| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1039/B610213C |
| P698 | PubMed publication ID | 18197348 |
| P50 | author | Véronique Gouverneur | Q21716261 |
| P2093 | author name string | Peter R Moore | |
| Sophie Purser | |||
| Steve Swallow | |||
| P433 | issue | 2 | |
| P304 | page(s) | 320-330 | |
| P577 | publication date | 2007-12-13 | |
| P1433 | published in | Chemical Society Reviews | Q2962268 |
| P1476 | title | Fluorine in medicinal chemistry | |
| P478 | volume | 37 |
| Q35436652 | (2R)-N-(2-Benzoyl-phen-yl)-1-benzyl-pyrrolidine-2-carboxamide |
| Q57496002 | -C-H arylation of fluoroarenes traceless directing group relay strategy |
| Q36280536 | 1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase |
| Q41859230 | 2,2,2-Tri-fluoro-N-(2-iodo-phen-yl)acetamide |
| Q58878049 | 2,4-Bis(fluoroalkyl)quinoline-3-carboxylates as Tools for the Development of Potential Agrochemical Ingredients |
| Q42150661 | 2-Diazo-1-phenyl-2-((trifluoromethyl)sulfonyl)ethan-1-one: Another Utility for Electrophilic Trifluoromethylthiolation Reactions |
| Q89289670 | 3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation |
| Q27728066 | 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors |
| Q89719816 | 5-Trifluoromethyl-2-formylphenylboronic Acid |
| Q64032901 | A Biocatalytic Platform for Synthesis of Chiral Trifluoromethylated Organoborons |
| Q58568483 | A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates |
| Q82226144 | A Facile and Stereocontrolled Synthesis of γ-Substituted γ-Fluoroglutamates by Conjugate Addition: Conflicting Effect between Fluorinated Enaminoester and Hinderered Michael Acceptor |
| Q36486950 | A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides |
| Q90754315 | A Gas Phase Route to [18F]fluoroform with Limited Molar Activity Dilution |
| Q58878159 | A General Approach to (Trifluoromethoxy)pyridines: First X-ray Structure Determinations and Quantum Chemistry Studies |
| Q58878096 | A General Approach towards NH-Pyrazoles That Bear Diverse Fluoroalkyl Groups by Means of Fluorinated Iminium Salts |
| Q58878122 | A New Life for an Old Reagent: Fluoroalkyl Amino Reagents as Efficient Tools for the Synthesis of Diversely Fluorinated Pyrazoles |
| Q30827768 | A Novel Non-Peptidic Agonist of the Ghrelin Receptor with Orexigenic Activity In vivo |
| Q90523269 | A Short and Efficient Total Synthesis of Ficuseptamines A and B |
| Q46441354 | A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging |
| Q41909168 | A broadly applicable copper reagent for trifluoromethylations and perfluoroalkylations of aryl iodides and bromides |
| Q42544866 | A catalytic borylation/dehalogenation route to o-fluoro arylboronates |
| Q39035856 | A fluorinated dendrimer achieves excellent gene transfection efficacy at extremely low nitrogen to phosphorus ratios |
| Q36591442 | A general preparation of (Z)-1-fluorostilbene derivatives for the design of conformationally restricted peptidomimetics |
| Q42549258 | A general strategy for the perfluoroalkylation of arenes and arylbromides by using arylboronate esters and [(phen)CuR(F)] |
| Q42597853 | A general, enantioselective synthesis of β- and γ-fluoroamines |
| Q35966796 | A highly regio- and stereoselective synthesis of α-fluorinated imides via fluorination of chiral enamides |
| Q64988366 | A new method for production of chiral 2-aryl-2-fluoropropanoic acids using an effective kinetic resolution of racemic 2-aryl-2-fluoropropanoic acids. |
| Q54942282 | A practical microwave method for the synthesis of fluoromethy 4-methylbenzenesulfonate in tert-amyl alcohol. |
| Q34266733 | A simple method for asymmetric trifluoromethylation of N-acyl oxazolidinones via Ru-catalyzed radical addition to zirconium enolates |
| Q59125172 | A third generation of radical fluorinating agents based on N-fluoro-N-arylsulfonamides |
| Q39505737 | ATP-Dependent C-F Bond Cleavage Allows the Complete Degradation of 4-Fluoroaromatics without Oxygen |
| Q35920329 | Accelerating palladium-catalyzed C-F bond formation: use of a microflow packed-bed reactor |
| Q48275473 | Achieving regio- and stereo-control in the fluorination of aziridines under acidic conditions. |
| Q89571310 | Activation of Aromatic C-F Bonds by a N-Heterocyclic Olefin (NHO) |
| Q38261980 | Advances in catalytic enantioselective fluorination, mono-, di-, and trifluoromethylation, and trifluoromethylthiolation reactions |
| Q48254161 | Alkene 1,2-Difunctionalization by Radical Alkenyl Migration |
| Q40540297 | Aminodifluorosulfinium salts: selective fluorination reagents with enhanced thermal stability and ease of handling |
| Q37381023 | An improved catalyst system for the Pd-catalyzed fluorination of (hetero)aryl triflates |
| Q36658019 | An organocatalytic strategy for the stereoselective synthesis of C-galactosides with fluorine at the pseudoanomeric carbon |
| Q43225606 | An unexpected and significantly lower hydrogen-bond-donating capacity of fluorohydrins compared to nonfluorinated alcohols. |
| Q42868853 | Anion-Dependent Switch in C-X Reductive Elimination Diastereoselectivity. |
| Q57258194 | Anion-Initiated Trifluoromethylation by TMSCF: Deconvolution of the Siliconate-Carbanion Dichotomy by Stopped-Flow NMR/IR |
| Q43131327 | Antimicrobial and anticancer activity of some novel fluorinated thiourea derivatives carrying sulfonamide moieties: synthesis, biological evaluation and molecular docking |
| Q31114482 | Application of palladium-mediated (18)F-fluorination to PET radiotracer development: overcoming hurdles to translation |
| Q38637720 | Application of the Pentafluorosulfanyl Group as a Bioisosteric Replacement |
| Q61852499 | Applications of liquid chromatography-inductively coupled plasma-mass spectrometry in the biosciences: A tutorial review and recent developments |
| Q41991312 | Approaches to the chemical synthesis of the chlorosulfolipids |
| Q57037470 | Aqueous Benzylic C-H Trifluoromethylation for Late-Stage Functionalization |
| Q90178850 | Aromatic Fluorination of Multiblock Amphiphile Enhances Its Incorporation into Lipid Bilayer Membranes |
