| scholarly article | Q13442814 |
| P356 | DOI | 10.3390/IJMS23010048 |
| P50 | author | Yong-Weon Yi | Q80117200 |
| Seok-Geun Lee | Q55240875 | ||
| Yeon Sun Seong | Q98178756 | ||
| P2093 | author name string | Jeong-Soo Park | |
| Kyu Sic You | |||
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| TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver | Q24304147 | ||
| The phosphatase PHLPP controls the cellular levels of protein kinase C | Q24305122 | ||
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| Tuberous sclerosis‐2 (TSC2) regulates the stability of death‐associated protein kinase‐1 (DAPK) through a lysosome‐dependent degradation pathway | Q24313169 | ||
| Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signaling | Q24314084 | ||
| Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals | Q24314293 | ||
| Nuclear and nucleolar targeting of human ribosomal protein S6 | Q24321240 | ||
| Mdm2 promotes the rapid degradation of p53 | Q24322597 | ||
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| Phosphorylated Ribosomal Protein S6 Is Required for Akt-Driven Hyperplasia and Malignant Transformation, but Not for Hypertrophy, Aneuploidy and Hyperfunction of Pancreatic β-Cells | Q28550394 | ||
| Regulation of protein kinase C ζ by PI 3-kinase and PDK-1 | Q28567633 | ||
| Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites | Q28569134 | ||
| Suprachiasmatic nucleus circadian oscillatory protein, a novel binding partner of K-Ras in the membrane rafts, negatively regulates MAPK pathway | Q28571239 | ||
| c-myc Repression of TSC2 contributes to control of translation initiation and Myc-induced transformation | Q28573044 | ||
| Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis | Q28585415 | ||
| Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6 | Q28588241 | ||
| PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility | Q28590466 | ||
| The p53-mdm-2 autoregulatory feedback loop | Q28609811 | ||
| Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 | ||
| Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B | Q28646131 | ||
| Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway | Q28646919 | ||
| Deferasirox | Q29393588 | ||
| mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt | Q29547767 | ||
| An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1 | Q29614563 | ||
| Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy | Q29615616 | ||
| mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase | Q29616153 | ||
| DRAM, a p53-induced modulator of autophagy, is critical for apoptosis | Q29616308 | ||
| Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity | Q29618117 | ||
| Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells | Q29618245 | ||
| Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α. | Q29871439 | ||
| Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway. | Q30371587 | ||
| A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies | Q30410515 | ||
| Phosphorylation of Eukaryotic Translation Initiation Factor 4B (EIF4B) by Open Reading Frame 45/p90 Ribosomal S6 Kinase (ORF45/RSK) Signaling Axis Facilitates Protein Translation during Kaposi Sarcoma-associated Herpesvirus (KSHV) Lytic Replication | Q30423529 | ||
| Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival | Q30438715 | ||
| Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta | Q30440938 | ||
| A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation | Q30846613 | ||
| Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription | Q31462537 | ||
| Characteristics and clustering of human ribosomal protein genes | Q33234925 | ||
| The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain | Q33277804 | ||
| Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. | Q33390054 | ||
| Hypothalamic Sirt1 regulates food intake in a rodent model system | Q33519539 | ||
| Differentiated vulvar intraepithelial neoplasia contains Tp53 mutations and is genetically linked to vulvar squamous cell carcinoma | Q33522930 | ||
| Pivotal role of mTORC2 and involvement of ribosomal protein S6 in cardioprotective signaling | Q33552565 | ||
| Specialized ribosomes: a new frontier in gene regulation and organismal biology | Q33689623 | ||
| Influence of hyperthermia on the phosphorylation of ribosomal protein S6 from human skin fibroblasts and meningioma cells | Q71037322 | ||
| Heat shock causes diverse changes in the phosphorylation of the ribosomal proteins of mammalian cells | Q71324654 | ||
| The effect of serum, EGF, PGF2 alpha and insulin on S6 phosphorylation and the initiation of protein and DNA synthesis | Q71444130 | ||
| (+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5, 6]cyclohepta[1,2-b]- pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamid e (SCH-66336): a very potent farnesyl protein transferase inhibitor as a novel antitumor agent | Q77580653 | ||
