| scholarly article | Q13442814 |
| P50 | author | Junsheng Yang | Q57321071 |
| P2093 | author name string | Xinghua Feng | |
| P2860 | cites work | Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease | Q22242985 |
| Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition | Q24307004 | ||
| Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1 | Q24310249 | ||
| NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes | Q24310567 | ||
| mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state | Q24315101 | ||
| Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis | Q24315133 | ||
| Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling | Q24316454 | ||
| NAADP mobilizes calcium from acidic organelles through two-pore channels | Q24318546 | ||
| Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction | Q24336179 | ||
| TMEM175 Is an Organelle K(+) Channel Regulating Lysosomal Function | Q24338758 | ||
| The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction | Q24603159 | ||
| TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+ | Q24621022 | ||
| Inter-organelle ER-endolysosomal contact sites in metabolism and disease across evolution | Q26739484 | ||
| Modulation of the neuronal network activity by P2X receptors and their involvement in neurological disorders | Q38540140 | ||
| Inhibition of Transient Receptor Potential Channel Mucolipin-1 (TRPML1) by Lysosomal Adenosine Involved in Severe Combined Immunodeficiency Diseases | Q38721360 | ||
| Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force | Q38754504 | ||
| A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation. | Q38788245 | ||
| Brain Disorders Due to Lysosomal Dysfunction. | Q38811324 | ||
| Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification. | Q38841488 | ||
| Poring over two-pore channel pore mutants | Q38844674 | ||
| Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes | Q38969543 | ||
| Determining the Roles of Inositol Trisphosphate Receptors in Neurodegeneration: Interdisciplinary Perspectives on a Complex Topic. | Q38988539 | ||
| Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx | Q39438967 | ||
| TRPM2 functions as a lysosomal Ca2+-release channel in beta cells | Q39849413 | ||
| Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate. | Q39990488 | ||
| BK channel agonist represents a potential therapeutic approach for lysosomal storage diseases | Q41189322 | ||
| Tuning the ion selectivity of two-pore channels | Q41779299 | ||
| Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release | Q41822869 | ||
| Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes | Q41891896 | ||
| Calcium signaling and neurodegeneration | Q42066419 | ||
| An Endosomal NAADP-Sensitive Two-Pore Ca2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling | Q42133849 | ||
| Calcium signaling in neurodegeneration | Q42199396 | ||
| Isolated pores dissected from human two-pore channel 2 are functional | Q42354590 | ||
| Endolysosomal two-pore channels regulate autophagy in cardiomyocytes. | Q42487367 | ||
| Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals | Q42959504 | ||
| pH-dependent regulation of lysosomal calcium in macrophages | Q43893449 | ||
| Neurodegenerative diseases and oxidative stress | Q44805871 | ||
| TRP channels and pain | Q46357812 | ||
| BK Channels Alleviate Lysosomal Storage Diseases by Providing Positive Feedback Regulation of Lysosomal Ca2+ Release | Q50976144 | ||
| Planar patch clamp approach to characterize ionic currents from intact lysosomes | Q51552498 | ||
| Huntington disease | Q56083219 | ||
| Gaucher disease | Q56338451 | ||
| Different types of calcium channels mediate central synaptic transmission | Q59054415 | ||
| Congenital corneal clouding with abnormal systemic storage bodies: A new variant of mucolipidosis | Q59884846 | ||
| Multiple calcium channel types control glutamatergic synaptic transmission in the hippocampus | Q72658211 | ||
| Oxidative Stress in Neurodegenerative Diseases | Q26801239 | ||
| The role of TRPMLs in endolysosomal trafficking and function | Q26864223 | ||
| Integration of modeling with experimental and clinical findings synthesizes and refines the central role of inositol 1,4,5-trisphosphate receptor 1 in spinocerebellar ataxia | Q26864714 | ||
| Lysosomal membrane proteins and their central role in physiology | Q27013815 | ||
| Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo. | Q27308929 | ||
| Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol | Q27646366 | ||
| Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein | Q27935790 | ||
| Molecular physiology of P2X receptors | Q28203477 | ||
| NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs | Q28216586 | ||
| Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases | Q28242217 | ||
| Voltage-Gated Calcium Channels | Q28242997 | ||
| High susceptibility to fatty liver disease in two-pore channel 2-deficient mice | Q28246421 | ||
| Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells | Q28260464 | ||
| Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana | Q28271341 | ||
| Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana | Q28274013 | ||
| Oxidative stress in neurodegeneration: cause or consequence? | Q28275946 | ||
| TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes | Q28276964 | ||
| Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling | Q28277133 | ||
| Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomes | Q28283147 | ||