| Q41174141 | Asymmetric 18F-fluorination for applications in positron emission tomography |
| Q42955582 | Asymmetric NHC-catalyzed synthesis of α-fluoroamides from readily accessible α-fluoroenals |
| Q36886848 | Asymmetric catalytic Mannich-type reaction of hydrazones with difluoroenoxysilanes using imidazoline-anchored phosphine ligand-zinc(II) complexes. |
| Q42765042 | Asymmetric fluorination of α-branched cyclohexanones enabled by a combination of chiral anion phase-transfer catalysis and enamine catalysis using protected amino acids |
| Q38582683 | Asymmetric palladium-catalyzed directed intermolecular fluoroarylation of styrenes |
| Q50865085 | Asymmetric silver-catalysed intermolecular bromotrifluoromethoxylation of alkenes with a new trifluoromethoxylation reagent. |
| Q54482137 | Aza-Henry Reactions on C-Alkyl Substituted Aldimines. |
| Q40961509 | Barbier-type anti-Diastereo- and Enantioselective Synthesis of β-Trimethylsilyl, Fluorinated Methyl, Phenylthio Homoallylic Alcohols |
| Q46761871 | Base-catalyzed diastereoselective trimerization of trifluoroacetone |
| Q58716687 | Benzoate Cyclometalation Enables Oxidative Addition of Haloarenes at a Ru(II) Center |
| Q63436537 | Bifunctional Chiral Quaternary Ammonium Salt Catalysts: A Rapidly Emerging Class of Powerful Asymmetric Catalysts |
| Q42034665 | Biocatalytic trifluoromethylation of unprotected phenols |
| Q95561493 | Bis(pentafluorosulfanyl)phenyl azide as an expeditious tool for click chemistry toward antitumor pharmaceuticals |
| Q48294489 | C(sp2)-H Borylation of Fluorinated Arenes Using an Air-Stable Cobalt Precatalyst: Electronically Enhanced Site Selectivity Enables Synthetic Opportunities. |
| Q41974943 | C-F Bond Formation for the Synthesis of Aryl Fluorides |
| Q51579508 | Can acyclic conformational control be achieved via a sulfur-fluorine gauche effect? |
| Q92133014 | Cascade trifluoromethylthiolation and cyclization of N-[(3-aryl)propioloyl]indoles |
| Q27687352 | Catalysis for fluorination and trifluoromethylation |
| Q64062981 | Catalytic Asymmetric Fluorination of Alkyl 1-indanone-2-carboxylates Ruled by Pybox-Eu(III) Combination |
| Q92511361 | Catalytic Asymmetric Fluorination of Copper Carbene Complexes: Preparative Advances and a Mechanistic Rationale |
| Q36814127 | Catalytic Asymmetric Mannich Reactions with Fluorinated Aromatic Ketones: Efficient Access to Chiral β-Fluoroamines |
| Q88187121 | Catalytic Diastereo- and Enantioselective Fluoroamination of Alkenes |
| Q42055076 | Catalytic Intramolecular Aminofluorination, Oxyfluorination, and Carbofluorination with a Stable and Versatile Hypervalent Fluoroiodine Reagent. |
| Q42152537 | Catalytic Nucleophilic Fluorination of Secondary and Tertiary Propargylic Electrophiles with a Copper-N-Heterocyclic Carbene Complex |
| Q37733829 | Catalytic asymmetric radical aminoperfluoroalkylation and aminodifluoromethylation of alkenes to versatile enantioenriched-fluoroalkyl amines |
| Q41919518 | Catalytic asymmetric synthesis of CF3-substituted tertiary propargylic alcohols via direct aldol reaction of α-N3 amide |
| Q36554570 | Catalytic enantioselective cyclization and C3-fluorination of polyenes. |
| Q92278337 | Catalytic enantioselective synthesis of perfluoroalkyl-substituted β-lactones via a concerted asynchronous [2 + 2] cycloaddition: a synthetic and computational study |
| Q64275492 | Catalytic radical difluoromethoxylation of arenes and heteroarenes |
| Q42373498 | Catalytic, Diastereoselective 1,2-Difluorination of Alkenes |
| Q41678703 | Catalytic, asymmetric difluorination of alkenes to generate difluoromethylated stereocenters |
| Q42714607 | Catalytic, asymmetric reactions of ketenes and ketene enolates. |
| Q92625479 | Catalyzing the Hydrodefluorination of CF3-Substituted Alkenes by PhSiH3. H• Transfer from a Nickel Hydride |
| Q41951098 | Cation versus Radical: Studies on the C/O Regioselectivity in Electrophilic Tri-, Di- and Monofluoromethylations of β-Ketoesters |
| Q87088524 | Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs |
| Q35248736 | Chemical probes for the functionalization of polyketide intermediates |
| Q36740938 | Chemoenzymatic synthesis of mono- and di-fluorinated Thomsen-Friedenreich (T) antigens and their sialylated derivatives. |
| Q48181907 | Chlorodifluoromethane-triggered formation of difluoromethylated arenes catalysed by palladium |
| Q53130318 | Concise Xanthine Synthesis through a Double-Amidination Reaction of a 6-Chlorouracil with Amidines using Base-Metal Catalysis. |
| Q95819988 | Contribution of Organofluorine Compounds to Pharmaceuticals |
| Q91710062 | Controlled chemoselective defluorination and non-defluorination for [5 + 1] aromatic annulation via Meisenheimer-type nitrogen anion and radical intermediates |
| Q89070105 | Controlling Pd(IV) reductive elimination pathways enables Pd(II)-catalysed enantioselective C(sp3)-H fluorination |
| Q85924093 | Cooperative dual palladium/silver catalyst for direct difluoromethylation of aryl bromides and iodides |
| Q36549456 | Copper-Catalyzed Aerobic C-H Trifluoromethylation of Phenanthrolines. |
| Q59071327 | Copper-Catalyzed Innate Ethoxycarbonyldifluoromethylation of Electron-Rich Arenes |
| Q42748953 | Copper-Catalyzed Synthesis of Trifluoroethylarenes from Benzylic Bromodifluoroacetates |
| Q59071349 | Copper-Mediated Synthesis of Aryldifluoromethylphosphonates: A Sandmeyer Approach |
| Q59071245 | Copper-Mediated [(Diethylphosphono)difluoromethyl]thiolation of α-Bromo Ketones |
| Q35065352 | Copper-catalyzed arylation of 1H-perfluoroalkanes |
| Q36165294 | Copper-catalyzed oxytrifluoromethylation of unactivated alkenes. |
| Q37406227 | Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent |
| Q37069922 | Copper-catalyzed, directing group-assisted fluorination of arene and heteroarene C-H bonds |
| Q38861143 | Copper-mediated perfluoroalkylation of heteroaryl bromides with (phen)CuRF. |
| Q41862668 | Copper-mediated radical trifluoromethylation of unsaturated potassium organotrifluoroborates |