| Clinocopathologic significance of laminin-5 gamma2 chain expression in squamous cell carcinoma of the tongue: immunohistochemical analysis of 67 lesions | Q77839247 | ||
| Mechanism of Cdk2/Cyclin E inhibition by p27 and p27 phosphorylation | Q77960210 | ||
| A 32 kDa protein--whose phosphorylation correlates with oncogenic Ras-induced cell cycle arrest in activated Xenopus egg extracts--is identified as ribosomal protein S6 | Q80502691 | ||
| Notch and PI3K: how is the road traveled? | Q84815124 | ||
| Blockade of Fatty Acid Synthase Induces Ubiquitination and Degradation of Phosphoinositide-3-Kinase Signaling Proteins in Ovarian Cancer | Q85040108 | ||
| Aggregation of Ribosomal Protein S6 at Nucleolus Is Cell Cycle-Controlled and Its Function in Pre-rRNA Processing Is Phosphorylation Dependent | Q86861268 | ||
| Ribosomal protein S6 phosphorylation is associated with epithelial dysplasia and squamous cell carcinoma of the oral cavity | Q87384063 | ||
| Phospholipase D and phosphatidic acid in the biogenesis and cargo loading of extracellular vesicles | Q88938143 | ||
| The functions and regulation of the PTEN tumour suppressor: new modes and prospects | Q88955683 | ||
| NRF2 through RPS6 Activation Is Related to Anti-HER2 Drug Resistance in HER2-Amplified Gastric Cancer | Q90029982 | ||
| Placenta-Specific 8 Is Overexpressed and Regulates Cell Proliferation in Low-Grade Human Pancreatic Neuroendocrine Tumors | Q90275672 | ||
| The mTORC1 signaling modulated by intracellular C3 activation in Paneth cells promotes intestinal epithelial regeneration during acute injury | Q90361982 | ||
| Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells | Q90524541 | ||
| ERK-TSC2 signalling in constitutively-active HRAS mutant HNSCC cells promotes resistance to PI3K inhibition | Q90986199 | ||
| AAVshRNA-mediated PTEN knockdown in adult neurons attenuates activity-dependent immediate early gene induction | Q91210841 | ||
| PARP Inhibitors: Extending Benefit Beyond BRCA-Mutant Cancers | Q91556116 | ||
| Ribosomal Protein S6 promotes stem-like characters in glioma cells | Q91561876 | ||
| The clearance of dead cells by efferocytosis | Q91595744 | ||
| Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia | Q91710497 | ||
| The role of human ribosomal proteins in the maturation of rRNA and ribosome production | Q24322949 | ||
| Phosphorylation and activation of p70s6k by PDK1 | Q24323433 | ||
| The organization of the intron-containing human S6 ribosomal protein (rpS6) gene and determination of its location at chromosome 9p21 | Q24323751 | ||
| AMPK phosphorylation of raptor mediates a metabolic checkpoint | Q24329244 | ||
| AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas | Q24336818 | ||
| IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway | Q24337225 | ||
| PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice | Q24337364 | ||
| 3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling | Q24337691 | ||
| Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex | Q24559347 | ||
| Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing | Q24561760 | ||
| Inhibition of HDM2 and activation of p53 by ribosomal protein L23 | Q24562880 | ||
| Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition | Q24562892 | ||
| Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase | Q24564747 | ||
| Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma | Q24597152 | ||
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Q24599676 | ||
| S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway | Q24603083 | ||
| MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells | Q24603505 | ||
| Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer | Q24617184 | ||
| A molecular mechanism for the effect of lithium on development | Q24629067 | ||
| mTOR: from growth signal integration to cancer, diabetes and ageing | Q24633662 | ||
| High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller | Q24641848 | ||
| Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes | Q24645537 | ||
| Inhibition of S6K1 accounts partially for the anti-inflammatory effects of the arginase inhibitor L-norvaline | Q24647607 | ||
| Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway | Q24648370 | ||
| A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling | Q24678327 | ||
| Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control | Q24679076 | ||
| hDREF regulates cell proliferation and expression of ribosomal protein genes | Q24681438 | ||
| The architecture of mammalian ribosomal protein promoters | Q24802303 | ||
| Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to Function | Q26770762 | ||
