| P50 | author | Michael Wakelam | Q15994807 |
| P2093 | author name string | Simon A Rudge | |
| P2860 | cites work | Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas. | Q52180037 |
| | Cinderella finds her shoe: the first Vps34 inhibitor uncovers a new PI3K-AGC protein kinase connection. | Q54309767 |
| | INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival. | Q54317525 |
| | High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity | Q57986498 |
| | High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 |
| | Gene structure, expression profiling and mutation analysis of the tumour suppressor SHIP1 in Caucasian acute myeloid leukaemia | Q59511645 |
| | Purification and biochemical characterization of a mammalian phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase | Q70825891 |
| | Identification and characterization of the phosphatidylinositol-(4, 5)-bisphosphate 5-phosphatase in human platelets | Q72237867 |
| | Purification and characterization of a 43-kDa membrane-associated inositol polyphosphate 5-phosphatase from human placenta | Q72954285 |
| | Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies | Q73722520 |
| | Expression of the PTEN tumour suppressor protein during human development | Q73911026 |
| | Gene signatures of progression and metastasis in renal cell cancer | Q81098660 |
| | High expression of obesity-linked phosphatase SHIP2 in invasive breast cancer correlates with reduced disease-free survival | Q82877917 |
| | SnapShot: Lipid kinase and phosphatase reaction pathways | Q87121153 |
| | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
| | A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y | Q22010933 |
| | Identification and characterization of a novel inositol polyphosphate 5-phosphatase | Q22253849 |
| | The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase | Q22253894 |
| | Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate | Q22254632 |
| | Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity | Q24291835 |
| | Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease | Q24291963 |
| | Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ... | Q24292896 |
| | SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation | Q24293490 |
| | Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 |
| | Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function | Q24295164 |
| | The Human Phosphatidylinositol Phosphatase SAC1 Interacts with the Coatomer I Complex | Q24296999 |
| | Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases | Q24298042 |
| | The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases | Q24299329 |
| | A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy | Q24305126 |
| | Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex | Q24307982 |
| | Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase | Q24309311 |
| | TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta | Q24310394 |
| | Characterization of a cDNA encoding the 43-kDa membrane-associated inositol-polyphosphate 5-phosphatase | Q24311855 |
| | The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family | Q24311889 |
| | Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9 | Q24313006 |
| | Properties of type II inositol polyphosphate 5-phosphatase | Q24314934 |
| | Cloning and expression of a human placenta inositol 1,3,4,5-tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase | Q24317530 |
| | The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 |
| | The Isolation and Characterization of cDNA Encoding Human and Rat Brain Inositol Polyphosphate 4-Phosphatase | Q24318660 |
| | Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 |
| | P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 |
| | Association of SET domain and myotubularin-related proteins modulates growth control | Q24323057 |
| | INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse | Q24323384 |
| | mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) | Q24324148 |
| | Increased insulin action in SKIP heterozygous knockout mice | Q24324738 |
| | A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast | Q24336385 |
| | 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase | Q24336639 |
| | The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase | Q24336782 |
| | Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. | Q24515262 |
| | The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane | Q24523405 |
| | Dent Disease with mutations in OCRL1 | Q24530643 |
| | Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1 | Q24531380 |
| | Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2 | Q24531452 |
| | The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase | Q24567715 |
| | Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies | Q24651557 |
| | Pheromone-regulated genes required for yeast mating differentiation | Q24678064 |
| | The cellular and physiological functions of the Lowe syndrome protein OCRL1 | Q26862286 |
| | Autophagy-mediated tumor promotion | Q27011920 |
| | Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness | Q28590549 |
| | Characterization of the murine Inpp4b gene and identification of a novel isoform | Q28590569 |
| | Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate | Q28611035 |
| | Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation | Q28616026 |
| | Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 |
| | Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B | Q28646131 |
| | Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B | Q28646376 |
| | The TPTE gene family: cellular expression, subcellular localization and alternative splicing | Q28678657 |
| | The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101 | Q28678835 |
| | A molecular signature of metastasis in primary solid tumors | Q29614442 |
| | Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 |
| | The nuts and bolts of AGC protein kinases | Q29617465 |
| | The emerging mechanisms of isoform-specific PI3K signalling | Q29617954 |
| | The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase | Q29618387 |
| | Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction | Q29618388 |
| | Cellular uptake of the tat protein from human immunodeficiency virus | Q29620627 |
| | Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axis | Q30536784 |
| | Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2. | Q30952448 |
| | Regulation of IGF-1/PI3K/Akt signalling by the phosphoinositide phosphatase pharbin | Q33112069 |
| | Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness | Q33399066 |
| | Regulation of p110delta PI 3-kinase gene expression | Q33428537 |
| | PTEN 2, a Golgi-associated testis-specific homologue of the PTEN tumor suppressor lipid phosphatase | Q33940647 |
| | 5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells | Q33965618 |
| | SHIP1 inhibition increases immunoregulatory capacity and triggers apoptosis of hematopoietic cancer cells. | Q34008167 |
| | The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics | Q34069966 |
| | Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex | Q34101673 |
| | Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1. | Q34131489 |
| | Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers | Q34153121 |
| | Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer. | Q34158474 |
| | Loss of Inositol Polyphosphate 5-Phosphatase Is an Early Event in Development of Cutaneous Squamous Cell Carcinoma | Q34203794 |
| | Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling | Q34212404 |
| | Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cells | Q34281754 |
| | An alternative to SH2 domains for binding tyrosine-phosphorylated proteins | Q34292972 |
| | Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death | Q34323114 |
| | The minimal essential core of a cysteine-based protein-tyrosine phosphatase revealed by a novel 16-kDa VH1-like phosphatase, VHZ. | Q34327426 |
| | The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1. | Q34328370 |
| | Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 |
| | TPIP: a novel phosphoinositide 3-phosphatase | Q28364566 |
| | Pten is essential for embryonic development and tumour suppression | Q28509238 |
| | Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate | Q28511509 |
| | Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J | Q28511673 |
| | Essential role of phosphoinositide metabolism in synaptic vesicle recycling | Q28511682 |
| | Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network | Q28512973 |
| | Developmentally regulated alternative splicing in a novel synaptojanin | Q28513174 |
| | Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 |
| | A presynaptic inositol-5-phosphatase | Q28565411 |
| | Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity | Q28567201 |
| | Synaptojanin 2, a novel synaptojanin isoform with a distinct targeting domain and expression pattern | Q28576018 |
| | Pharbin, a novel inositol polyphosphate 5-phosphatase, induces dendritic appearances in fibroblasts | Q28578087 |
| | rSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cells | Q28580019 |
| | Novel inositol polyphosphate 5-phosphatase localizes at membrane ruffles | Q28581567 |
| | The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation. | Q28583817 |
| | A PTEN-like phosphatase with a novel substrate specificity | Q28585516 |
| | Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis | Q28585950 |
| | Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems | Q28586004 |
| | Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2 | Q28590542 |
| | Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase | Q27631711 |
| | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer | Q27646556 |
| | Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis | Q27670687 |
| | PI3K signalling in inflammation | Q27690632 |
| | Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B | Q27860731 |
| | PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 |
| | Suppressors of yeast actin mutations | Q27929812 |
| | SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases. | Q27930732 |
| | Vacuole Size Control: Regulation of PtdIns(3,5)P2Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P2-specific Phosphatase | Q27933521 |
| | Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy | Q27933594 |
| | SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases | Q27934132 |
| | Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B | Q28116107 |
| | Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase | Q28117024 |
| | Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway | Q28117913 |
| | The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals | Q28118433 |
| | The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase | Q28118769 |
| | Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling | Q28119117 |
| | High frequency of mutations of the PIK3CA gene in human cancers | Q28131776 |
| | A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells | Q28140807 |
| | Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals | Q28212156 |
| | Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl | Q28235300 |
| | Inositol polyphosphate 4-phosphatase is inactivated by calpain-mediated proteolysis in stimulated human platelets | Q28235484 |
| | PTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolism | Q28238905 |
| | PTEN is a protein tyrosine phosphatase for IRS1 | Q28239790 |
| | A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate | Q28254402 |
| | Identification of a second SH2-domain-containing protein closely related to the phosphatidylinositol polyphosphate 5-phosphatase SHIP | Q28254532 |
| | Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases | Q28271134 |
| | A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast | Q28279868 |
| | p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity | Q28280824 |
| | Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2 | Q28285431 |
| | The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity | Q28289470 |
| | A secreted PTEN phosphatase that enters cells to alter signaling and survival | Q28292188 |
| | Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate | Q28301966 |
| | Cloning and expression of human brain type I inositol 1,4,5-trisphosphate 5-phosphatase. High levels of mRNA in cerebellar Purkinje cells | Q34328974 |