| Q41810243 | Crystal structure of 1-methyl-3-[2,2,2-tri-fluoro-1-(1-methyl-1H-indol-3-yl)-1-phenyl-eth-yl]-1H-indole |
| Q36440495 | Crystal structure of [bis-(2-amino-ethyl-κN)(2-{[4-(tri-fluoro-meth-yl)benzyl-idene]amino}-eth-yl)amine-κN]di-chlorido-copper(II). |
| Q59907181 | Cu and Hydroquinone for the Trifluoromethylation of Unprotected Phenols |
| Q41110557 | Cu-Mediated C-H 18F-Fluorination of Electron-Rich (Hetero)arenes |
| Q33894916 | Cu-catalyzed fluorination of diaryliodonium salts with KF. |
| Q60240364 | CuI-Mediated Trifluoromethylations with Stannanes. Preliminary Communication |
| Q40989455 | DBFOX-Ph/metal complexes: evaluation as catalysts for enantioselective fluorination of 3-(2-arylacetyl)-2-thiazolidinones. |
| Q34472165 | Decarboxylative Fluorination of Aliphatic Carboxylic Acids via Photoredox Catalysis |
| Q88652370 | Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids |
| Q59932216 | Deconstructive fluorination of cyclic amines by carbon-carbon cleavage |
| Q35017577 | Design and generation of highly diverse fluorinated fragment libraries and their efficient screening with improved (19) F NMR methodology |
| Q47990815 | Design and synthesis of new N-(5-trifluoromethyl)-1H-1,2,4-triazol-3-yl benzenesulfonamides as possible antimalarial prototypes |
| Q35569236 | Design of gem-difluoro-bis-tetrahydrofuran as P2 ligand for HIV-1 protease inhibitors to improve brain penetration: synthesis, X-ray studies, and biological evaluation |
| Q90632764 | Design, Synthesis and Biological Evaluation of Jahanyne Analogs as Cell Cycle Arrest Inducers |
| Q96111927 | Desymmetrization of difluoromethylene groups by C-F bond activation |
| Q36032683 | Development of a novel class of glucose transporter inhibitors |
| Q90609893 | Development of copper-catalyzed enantioselective decarboxylative aldolization for the preparation of perfluorinated 1,3,5-triols featuring supramolecular recognition properties |
| Q42862597 | Diastereoselective Silver-Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with Fluorinated Imine |
| Q59071577 | Diethylzinc-Mediated Addition of 2,2-Dibromo-2-fluoroacetamides to Carbonyl Compounds: Synthesis of α-Bromo-α-fluoro-β-hydroxy Amides and/or (Z)-Fluorovinyl Amides |
| Q37619469 | Difluoro-and Trifluoromethylation of Electron-Deficient Alkenes in an Electrochemical Microreactor |
| Q28601782 | Difluoromethanesulfonyl hypervalent iodonium ylides for electrophilic difluoromethylthiolation reactions under copper catalysis |
| Q41030476 | Direct Access to β-Fluorinated Aldehydes by Nitrite-Modified Wacker Oxidation. |
| Q89474610 | Direct C-H difluoromethylation of heterocycles via organic photoredox catalysis |
| Q59071360 | Direct Vicinal Difunctionalization of Alkynes: An Efficient Approach Towards the Synthesis of Highly Functionalized Fluorinated Alkenes |
| Q89465874 | Direct and Chemoselective Electrophilic Monofluoromethylation of Heteroatoms (O-, S-, N-, P-, Se-) with Fluoroiodomethane |
| Q42782478 | Direct electrophilic N-trifluoromethylthiolation of amines with trifluoromethanesulfenamide. |
| Q64924481 | Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives. |
| Q96126815 | Direct transfer of tri- and di-fluoroethanol units enabled by radical activation of organosilicon reagents |
| Q33636171 | Discovery of a Novel Class of Imidazo[1,2-a]Pyridines with Potent PDGFR Activity and Oral Bioavailability |
| Q41664519 | Divergent reactivities in fluoronation of allylic alcohols: synthesis of Z-fluoroalkenes via carbon-carbon bond cleavage. |
| Q42386371 | Dual C-F, C-H Functionalization via Photocatalysis: Access to Multifluorinated Biaryls |
| Q41865618 | Effective synthesis of chiral N-fluoroaryl aziridines through enantioselective aziridination of alkenes with fluoroaryl azides. |
| Q48907584 | Efficient Synthesis of Trifluoromethyl Amines through a Formal Umpolung Strategy from the Bench-Stable Precursor (Me4 N)SCF3. |
| Q100380176 | Efficient Synthesis of Trifluoromethylated Purine Ribonucleosides and Ribonucleotides |
| Q42239696 | Efficient regio- and stereoselective access to novel fluorinated β-aminocyclohexanecarboxylates |
| Q47756513 | Electrifying Organic Synthesis. |
| Q93048310 | Electrochemical Flash Fluorination and Radiofluorination |
| Q41572370 | Electrochemical Fluorination and Radiofluorination of Methyl(phenylthio)acetate Using Tetrabutylammonium Fluoride (TBAF). |
| Q92241106 | Electrophotocatalytic Undirected C-H Trifluoromethylations of (Het)Arenes |
| Q60401552 | Enantiodivergent Approach to Trifluoromethylated Amines: A Concise Route to Both Enantiomeric Analogues of Calcimimetic NPS R-568 |
| Q92678644 | Enantiodivergent α-Amino C-H Fluoroalkylation Catalyzed by Engineered Cytochrome P450s |
| Q92316503 | Enantioselective Benzylation and Allylation of α-Trifluoromethoxy Indanones under Phase-Transfer Catalysis |
| Q41991899 | Enantioselective Synthesis of Fluoro-Dihydroquinazolones and -Benzooxazinones by Fluorination-Initiated Asymmetric Cyclization Reactions |
| Q48974117 | Enantioselective Synthesis of β-Fluoro Amines via β-Amino α-Fluoro Nitroalkanes and a Traceless Activating Group Strategy. |
| Q87321537 | Enantioselective aldol reactions with masked fluoroacetates |
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| Q91904148 | Enantioselective construction of remote tertiary carbon-fluorine bonds |
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| Q44154856 | Engineered Fluorine Metabolism and Fluoropolymer Production in Living Cells |
| Q82998044 | Engineering fluorination |
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| Q35967391 | Evidence for in situ catalyst modification during the Pd-catalyzed conversion of aryl triflates to aryl fluorides |
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| Q42122693 | Expedient synthesis of α-substituted fluoroethenes. |
| Q83365711 | Facile stereoslective synthesis of spiro[indole-oxiranes] by combination of phase transfer catalyst and ultrasound irradiation and their bioassay |
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| Q41230961 | Fluorinated Amine Stereotriads via Allene Amination. |