| The Pallbearer E3 ligase promotes actin remodeling via RAC in efferocytosis by degrading the ribosomal protein S6 | Q27314962 | ||
| Establishing Rps6 hemizygous mice as a model for studying how ribosomal protein haploinsufficiency impairs erythropoiesis | Q35869411 | ||
| A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway | Q35949097 | ||
| S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells. | Q36095183 | ||
| Cocaine-mediated microglial activation involves the ER stress-autophagy axis. | Q36111649 | ||
| Circumventing Cellular Control of PP2A by Methylation Promotes Transformation in an Akt-Dependent Manner | Q36172723 | ||
| Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer | Q36200159 | ||
| An Asymmetrically Balanced Organization of Kinases versus Phosphatases across Eukaryotes Determines Their Distinct Impacts | Q36263765 | ||
| Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner | Q36277174 | ||
| Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase | Q36278250 | ||
| Isolation and characterization of cloned cDNAs that code for human ribosomal protein S6. | Q36345068 | ||
| Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma | Q36403491 | ||
| eIF3 controls cell size independently of S6K1-activity | Q36414466 | ||
| Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity | Q36421097 | ||
| Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth | Q36429062 | ||
| Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. | Q36470315 | ||
| Stabilization of p21 by mTORC1/4E-BP1 predicts clinical outcome of head and neck cancers. | Q36542415 | ||
| IKK-β mediates hydrogen peroxide induced cell death through p85 S6K1 | Q36560442 | ||
| Butyrate histone deacetylase inhibitors. | Q36574546 | ||
| RB and cell cycle progression | Q36579245 | ||
| Inhibition of constitutively activated phosphoinositide 3-kinase/AKT pathway enhances antitumor activity of chemotherapeutic agents in breast cancer susceptibility gene 1-defective breast cancer cells | Q36652248 | ||
| The ribosomal protein S6 in renal cell carcinoma: functional relevance and potential as biomarker | Q36729436 | ||
| RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation | Q36745240 | ||
| Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma | Q36861785 | ||
| The translational landscape of mTOR signalling steers cancer initiation and metastasis | Q36873513 | ||
| Type I interferons induce autophagy in certain human cancer cell lines | Q36892069 | ||
| A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. | Q36908567 | ||
| Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells | Q36927955 | ||
| Synaptic activation of ribosomal protein S6 phosphorylation occurs locally in activated dendritic domains | Q36935481 | ||
| Cell cycle arrest by glucocorticoids may protect normal tissue and solid tumors from cancer therapy | Q37034910 | ||
| Hematopoietic cell renewal systems: mechanisms of coping and failing after chronic exposure to ionizing radiation | Q37035046 | ||
| Elevated phospho-S6 expression is associated with metastasis in adenocarcinoma of the lung | Q37038176 | ||
| CDK inhibitors: cell cycle regulators and beyond | Q37081857 | ||
| Overexpression of Notch3 and pS6 Is Associated with Poor Prognosis in Human Ovarian Epithelial Cancer. | Q37092956 | ||
| Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin | Q37110578 | ||
| Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). | Q39668305 | ||
| Different cytoplasmic/nuclear distribution of S6 protein phosphorylated at S240/244 and S235/236. | Q39681063 | ||
| A functional link between polo-like kinase 1 and the mammalian target-of-rapamycin pathway? | Q39712992 | ||
| PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR. | Q39728074 | ||
| Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy | Q39739155 | ||
| Expression of laminin gamma2 chain monomer enhances invasive growth of human carcinoma cells in vivo | Q39741866 | ||
| Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors. | Q39779613 | ||
| Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin | Q39827828 | ||
| Inhibitor hijacking of Akt activation | Q39847621 | ||
| Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic beta-cells | Q39859443 | ||
| The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1. | Q39870984 | ||
| Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein-protein interactions for substrate recognition | Q39875318 | ||
| PD-1 Checkpoint Blockade in Combination with an mTOR Inhibitor Restrains Hepatocellular Carcinoma Growth Induced by Hepatoma Cell-Intrinsic PD-1. | Q40124899 | ||
| Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mimics Epstein-Barr virus EBNA1 immune evasion through central repeat domain effects on protein processing | Q40128647 | ||
