attenuation of trichloroethene-mediated autoimmunity: contribution of reactive nitrogen species and lipid-derived reactive aldehydes
Q39012371l-DOPA-induced dyskinesia and neuroinflammation: do microglia and astrocytes play a role?

Search more.