| Q93107280 | Fluorinated compounds present opportunities for drug discovery |
| Q92431431 | Fluorinated synthetic anion carriers: experimental and computational insights into transmembrane chloride transport |
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| Q61066401 | Fluorine Scan of Inhibitors of the Cysteine Protease Human Cathepsin L: Dipolar and Quadrupolar Effects in the π-Stacking of Fluorinated Phenyl Rings on Peptide Amide Bonds |
| Q39779987 | Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical Properties |
| Q49802220 | Fluorine teams up with water to restore inhibitor activity to mutant BPTI. |
| Q64241260 | Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs |
| Q52559376 | Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis. |
| Q41889942 | Fluorine-decoupled carbon spectroscopy for the determination of configuration at fully substituted, trifluoromethyl- and perfluoroalkyl-bearing carbons: comparison with 19F-1H heteronuclear Overhauser effect spectroscopy |
| Q42099161 | Fluorine-rich planetary environments as possible habitats for life |
| Q30396809 | Fluorine–Protein Interactions and 19F NMR Isotropic Chemical Shifts: An Empirical Correlation with Implications for Drug Design |
| Q35775999 | Fluoro-substituted ketones from nitriles using acidic and basic reaction conditions |
| Q39366624 | Fluoroalkyl Amino Reagents (FARs): A General Approach towards the Synthesis of Heterocyclic Compounds Bearing Emergent Fluorinated Substituents |
| Q46113351 | Fluorothreonyl-tRNA deacylase prevents mistranslation in the organofluorine producer Streptomyces cattleya |
| Q47843515 | Forbidden Coherence Transfer of 19F Nuclei to Quantitatively Measure the Dynamics of a CF₃-Containing Ligand in Receptor-Bound States |
| Q42703521 | Forging Fluorine-Containing Quaternary Stereocenters by a Light-Driven Organocatalytic Aldol Desymmetrization Process |
| Q42322495 | From bifunctional to trifunctional (tricomponent nucleophile-transition metal-lewis acid) catalysis: the catalytic, enantioselective α-fluorination of acid chlorides |
| Q92823869 | Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides |
| Q55432495 | HIV-Associated Neurocognitive Disorder (HAND) and the Prospect of Brain-Penetrating Protease Inhibitors for Antiretroviral Treatment. |
| Q90113407 | High-Valent NiIII and NiIV Species Relevant to C-C and C-Heteroatom Cross-Coupling Reactions: State of the Art |
| Q35031125 | Highly selective electrochemical fluorination of dithioacetal derivatives bearing electron-withdrawing substituents at the position α to the sulfur atom using poly(HF) salts |
| Q45469190 | Highly selective nickel-catalyzed gem-difluoropropargylation of unactivated alkylzinc reagents |
| Q33926500 | How cinchona alkaloid-derived primary amines control asymmetric electrophilic fluorination of cyclic ketones |
| Q42163193 | Hydrofluorination of Alkynes Catalysed by Gold Bifluorides |
| Q48181503 | Hydrogen Bond Directed Photocatalytic Hydrodefluorination: Overcoming Electronic Control. |
| Q47763611 | Hydrogen Bonding: Regulator for Nucleophilic Fluorination. |
| Q37595127 | Identification of fipronil metabolites by time-of-flight mass spectrometry for application in a human exposure study |
| Q39156621 | Importance of the 6'-hydroxy group and its configuration for apramycin activity |
| Q38931003 | In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi. |
| Q30468232 | In vitro microbiological evaluation of 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1H-pyrazole-5,1-(4H,5H)-diyl))diethanones, novel bisacetylated pyrazoles |
| Q36763761 | In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides |
| Q35938005 | Influence of Fluorination on the Conformational Properties and Hydrogen-Bond Acidity of Benzyl Alcohol Derivatives. |
| Q42590927 | Influence of fluorocarbon and hydrocarbon acyl groups at the surface of bovine carbonic anhydrase II on the kinetics of denaturation by sodium dodecyl sulfate |
| Q42197456 | Insight into the Binding Mode of Agonists of the Nicotinic Acetylcholine Receptor from Calculated Electron Densities |
| Q27671769 | Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands |
| Q58699405 | Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay |
| Q40213630 | Investigating the Influence of (Deoxy)fluorination on the Lipophilicity of Non-UV-Active Fluorinated Alkanols and Carbohydrates by a New log P Determination Method. |
| Q37601686 | Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors |
| Q42663083 | Investigations into Transition Metal Catalyzed Arene Trifluoromethylation Reactions |
| Q45929022 | Ketones as directing groups in photocatalytic sp3 C-H fluorination. |
| Q91904140 | Kinetic modulation of graphene growth by fluorine through spatially confined decomposition of metal fluorides |
| Q37374082 | Late Stage Azidation of Complex Molecules |
| Q28088592 | Late-Stage Fluorination: From Fundamentals to Application |
| Q41154032 | Late-stage deoxyfluorination of alcohols with PhenoFluor |
| Q36663342 | Lewis acid-assisted isotopic 18F-19F exchange in BODIPY dyes: facile generation of positron emission tomography/fluorescence dual modality agents for tumor imaging |
| Q41569009 | LiTMP Trans-Metal-Trapping of Fluorinated Aromatic Molecules: A Comparative Study of Aluminum and Gallium Carbanion Traps |
| Q34631578 | Library construction and biological evaluation of enmein-type diterpenoid analogues as potential anticancer agents |
| Q42015434 | Ligand-Enabled Stereoselective β-C(sp(3))-H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids |
| Q39973971 | Mechanism of C-F reductive elimination from palladium(IV) fluorides |
| Q55364245 | Mechanisms and applications of cyclometalated Pt(ii) complexes in photoredox catalytic trifluoromethylation. |
| Q90267220 | Mechanistic Features in Al(I)-Mediated Oxidative Addition of Aryl C-F Bonds: Insights From Density Functional Theory Calculations |
| Q34987089 | Mechanistic and computational studies of oxidatively-induced aryl-CF3 bond-formation at Pd: rational design of room temperature aryl trifluoromethylation |