| Gain and overexpression of the oncostatin M receptor occur frequently in cervical squamous cell carcinoma and are associated with adverse clinical outcome | Q40129856 | ||
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| Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins | Q40248475 | ||
| Structural bioinformatics-based design of selective, irreversible kinase inhibitors | Q40307105 | ||
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| The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity | Q40399733 | ||
| Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells | Q40435523 | ||
| Fbxo28 promotes mitotic progression and regulates topoisomerase IIα-dependent DNA decatenation. | Q40535183 | ||
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| A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets. | Q40643741 | ||
| Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency | Q40890351 | ||
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| Arginase modulates nitric oxide production in activated macrophages | Q41066421 | ||
| Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes | Q41271748 | ||
| Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer | Q41392040 | ||
| Integrated expression profiles analysis reveals novel predictive biomarker in pancreatic ductal adenocarcinoma | Q41592795 | ||
| LKB1 regulates pancreatic beta cell size, polarity, and function | Q41870049 | ||
| ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding | Q41953170 | ||
| Functional characterization of transcriptional regulatory elements in the upstream region and intron 1 of the human S6 ribosomal protein gene | Q41989466 | ||
| Androgen-sensitive microsomal signaling networks coupled to the proliferation and differentiation of human prostate cancer cells | Q42200676 | ||
| p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes. | Q42277847 | ||
| Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies. | Q42412981 | ||
| Phosphorylated S6 as an immunohistochemical biomarker of vulvar intraepithelial neoplasia | Q42439942 | ||
| Identification of highly specific localized sequence motifs in human ribosomal protein gene promoters | Q42487783 | ||
| Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients | Q42500588 | ||
| Chemical modification of rapamycin: the discovery of SDZ RAD | Q42540012 | ||
| Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season. | Q42774255 | ||
| p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1). | Q42796101 | ||
| Synthetic lethality screens reveal RPS6 and MST1R as modifiers of insulin-like growth factor-1 receptor inhibitor activity in childhood sarcomas | Q42854019 | ||
| Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals | Q43127521 | ||
| Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein | Q43136831 | ||
| AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity | Q43211411 | ||
| ITD- and FL-induced FLT3 signal transduction leads to increased C/EBPbeta-LIP expression and LIP/LAP ratio by different signalling modules | Q43230779 | ||
| Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway | Q43250891 | ||
| Mammalian target of rapamycin signaling activation patterns in pancreatic neuroendocrine tumors | Q43965111 | ||
| Apoptosis induced by PGC-1β in breast cancer cells is mediated by the mTOR pathway | Q44379265 | ||
| Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex | Q44606826 | ||
| MicroRNA-451 regulates AMPK/mTORC1 signaling and fascin1 expression in HT-29 colorectal cancer | Q45056952 | ||
| Cooperation between fibroblast growth factor receptor-4 and ErbB2 in regulation of cyclin D1 translation | Q45065669 | ||
| Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent | Q33716155 | ||
| Akt-dependent cell size regulation by the adhesion molecule on glia occurs independently of phosphatidylinositol 3-kinase and Rheb signaling. | Q33724411 | ||
| ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS | Q33733064 | ||
| Ribosomopathies: human disorders of ribosome dysfunction | Q33806050 | ||
| Characterization of the human LPIN1-encoded phosphatidate phosphatase isoforms | Q33825194 | ||
| Growth controls connect: interactions between c-myc and the tuberous sclerosis complex-mTOR pathway | Q33831975 | ||
| FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1. | Q33855172 | ||
| PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2. | Q33860504 | ||
| Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase | Q33890035 | ||
| Intracellular parasitism with Toxoplasma gondii stimulates mammalian-target-of-rapamycin-dependent host cell growth despite impaired signalling to S6K1 and 4E-BP1. | Q33894468 | ||
| Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers | Q33917649 | ||
| Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression | Q33957174 | ||
| Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E | Q33980041 | ||
| Autophagy impairment induces premature senescence in primary human fibroblasts. | Q33999533 | ||
| Activation of Sirt1 by Resveratrol Inhibits TNF-α Induced Inflammation in Fibroblasts | Q34070565 | ||
| Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway | Q34132255 | ||
| CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy | Q34155045 | ||
| Discovery of OSI-906: a selective and orally efficacious dual inhibitor of the IGF-1 receptor and insulin receptor | Q34172489 | ||
| La Autoantigen Mediates Oxidant Induced De Novo Nrf2 Protein Translation | Q34243606 | ||
| Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation | Q34286691 | ||
| Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation. | Q34417585 | ||
| The role of eIF3 and its individual subunits in cancer | Q34450907 | ||
| 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro | Q34452063 | ||
| VHL, the story of a tumour suppressor gene | Q34455226 | ||
| Ribosomal proteins: functions beyond the ribosome | Q34465473 | ||
| Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance | Q34466060 | ||
| A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells | Q34518858 | ||
| Small ribosomal subunits associate with nuclear myosin and actin in transit to the nuclear pores. | Q34552520 | ||
| BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. | Q34575151 | ||
| Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition | Q34577381 | ||
| Regulation of Ribosomal Protein S6 Phosphorylation by Casein Kinase 1 and Protein Phosphatase 1 | Q34624565 | ||
| Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) | Q34675192 | ||
| mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells | Q34675637 | ||
| MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products | Q34756212 | ||
| Protein kinase CK2: a challenge to canons | Q34875408 | ||
| Protein kinase CK2: structure, regulation and role in cellular decisions of life and death | Q34978734 | ||
| Neutral Sphingomyelinase-2 Mediates Growth Arrest by Retinoic Acid through Modulation of Ribosomal S6 Kinase | Q35065231 | ||
| Relieving Autophagy and 4EBP1 from Rapamycin Resistance | Q35096637 | ||
| Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. | Q35116967 | ||
| Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia | Q35125923 | ||
| Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling. | Q35162237 | ||
| Ribosomal Protein S6 Interacts with the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus | Q35192690 | ||
| Phosphorylation of Raptor by p38β Participates in Arsenite-induced Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation | Q35213239 | ||
| Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1 | Q35224421 | ||
| Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family | Q35234179 | ||
| Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome | Q35266227 | ||
| Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32 | Q35356825 | ||
| Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesis | Q35500554 | ||
| Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation | Q35571394 | ||
| Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5' terminal oligopyrimidine tract | Q35582995 | ||
| PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer | Q35610581 | ||
| Trastuzumab regimens for HER2-overexpressing metastatic breast cancer | Q35625375 | ||
| Dual inhibition of EGFR and MET induces synthetic lethality in triple-negative breast cancer cells through downregulation of ribosomal protein S6 | Q35625440 | ||
| Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias | Q35642790 | ||
| Inhibition of p70S6K1 Activation by Pdcd4 Overcomes the Resistance to an IGF-1R/IR Inhibitor in Colon Carcinoma Cells | Q35685322 | ||
| Pleiotropic mechanisms facilitated by resveratrol and its metabolites. | Q35692517 | ||
| BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536 | Q35697342 | ||
| Challenges in the development of anti-epidermal growth factor receptor therapies in breast cancer | Q35723772 | ||
| Allelic loss in human papillomavirus-positive and -negative vulvar squamous cell carcinomas | Q35786864 | ||
| Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment | Q35793782 | ||
| Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins | Q35830128 | ||
| Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy | Q35836566 | ||
| Resveratrol Attenuates Doxorubicin-Induced Cardiomyocyte Death via Inhibition of p70 S6 Kinase 1-Mediated Autophagy | Q35847671 | ||
| Cyclin-dependent Kinase 5 (Cdk5)-dependent Phosphorylation of p70 Ribosomal S6 Kinase 1 (S6K) Is Required for Dendritic Spine Morphogenesis. | Q35860823 | ||
| Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo | Q28368373 | ||