| Transient receptor potential cation channels in disease | Q28284143 | ||
| Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organelles | Q28286984 | ||
| International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels | Q28289125 | ||
| The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel | Q28294133 | ||
| An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals | Q28294394 | ||
| Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations | Q28506710 | ||
| TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents | Q28508162 | ||
| Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1 | Q28581167 | ||
| Dendritic cell maturation and chemotaxis is regulated by TRPM2‐mediated lysosomal Ca2+release | Q28584942 | ||
| The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores | Q28585336 | ||
| Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport | Q28594812 | ||
| PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome | Q29543488 | ||
| The versatility and universality of calcium signalling | Q29547402 | ||
| TPC2 controls pigmentation by regulating melanosome pH and size | Q36931154 | ||
| The endoplasmic reticulum, not the pH gradient, drives calcium refilling of lysosomes. | Q37008566 | ||
| Calcium dysregulation in Alzheimer's disease | Q37012642 | ||
| MCOLN1 is a ROS sensor in lysosomes that regulates autophagy | Q37061225 | ||
| A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis | Q37224430 | ||
| Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons. | Q37400839 | ||
| Fusion of lysosomes with secretory organelles leads to uncontrolled exocytosis in the lysosomal storage disease mucolipidosis type IV. | Q37623318 | ||
| Endolysosomal calcium regulation and disease | Q37813734 | ||
| Vacuolar Ca(2+) uptake. | Q37839403 | ||
| Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease | Q37944859 | ||
| Neuronal P/Q-type calcium channel dysfunction in inherited disorders of the CNS. | Q37976377 | ||
| Calcium signalling remodelling and disease | Q37995715 | ||
| Lysosomal storage diseases—the horizon expands | Q38128478 | ||
| Evolution of acidic Ca²⁺ stores and their resident Ca²⁺-permeable channels | Q38319655 | ||
| Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts | Q38389995 | ||
| Inhibition of Voltage-Gated Calcium Channels by RGK Proteins | Q38475663 | ||
| Compromised autophagy and neurodegenerative diseases | Q38492623 | ||
| An introduction to TRP channels | Q29615753 | ||
| Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin | Q29616107 | ||
| Calcium signaling | Q29617338 | ||
| High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart | Q30835214 | ||
| P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH. | Q33792971 | ||
| Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum | Q33870467 | ||
| TRP channels of intracellular membranes | Q34001734 | ||
| The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy. | Q34315702 | ||
| Principles of lysosomal membrane digestion: stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids | Q34457870 | ||
| Lysosomal physiology | Q34462083 | ||
| Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment | Q34464824 | ||
| Mutations in SNX14 cause a distinctive autosomal-recessive cerebellar ataxia and intellectual disability syndrome | Q34478269 | ||
| Function and dysfunction of two-pore channels | Q34483905 | ||
| The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation | Q34583526 | ||
| Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis | Q34701623 | ||
| The molecular basis of mucolipidosis type IV. | Q34748134 | ||
| Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses | Q34831241 | ||
| Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium | Q34866369 | ||
| Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels | Q35067713 | ||
| Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels. | Q35082699 | ||
| Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation | Q35212557 | ||
| Transcriptional activation of lysosomal exocytosis promotes cellular clearance | Q35214694 | ||
| A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis | Q35219922 | ||
| Organellar channels and transporters | Q35691118 | ||
| Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion | Q35771431 | ||
| Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease | Q35912172 | ||
| Recent breakthroughs in the molecular mechanism of capacitative calcium entry (with thoughts on how we got here) | Q36002742 | ||
| Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. | Q36085273 | ||
| Drosophila TRPML is required for TORC1 activation | Q36236541 | ||
| Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model. | Q36431970 | ||
| Orai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe. | Q36485197 | ||
| Intracellular sphingosine releases calcium from lysosomes | Q36552660 | ||
| Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB. | Q36709792 | ||
| Phosphatidylinositol 3,5-bisphosphate: regulation of cellular events in space and time | Q36812142 | ||
| Lysosomes: fusion and function | Q36885390 | ||
| P433 | issue | 1-2 | |
| P921 | main subject | neurodegeneration | Q1755122 |
| P304 | page(s) | 56-66 | |
| P577 | publication date | 2016-06-01 | |
| P1433 | published in | Messenger (Los Angeles, Calif. : Print) | Q27724829 |
| P1476 | title | Lysosomal Calcium in Neurodegeneration | |
| P478 | volume | 5 |
Search more.