| Q39864568 | Mechanistic studies on intramolecular C-H trifluoromethoxylation of (hetero)arenes via OCF3-migration |
| Q93051148 | Medicinal Plant Analysis: A Historical and Regional Discussion of Emergent Complex Techniques |
| Q42269023 | Merging visible-light photocatalysis and transition-metal catalysis in the copper-catalyzed trifluoromethylation of boronic acids with CF3I. |
| Q54939432 | Metabolism and hydrophilicity of the polarised 'Janus face' all-cis tetrafluorocyclohexyl ring, a candidate motif for drug discovery. |
| Q55317571 | Metal-Mediated Halogen Exchange in Aryl and Vinyl Halides: A Review. |
| Q45299363 | Metal-free 18F-labeling of aryl-CF2H via nucleophilic radiofluorination and oxidative C-H activation |
| Q33640571 | Metal-free C-H alkylation of heteroarenes with alkyltrifluoroborates: a general protocol for 1°, 2° and 3° alkylation |
| Q92748048 | Metal-free defluorinative arylation of trifluoromethyl alkenes via photoredox catalysis |
| Q90686384 | Metallaphotoredox Difluoromethylation of Aryl Bromides |
| Q101464199 | Metallaphotoredox Perfluoroalkylation of Organobromides |
| Q41484335 | Mild silver-mediated geminal difluorination of styrenes using an air- and moisture-stable fluoroiodane reagent |
| Q38418361 | Molecular structure-optical property relationships for a series of non-centrosymmetric two-photon absorbing push-pull triarylamine molecules |
| Q38430718 | Multigram-scale Synthesis of Enantiopure 3,3-Difluoroproline |
| Q39644073 | N-Heterocyclic carbene catalyzed asymmetric hydration: direct synthesis of alpha-protio and alpha-deuterio alpha-chloro and alpha-fluoro carboxylic acids |
| Q89940843 | New sulfuryl fluoride-derived alkylating reagents for the 1,1-dihydrofluoroalkylation of thiols |
| Q41928981 | New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents. |
| Q91667123 | Nickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes with reductive decarboxylation of redox-active esters |
| Q42549745 | Nickel-catalyzed borylation of halides and pseudohalides with tetrahydroxydiboron [B2(OH)4] |
| Q46184383 | Nickel-catalyzed transamidation of aliphatic amide derivatives. |
| Q51596574 | Novel Polycarbo-Substituted Imidazo[1,2-c]quinazolines: Synthesis and Cytotoxicity Study. |
| Q89883073 | Nucleophilic Addition of Benzylboronates to Activated Ketones |
| Q89582417 | Nucleophilic trifluoromethoxylation of alkyl halides without silver |
| Q64028285 | Olefination of Alkyl Halides with Aldehydes by Merging Visible-Light Photoredox Catalysis and Organophosphorus Chemistry |
| Q90568670 | One-Pot Metal-Free Synthesis of 3-CF3-1,3-Oxazinopyridines by Reaction of Pyridines with CF3CO-Acetylenes |
| Q59167238 | One-Pot Sequential Photoredox Chemistry and Asymmetric Transfer Hydrogenation with a Single Catalyst |
| Q58721834 | One-pot aminobenzylation of aldehydes with toluenes |
| Q46150110 | One-pot multistep mechanochemical synthesis of fluorinated pyrazolones |
| Q91487865 | Open-Shell Fluorination of Alkyl Bromides: Unexpected Selectivity in a Silyl Radical-Mediated Chain Process |
| Q35523730 | Optimization of propafenone analogues as antimalarial leads |
| Q42221157 | Optimization of small-molecule inhibitors of influenza virus polymerase: from thiophene-3-carboxamide to polyamido scaffolds |
| Q39786216 | Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning |
| Q52641759 | Organic synthesis provides opportunities to transform drug discovery. |
| Q42925133 | Organocatalytic Asymmetric Synthesis of Chiral Pyrrolizines by Cascade Conjugate Addition−Aldol Reactions |
| Q34158268 | Organocatalytic enantioselective olefin aminofluorination |
| Q41828750 | Organocatalyzed Trifluoromethylation of Ketones and Sulfonyl Fluorides by Fluoroform under a Superbase System |
| Q51778113 | Organofluorine Isoselenocyanate Analogues of Sulforaphane: Synthesis and Anticancer Activity. |
| Q37587813 | Organofluorine chemistry: Difluoromethylene motifs spaced 1,3 to each other imparts facial polarity to a cyclohexane ring. |
| Q42154307 | Oxidative 3,3,3-trifluoropropylation of arylaldehydes. |
| Q37678426 | Oxidative aliphatic C-H fluorination with manganese catalysts and fluoride ion |
| Q92426447 | Oxidative allene amination for the synthesis of nitrogen-containing heterocycles |
| Q59071306 | Palladium-Catalysed Synthesis of α-(Trifluoromethyl)styrenes by Means of Directed C-H Bond Functionalization |
| Q52685848 | Palladium-Catalyzed Decarbonylative Trifluoromethylation of Acid Fluorides. |
| Q46495211 | Palladium-Catalyzed Fluorination of Cyclic Vinyl Triflates: Effect of TESCF3 as an Additive |
| Q61971329 | Palladium-Catalyzed Selective Synthesis of Perfluoroalkylated Enynes from Perfluoroalkyl Iodides and Alkynes |
| Q91635772 | Palladium-catalyzed coupling reactions on functionalized 2-trifluoromethyl-4-chromenone scaffolds. Synthesis of highly functionalized trifluoromethyl-heterocycles |
| Q41671171 | Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides. |
| Q55634749 | Palladium-catalyzed difluoromethylthiolation of heteroaryl bromides, iodides, triflates and aryl iodides. |
| Q36147885 | Palladium-catalyzed enantioselective 1,1-fluoroarylation of aminoalkenes. |
| Q35259134 | Palladium-catalyzed intramolecular C-H difluoroalkylation: synthesis of substituted 3,3-difluoro-2-oxindoles |
| Q59071165 | Pd-Catalyzed Trifluoromethylthiolation of Unsaturated Compounds: A General Approach |
| Q42134444 | Pd-catalyzed C-H fluorination with nucleophilic fluoride |
| Q54948512 | Pd-catalyzed asymmetric hydrogenation of fluorinated aromatic pyrazol-5-ols via capture of active tautomers. |
| Q37637811 | Pd-catalyzed nucleophilic fluorination of aryl bromides |
| Q41990532 | Pd-catalyzed α-arylation of trimethylsilyl enolates of α,α-difluoroacetamides |
| Q38736425 | Pd-catalyzed α-arylation of α,α-difluoroketones with aryl bromides and chlorides. A route to difluoromethylarenes |
| Q36142192 | Pentafluorosulfanyl-containing flufenamic acid analogs: Syntheses, properties and biological activities |