| | PTEN interacts with histone H1 and controls chromatin condensation | Q34364654 |
| | Role of synaptojanin 2 in glioma cell migration and invasion | Q34368760 |
| | The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1. | Q34408784 |
| | MORM syndrome (mental retardation, truncal obesity, retinal dystrophy and micropenis), a new autosomal recessive disorder, links to 9q34. | Q34496759 |
| | Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels | Q34512579 |
| | Removal or masking of phosphatidylinositol(4,5)bisphosphate from the outer mitochondrial membrane causes mitochondrial fragmentation | Q34548085 |
| | Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein | Q34556566 |
| | SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer | Q34629544 |
| | Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis | Q34701557 |
| | Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate | Q34719423 |
| | Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease. | Q34742581 |
| | AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer | Q34990362 |
| | Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model | Q35094438 |
| | A critical role of mitochondrial phosphatase Ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells | Q35599073 |
| | Therapeutic potential of SH2 domain-containing inositol-5'-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer | Q35718988 |
| | Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8. | Q36066328 |
| | Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function | Q36222030 |
| | Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry. | Q36285541 |
| | PTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome. | Q36361389 |
| | PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma | Q36652026 |
| | Achieving specificity in Akt signaling in cancer | Q36733736 |
| | Sequential actions of myotubularin lipid phosphatases regulate endosomal PI(3)P and growth factor receptor trafficking | Q36796937 |
| | Genotypes and phenotypes of Joubert syndrome and related disorders | Q37047187 |
| | The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures | Q37215037 |
| | Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation. | Q37375092 |
| | Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress | Q37380066 |
| | Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors | Q37549774 |
| | Phosphatidylinositol 3,4,5-trisphosphate is a substrate for the 75 kDa inositol polyphosphate 5-phosphatase and a novel 5-phosphatase which forms a complex with the p85/p110 form of phosphoinositide 3-kinase | Q37622733 |
| | Methods for analyzing phosphoinositides using mass spectrometry | Q37941424 |
| | How phosphoinositide 3-phosphate controls growth downstream of amino acids and autophagy downstream of amino acid withdrawal | Q37977162 |
| | A new approach to measuring phosphoinositides in cells by mass spectrometry. | Q38152178 |
| | The uses and limitations of the analysis of cellular phosphoinositides by lipidomic and imaging methodologies. | Q38207428 |
| | PTEN. | Q38218236 |
| | New insight into the intracellular roles of class II phosphoinositide 3-kinases. | Q38252290 |
| | Molecular basis of the recruitment of the SH2 domain-containing inositol 5-phosphatases SHIP1 and SHIP2 by fcgamma RIIB. | Q38307909 |
| | Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane | Q38409013 |
| | cDNA Microarray Analysis of Gene Expression Profiles Associated with Cervical Cancer | Q38522565 |
| | INPP4B suppresses prostate cancer cell invasion | Q38953956 |
| | cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity | Q39373761 |
| | PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity | Q39388363 |
| | Cell cycle arrest and apoptosis by expression of a novel TPIP (TPIP-C2) cDNA encoding a C2-domain in HEK-293 cells | Q39400607 |
| | The myotubularin phosphatase MTMR4 regulates sorting from early endosomes | Q39663762 |
| | Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation | Q39766760 |
| | A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. | Q40020748 |
| | Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover. | Q40076648 |
| | Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B. | Q40316731 |
| | Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. | Q40394190 |
| | Analysis of phosphoinositide binding domain properties within the myotubularin-related protein MTMR3. | Q40433158 |
| | Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death | Q40769024 |
| | FYVE-DSP2, a FYVE domain-containing dual specificity protein phosphatase that dephosphorylates phosphotidylinositol 3-phosphate | Q40812801 |
| | Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway | Q40852967 |
| | Underexpression of the 43 kDa inositol polyphosphate 5-phosphatase is associated with cellular transformation | Q41077168 |
| | Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. | Q42815905 |
| | Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1. | Q43129377 |
| | miR-508 sustains phosphoinositide signalling and promotes aggressive phenotype of oesophageal squamous cell carcinoma. | Q43416243 |
| | SnapShot: lipid kinases and phosphatases. | Q44956199 |
| | SHIP2 phosphoinositol phosphatase positively regulates EGFR-Akt pathway, CXCR4 expression, and cell migration in MDA-MB-231 breast cancer cells. | Q46198401 |
| | Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers | Q47814180 |
| | The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells | Q48362692 |
| | Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers | Q48464018 |
| | Synaptojanin is the major constitutively active phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase in rodent brain. | Q48729618 |
| | Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation | Q50335975 |
| | Application of electron conformational-genetic algorithm approach to 1,4-dihydropyridines as calcium channel antagonists: pharmacophore identification and bioactivity prediction. | Q51583668 |
| P433 | issue | 2 | |
| P304 | page(s) | 176-192 | |
| P577 | publication date | 2015-08-24 | |
| P1433 | published in | Journal of Lipid Research | Q6295449 |
| P1476 | title | Phosphatidylinositolphosphate phosphatase activities and cancer | |
| P478 | volume | 57 | |