| Q45935901 | Perfluoroalkylation of Aryl-N,N-dimethyl Hydrazones Using Hypervalent Iodine(III) Reagents or Perfluoroalkyl Iodides. |
| Q64989230 | Phosphatase CDC25B Inhibitors Produced by Basic Alumina-Supported One-Pot Gram-Scale Synthesis of Fluorinated 2-Alkylthio-4-aminoquinazolines Using Microwave Irradiation. |
| Q40555683 | Photo-organocatalytic Enantioselective Perfluoroalkylation of β-Ketoesters. |
| Q49339054 | Photocatalytic C-F Reduction and Functionalization |
| Q48345967 | Photoinduced Remote Functionalisations by Iminyl Radical Promoted C-C and C-H Bond Cleavage Cascades. |
| Q42096518 | Photoredox catalysis: a mild, operationally simple approach to the synthesis of α-trifluoromethyl carbonyl compounds. |
| Q99579148 | Photosensitized direct C-H fluorination and trifluoromethylation in organic synthesis |
| Q42403853 | Practical and innate carbon-hydrogen functionalization of heterocycles |
| Q42123910 | Practical method for the Cu-mediated trifluoromethylation of arylboronic acids with CF3 radicals derived from NaSO2CF3 and tert-butyl hydroperoxide (TBHP). |
| Q55481533 | Prediction of 19F NMR Chemical Shifts for Fluorinated Aromatic Compounds. |
| Q59310247 | Preparation of 9α-Fluorinated Sesquiterpenic Drimanes and Evaluation of Their Antifeedant Activities |
| Q36697709 | Preparation of o-Fluorophenols from Nonaromatic Precursors: Mechanistic Considerations for Adaptation to Fluorine-18 Radiolabeling |
| Q49740389 | Progress in copper-catalyzed trifluoromethylation |
| Q47726315 | Promiscuous Defluorinating Enoyl-CoA Hydratases/Hydrolases Allow for Complete Anaerobic Degradation of 2-Fluorobenzoate |
| Q82410435 | Property and Reactivity of Fluoro(silyl)acetylenes and Fluoro(stannyl)acetylenes |
| Q60953754 | Quantitative Assessment of rPM6 for Fluorine- and Chlorine-Containing Metal Complexes: Comparison with Experimental, First-Principles, and Other Semiempirical Results |
| Q91657582 | Quantum Chemical Lipophilicities of Antimalarial Drugs in Relation to Terminal Half-Life |
| Q61943020 | Quinidine-Catalysed Enantioselective Synthesis of 6- and 4-Trifluoromethyl-Substituted Dihydropyrans |
| Q88948866 | Radical Chlorodifluoromethylation: Providing a Motif for (Hetero)arene Diversification |
| Q102369571 | Radiosynthesis of [18F]SiFAlin-TATE for clinical neuroendocrine tumor positron emission tomography |
| Q52599217 | Radiosynthesis of the anticancer nucleoside analogue Trifluridine using an automated 18F-trifluoromethylation procedure. |
| Q55021811 | Rapid access to diverse, trifluoromethyl-substituted alkenes using complementary strategies. |
| Q46093462 | Rapid access to β-trifluoromethyl-substituted ketones: harnessing inductive effects in Wacker-type oxidations of internal alkenes. |
| Q37418628 | Rapid and efficient trifluoromethylation of aromatic and heteroaromatic compounds using potassium trifluoroacetate enabled by a flow system |
| Q37446492 | Rapid cycloaddition of a diazo group with an unstrained dipolarophile |
| Q87624590 | Rapid trifluoromethylation and perfluoroalkylation of five-membered heterocycles by photoredox catalysis in continuous flow |
| Q36096683 | Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand Complexes |
| Q64067588 | Recent Advances for the Direct Introduction of the CFMe Moiety |
| Q92582415 | Recent Development of Catalytic Trifluoromethoxylation Reactions |
| Q37406266 | Recent advances in transition metal-catalyzed Csp(2)-monofluoro-, difluoro-, perfluoromethylation and trifluoromethylthiolation |
| Q90618746 | Recent advances in transition-metal-catalyzed incorporation of fluorine-containing groups |
| Q90380407 | Recent developments in photoredox-catalyzed remote ortho and para C-H bond functionalizations |
| Q55339854 | Redox-ligand sustains controlled generation of CF3 radicals by well-defined copper complex. |
| Q42157743 | Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates |
| Q101133084 | Regioselective Markovnikov hydrodifluoroalkylation of alkenes using difluoroenoxysilanes |
| Q87429316 | Regioselective trifluoromethylation of N-heteroaromatic compounds using trifluoromethyldifluoroborane activator |
| Q35598226 | Removal of Metabolic Liabilities Enables Development of Derivatives of Procaspase-Activating Compound 1 (PAC-1) with Improved Pharmacokinetics |
| Q34264792 | Replacing conventional carbon nucleophiles with electrophiles: nickel-catalyzed reductive alkylation of aryl bromides and chlorides |
| Q41640907 | Rhodium-Catalyzed Geminal Oxyfluorination and Oxytrifluoro-Methylation of Diazocarbonyl Compounds. |
| Q36266419 | Room temperature copper(II)-catalyzed oxidative cyclization of enamides to 2,5-disubstituted oxazoles via vinylic C-H functionalization |
| Q38974125 | Room temperature, metal-free arylation of aliphatic alcohols |
| Q36499563 | Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor Cells |
| Q52345612 | Ruthenium(II)-enabled para-selective C-H difluoromethylation of anilides and their derivatives. |
| Q28543910 | SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest |
| Q92338239 | Selective C-F Functionalization of Unactivated Trifluoromethylarenes |
| Q41502645 | Selective and Scalable Perfluoroarylation of Nitroalkanes |
| Q47232071 | Selective radical trifluoromethylation of native residues in proteins. |
| Q39312759 | Semisynthetic ursolic acid fluorolactone derivatives inhibit growth with induction of p21(waf1) and induce apoptosis with upregulation of NOXA and downregulation of c-FLIP in cancer cells |
| Q39873974 | Separation of Fluorinated Amino Acids and Oligopeptides from their Non-fluorinated Counterparts using High-performance Liquid Chromatography |
| Q42741143 | Sequential allylic C-H amination/vinylic C-H arylation: a strategy for unnatural amino acid synthesis from α-olefins |
| Q92134474 | Shielding Effect of Micelle for Highly Effective and Selective Monofluorination of Indoles in Water |
| Q39172790 | Silver-mediated trifluoromethoxylation of aryl stannanes and arylboronic acids. |
| Q39547245 | Silver-mediated trifluoromethylation of arenes using TMSCF3. |
| Q91151044 | Stereocontrolled Synthesis of 2-Fluorinated C-Glycosides |
| Q52314785 | Stereoselective cobalt-catalyzed halofluoroalkylation of alkynes. |
| Q37118304 | Stereoselective synthesis of conjugated fluoro enynes |
| Q43086626 | Sterically Demanding Unsymmetrical Diaryl-λ(3)-iodanes for Electrophilic Pentafluorophenylation and an Approach to α-Pentafluorophenyl Carbonyl Compounds with an All-Carbon Stereocenter |
| Q93107245 | Straightforward access to N-trifluoromethyl amides, carbamates, thiocarbamates and ureas |
| Q27664447 | Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity |
| Q89768852 | Structural characterization and Hirshfeld surface analysis of 2-iodo-4-(penta-fluoro-λ6-sulfan-yl)benzo-nitrile |
| Q36624204 | Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists |
| Q39489607 | Structure-activity relationships in tripodal transmembrane anion transporters: the effect of fluorination |
| Q36724814 | Studies toward the oxidative and reductive activation of C-S bonds in 2'-S-aryl-2'-thiouridine derivatives. |
| Q34489910 | Studying regioisomer formation in the Pd-catalyzed fluorination of aryl triflates by deuterium labeling |
| Q39148610 | Substituted 3-benzylcoumarins as allosteric MEK1 inhibitors: design, synthesis and biological evaluation as antiviral agents. |
| Q92927794 | Substrate-Controlled Product Divergence: Silver-Catalyzed Reaction of Trifluoromethyl Ketones with Terminal Alkynes |
| Q41586778 | Syntheses of fluorooxindole and 2-fluoro-2-arylacetic acid derivatives from diethyl 2-fluoromalonate ester |
| Q88663589 | Synthesis and Evaluation of Antiplasmodial Activity of 2,2,2-Trifluoroethoxychalcones and 2-Fluoroethoxy Chalcones against Plasmodium falciparum in Culture |
| Q38740264 | Synthesis and In Vitro Cytotoxic Properties of Polycarbo-Substituted 4-(Arylamino)quinazolines. |
| Q46526956 | Synthesis and In Vitro Cytotoxicity of the 4-(Halogenoanilino)-6-bromoquinazolines and Their 6-(4-Fluorophenyl) Substituted Derivatives as Potential Inhibitors of Epidermal Growth Factor Receptor Tyrosine Kinase |
| Q37664921 | Synthesis and SAR studies of dual AKT/NF-κB inhibitors against melanoma |
| Q34503993 | Synthesis and anticancer activity evaluation of 3,4-mono- and bicyclosubstituted N-(het)aryl trifluoromethyl succinimides |
| Q28595401 | Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs |
| Q47134152 | Synthesis and application of trifluoroethoxy-substituted phthalocyanines and subphthalocyanines |
| Q41896301 | Synthesis and applications of α-trifluoromethylated alkylboron compounds |
| Q42802652 | Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis. |
| Q42237305 | Synthesis and reactivity of aliphatic sulfur pentafluorides from substituted (pentafluorosulfanyl)benzenes. |
| Q47983429 | Synthesis and structure-activity studies on novel analogs of human growth hormone releasing hormone (GHRH) with enhanced inhibitory activities on tumor growth |
| Q92928783 | Synthesis of 3-CF2-Containing Chromones via a Visible-Light-Induced Radical Cascade Reaction of o-Hydroxyaryl Enaminones |
| Q89966313 | Synthesis of 4-(2-fluorophenyl)-7-methoxycoumarin: experimental and computational evidence for intramolecular and intermolecular C-F···H-C bonds |
| Q41972307 | Synthesis of Aryldifluoroamides by Copper-Catalyzed Cross-Coupling |
| Q62032080 | Synthesis of Fluorinated Leishmania Cap Trisaccharides for Diagnostic Tool and Vaccine Development |
| Q59478311 | Synthesis of Fluoroalkyl Pyrazoles from In-Situ-Generated C2F5CHN2and Electron-Deficient Alkenes |
| Q89857941 | Synthesis of Fulvene Vinyl Ethers by Gold Catalysis |
| Q52340414 | Synthesis of Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via a One-Pot (Ugi-3CR/aza Diels-Alder/N-acylation/aromatization/SN2) Process. A Suitable Alternative towards Novel Aza-Analogues of Falipamil. |
| Q42365816 | Synthesis of Trifluoromethoxylated (Hetero)Arenes via OCF3 Migration. |
| Q59353282 | Synthesis of Trifluoromethyl-α,β-unsaturated Lactones and Pyrazolinones and Discovery of Influenza Virus Polymerase Inhibitors |
| Q92860159 | Synthesis of Tris-Heterocycles via a Cascade IMCR/Aza Diels-Alder + CuAAC Strategy |
| Q97543864 | Synthesis of antiviral perfluoroalkyl derivatives of teicoplanin and vancomycin |
| Q89941005 | Synthesis of bicyclo[3.1.0]hexanes by (3 + 2) annulation of cyclopropenes with aminocyclopropanes |
| Q58769313 | Synthesis of chiral α-trifluoromethyl alcohols and ethers via enantioselective Hiyama cross-couplings of bisfunctionalized electrophiles |
| Q92823731 | Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes |
| Q64238170 | Synthesis of enantiopure F-trifluoromethyl cysteine as a structure-mimetic amino acid tracer for glioma imaging |
| Q52728708 | Synthesis of fluoro-functionalized diaryl-λ3-iodonium salts and their cytotoxicity against human lymphoma U937 cells. |
| Q38841376 | Synthesis of new indole-based bisphosphonates and evaluation of their chelating ability in PE/CA-PJ15 cells |
| Q41914414 | Synthesis of trifluoromethylated isoxazolidines: 1,3-dipolar cycloaddition of nitrosoarenes, (trifluoromethyl)diazomethane, and alkenes |
| Q48119060 | Synthesis of α-Chiral Ketones and Chiral Alkanes Using Radical Polar Crossover Reactions of Vinyl Boron Ate Complexes |
| Q47714197 | Synthesis, Cytotoxicity and Molecular Docking Studies of the 9-Substituted 5-Styryltetrazolo[1,5-c]quinazoline Derivatives. |
| Q58697246 | Synthesis, Evaluation for Cytotoxicity and Molecular Docking Studies of Benzo[]furan-Chalcones for Potential to Inhibit Tubulin Polymerization and/or EGFR-Tyrosine Kinase Phosphorylation |
| Q53077899 | Synthesis, Fungicidal Activity and Mode of Action of 4-Phenyl-6-trifluoromethyl-2-aminopyrimidines against Botrytis cinerea. |
| Q90192725 | Synthesis, In Vitro Evaluation and Molecular Docking of the 5-Acetyl-2-aryl-6-hydroxybenzo[b]furans against Multiple Targets Linked to Type 2 Diabetes |
| Q42927838 | Synthesis, Spectral Characterization, In-vitro Antibacterial and Antifungal Activities of Novel (2e)-Ethyl-2-(2-(2, 4-Dinitrophenyl) Hydrazono)-4-(Naphthalen-2-yl)-6-Arylcyclohex-3-Enecarboxylates |
| Q92029231 | Synthesis, X-ray crystal structure, Hirshfeld surface analysis, and molecular docking study of novel inhibitor of hepatitis B: methyl 4-fluoro-3-(morpholinosulfonyl)benzo[b]thiophene-2-carboxylate |
| Q61450167 | Synthesis, biophysical properties, and RNase H activity of 6'-difluoro[4.3.0]bicyclo-DNA |
| Q34053493 | Synthetic and mechanistic aspects of the regioselective base-mediated reaction of perfluoroalkyl- and perfluoroarylsilanes with heterocyclic N-oxides |
| Q28834646 | Synthetic biology approaches to fluorinated polyketides |
| Q92271463 | Systematic Hydrogen-Bond Manipulations To Establish Polysaccharide Structure-Property Correlations |
| Q42291702 | Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor |
| Q87185992 | Targeted fluorination of a nonsteroidal anti-inflammatory drug to prolong metabolic half-life |
| Q58211551 | Targeting Carbonic Anhydrases with Fluorescent BODIPY-Labelled Sulfonamides |
| Q37579319 | Targeting the Endocannabinoid System for Neuroprotection: A (19)F-NMR Study of a Selective FAAH Inhibitor Binding with an Anandamide Carrier Protein, HSA. |
| Q37760799 | The C-F bond as a conformational tool in organic and biological chemistry |
| Q90274970 | The Journey of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) from Lab to Clinic |
| Q50545600 | The Magnesium(II)‐Catalyzed Asymmetric Ketone–Ene Reaction under Solvent‐Free Conditions: Stereocontrolled Access to Enantioenriched Trifluoromethyl‐Substituted Compounds |
| Q41879986 | The difluoromethylene (CF2) group in aliphatic chains: Synthesis and conformational preference of palmitic acids and nonadecane containing CF2 groups |
| Q87431567 | The direct anti-Markovnikov addition of mineral acids to styrenes |
| Q42293575 | The dual role of thiourea in the thiotrifluoromethylation of alkenes. |
| Q35623583 | The palladium-catalyzed trifluoromethylation of vinyl sulfonates |
| Q34105033 | The productive merger of iodonium salts and organocatalysis: a non-photolytic approach to the enantioselective alpha-trifluoromethylation of aldehydes |
| Q84262951 | The role of fluorine atoms in a fluorinated prostaglandin agonist |
| Q46011455 | The role of fluorine in stabilizing the bioactive conformation of dihydroorotate dehydrogenase inhibitors. |
| Q55275345 | The selective electrochemical fluorination of S-alkyl benzothioate and its derivatives. |
| Q36551437 | The toxicity of the N-hydroxy and 6-hydroxy metabolites of 3,4-dichloropropionanilide does not depend on calcium release-activated calcium channel inhibition |
| Q56603992 | The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research |
| Q42383517 | Themed series in organo-fluorine chemistry |
| Q47898057 | Theoretical Study on the Conformational Bioeffect of the Fluorination of Acetylcholine |
| Q49508703 | Theoretical models of inhibitory activity for inhibitors of protein–protein interactions: targeting menin–mixed lineage leukemia with small molecules |
| Q39647534 | Three step synthesis of single diastereoisomers of the vicinal trifluoro motif |
| Q35031035 | Three-component synthesis of C2F5-substituted pyrazoles from C2F5CH2NH2·HCl, NaNO2 and electron-deficient alkynes |
| Q64027903 | Transition-Metal-Free Radical Hydrotrifluoromethylation of Alkynes |
| Q58623742 | Transition-Metal-Free Regioselective C-H Bond Fluorination of 8-Amidoquinolines with Selectfluor |
| Q38244526 | Transitioning organic synthesis from organic solvents to water. What's your E Factor? |
| Q37158035 | Trifluoromethylation of Arylsilanes with [(phen)CuCF3 ] |
| Q52641964 | Trifluoromethylation of Secondary Nitroalkanes. |
| Q34239799 | Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis. |
| Q64024268 | Trifluoromethylthiolation of Unsymmetrical λ3-Iodane Derivatives: Additive-Free, Selective and Scalable Introduction of the SCF3Group |
| Q59071175 | Trifluoromethylthiolation of α-Chloroaldehydes: Access to Quaternary SCF3 -Containing Centers |
| Q33572194 | Trisubstituted 2-trifluoromethyl pyrrolidines via catalytic asymmetric Michael addition/reductive cyclization |
| Q89518882 | Use of α-trifluoromethyl carbanions for palladium-catalysed asymmetric cycloadditions |
| Q41013531 | Vanadium-Catalyzed C(sp(3))-H Fluorination Reactions |
| Q88948863 | Visible Light-Mediated Decarboxylative Alkylation of Pharmaceutically Relevant Heterocycles |
| Q28286045 | Visible light photocatalysis as a greener approach to photochemical synthesis |
| Q34333964 | Visible light photoredox catalysis with transition metal complexes: applications in organic synthesis |
| Q55712381 | Visible light-mediated difluoroalkylation of electron-deficient alkenes. |
| Q42773523 | Visible light-promoted metal-free C-H activation: diarylketone-catalyzed selective benzylic mono- and difluorination |
| Q47375033 | Visible-Light Photocatalytic Decarboxylation of α,β-Unsaturated Carboxylic Acids: Facile Access to Stereoselective Difluoromethylated Styrenes in Batch and Flow |
| Q93002953 | Visible-light Promoted Atom Transfer Radical Addition-Elimination (ATRE) Reaction for the Synthesis of Fluoroalkylated Alkenes Using DMA as Electron-Donor |
| Q42285443 | Visible-light-induced oxidant and metal-free dehydrogenative cascade trifluoromethylation and oxidation of 1,6-enynes with water |
| Q60915719 | eToxPred: a machine learning-based approach to estimate the toxicity of drug candidates |
| Q62784517 | α-Fluorination of carbonyls with nucleophilic fluorine |
| Q48219710 | α-Fluoro-o-cresols: The Key Role of Intramolecular Hydrogen Bonding in Conformational Preference and Hydrogen-Bond Acidity |
| Q47106655 | α-Perfluoroalkyl-β-alkynylation of alkenes via radical alkynyl migration. |
| Q62073093 | β-Lactam Bioconjugates Bearing Luminescent Platinum(II) Tags: Synthesis and Photophysical Characterization |
| Q90025889 | ω-Phthalimidoalkyl Aryl Ureas as Potent and Selective Inhibitors of Cholesterol Esterase |
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