| HER2 confers drug resistance of human breast cancer cells through activation of NRF2 by direct interaction | Q28383407 | ||
| The N-terminal region of p27 inhibits HIF-1α protein translation in ribosomal protein S6-dependent manner by regulating PHLPP-Ras-ERK-p90RSK axis | Q28383901 | ||
| Comparative analysis of NRF2-responsive gene expression in AcPC-1 pancreatic cancer cell line | Q28384407 | ||
| Regulation of Nrf2—an update | Q28388589 | ||
| The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism | Q28392347 | ||
| Inhibition of NRF2 by PIK-75 augments sensitivity of pancreatic cancer cells to gemcitabine | Q28396251 | ||
| Mice deficient in ribosomal protein S6 phosphorylation suffer from muscle weakness that reflects a growth defect and energy deficit | Q28475539 | ||
| S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer | Q28477972 | ||
| Attenuation of 40S Ribosomal Subunit Abundance Differentially Affects Host and HCV Translation and Suppresses HCV Replication | Q28481243 | ||
| p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 | Q28505037 | ||
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
| Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway | Q28510620 | ||
| Ribosomal protein S6 gene haploinsufficiency is associated with activation of a p53-dependent checkpoint during gastrulation | Q28513144 | ||
| Phosphorylation of ribosomal proteins in HeLa cells infected with vaccinia virus | Q45882276 | ||
| mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor | Q46119164 | ||
| Synaptically driven phosphorylation of ribosomal protein S6 is differentially regulated at active synapses versus dendrites and cell bodies by MAPK and PI3K/mTOR signaling pathways. | Q46703393 | ||
| The role of diacylglyceride generation by phospholipase D and phosphatidic acid phosphatase in the activation of 5-lipoxygenase in polymorphonuclear leukocytes | Q46792406 | ||
| Phospho-S6 ribosomal protein: a potential new predictive sarcoma marker for targeted mTOR therapy | Q46834814 | ||
| Casein kinase I transduces Wnt signals | Q47069139 | ||
| Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling. | Q47144046 | ||
| Phosphorylated ribosomal protein S6 correlation with p21 expression and inverse association with tumor size in oral squamous cell carcinoma | Q47202432 | ||
| Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice | Q47222234 | ||
| Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease | Q47252033 | ||
| The mammalian ULK1 complex and autophagy initiation. | Q47301180 | ||
| Discrepancy Between Low Levels of mTOR Activity and High Levels of P-S6 in Primary Central Nervous System Lymphoma May Be Explained by PAS Domain-Containing Serine/Threonine-Protein Kinase-Mediated Phosphorylation. | Q47844692 | ||
| Effects of metformin on colorectal cancer stem cells depend on alterations in glutamine metabolism | Q47870743 | ||
| Structural characterization of the mouse ribosomal protein S6-encoding gene | Q48059076 | ||
| Aldo-Keto Reductase Regulation by the Nrf2 System: Implications for Stress Response, Chemotherapy Drug Resistance, and Carcinogenesis | Q48251191 | ||
| PKA-dependent phosphorylation of ribosomal protein S6 does not correlate with translation efficiency in striatonigral and striatopallidal medium-sized spiny neurons | Q48284853 | ||
| Targeting Glutamine Metabolism for Cancer Treatment | Q49632469 | ||
| Knockdown of human serine/threonine kinase 33 suppresses human small cell lung carcinoma by blocking RPS6/BAD signaling transduction | Q50141792 | ||
| Activation of mTOR/S6K But Not MAPK Pathways Might Be Associated With High Ki-67, ER(+), and HER2(-) Breast Cancer | Q51016749 | ||
| mTORC1 and SIRT1 Cooperate to Foster Expansion of Gut Adult Stem Cells during Calorie Restriction | Q51680938 | ||
| Downregulation of ribosomal protein S6 inhibits the growth of non-small cell lung cancer by inducing cell cycle arrest, rather than apoptosis | Q51698975 | ||
| Receptor for activated C kinase 1 (RACK1) promotes the progression of OSCC via the AKT/mTOR pathway | Q51712592 | ||
| MiR-129-5p Sensitizes the Response of Her-2 Positive Breast Cancer to Trastuzumab by Reducing Rps6. | Q51752278 | ||
| Requirement for a Drosophila E3-ubiquitin ligase in phagocytosis of apoptotic cells | Q51975130 | ||
| ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses. | Q52087842 | ||
| Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial. | Q53158182 | ||
| Reciprocal expression of p-AMPKa and p-S6 is strongly associated with the prognosis of gastric cancer | Q53293550 | ||
| Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma | Q53576256 | ||
| Identification of nucleosome assembly protein 1 (NAP1) as an interacting partner of plant ribosomal protein S6 (RPS6) and a positive regulator of rDNA transcription | Q53593265 | ||
| Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma. | Q54108752 | ||
| Signaling pathways involved in the regulation of mRNA translation. | Q54118148 | ||
| Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer | Q54273913 | ||
| Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1. | Q54521077 | ||
| Early changes in rpS6 phosphorylation and BH3 profiling predict response to chemotherapy in AML cells. | Q54979826 | ||
| JMJD5 is a human arginyl C-3 hydroxylase. | Q55077889 | ||
| Inhibition of protein phosphatases-1 and -2A with acanthifolicin | Q57310222 | ||
| p27 inhibits CDK6/CCND1 complex formation resulting in cell cycle arrest and inhibition of cell proliferation | Q57461755 | ||
| FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells | Q57788900 | ||
| Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice | Q61776577 | ||
| AZD1208, a Pan-Pim Kinase Inhibitor, Has Anti-Growth Effect on 93T449 Human Liposarcoma Cells via Control of the Expression and Phosphorylation of Pim-3, mTOR, 4EBP-1, S6, STAT-3 and AMPK | Q61815153 | ||
| DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway | Q64060122 | ||
| Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection | Q64074466 | ||
| Inhibition of mTOR complex 1/p70 S6 kinase signaling elevates PD-L1 levels in human cancer cells through enhancing protein stabilization accompanied with enhanced β-TrCP degradation | Q91968800 | ||
| Relationship between Ribosomal Protein S6-pS240 Expression and other Prognostic Factors in Non-Special Type Invasive Breast Cancer | Q91970333 | ||
| Wild-type p53-induced phosphatase 1 promotes vascular smooth muscle cell proliferation and neointima hyperplasia after vascular injury via p-adenosine 5'-monophosphate-activated protein kinase/mammalian target of rapamycin complex 1 pathway | Q92342262 | ||
| Regulation of Ribosomal Proteins on Viral Infection | Q92350688 | ||
| Hallmarks of senescence and aging | Q92402360 | ||
| microRNA 92b-3p regulates primordial follicle assembly by targeting TSC1 in neonatal mouse ovaries | Q92423737 | ||
| Identification of a novel S6K1 inhibitor, rosmarinic acid methyl ester, for treating cisplatin-resistant cervical cancer | Q92457405 | ||
| Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells | Q92472117 | ||
| Von Hippel-Lindau tumor suppressor (VHL) stimulates TOR signaling by interacting with phosphoinositide 3-kinase (PI3K) | Q92781390 | ||
| BTF3 Silencing Inhibits the Proliferation of Osteosarcoma Cells | Q92795347 | ||
| MicroRNA-99b suppresses human cervical cancer cell activity by inhibiting the PI3K/AKT/mTOR signaling pathway | Q93336878 | ||
| Mesenchymal Stem/Stromal Cell-Derived Exosomes for Immunomodulatory Therapeutics and Skin Regeneration | Q94557298 | ||
| Selumetinib: First Approval | Q96173379 | ||
| IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas | Q98725861 | ||
| Knockdown of ribosomal protein S6 suppresses proliferation, migration, and invasion in epithelial ovarian cancer | Q99628470 | ||
| Recent advancements in PARP inhibitors-based targeted cancer therapy | Q100301727 | ||
| S6 ribosomal protein phosphorylation is associated with malignancy of intraductal papillary mucinous neoplasm of the pancreas | Q100417707 | ||
| Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma | Q100750083 | ||
| Cancer-Associated Angiogenesis: The Endothelial Cell as a Checkpoint for Immunological Patrolling | Q102139199 | ||
| The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy | Q104111657 | ||
| New Actors Driving the Epithelial-Mesenchymal Transition in Cancer: The Role of Leptin | Q104493752 | ||
| The distribution of cellular turnover in the human body | Q104873201 | ||
| The effect of three-dimensional cultured adipose tissue-derived mesenchymal stem cell–conditioned medium and the antiaging effect of cosmetic products containing the medium | Q126441836 | ||
| p62 is a key regulator of nutrient sensing in the mTORC1 pathway. | Q38666713 | ||
| Cross-talks via mTORC2 can explain enhanced activation in response to insulin in diabetic patients. | Q38725775 | ||
| Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice | Q38738135 | ||
| mTORC1-Dependent Metabolic Reprogramming Underlies Escape from Glycolysis Addiction in Cancer Cells | Q38780140 | ||
| PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways | Q38811661 | ||
| Rapamycin modulation of p70 S6 kinase signaling inhibits Rift Valley fever virus pathogenesis | Q38820203 | ||
| Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy | Q38826484 | ||
| Phosphorylated ribosomal S6 (p-rpS6) as a post-treatment indicator of HER2 signalling targeted drug resistance | Q38838851 | ||
| The role of ribosomal proteins in the regulation of cell proliferation, tumorigenesis, and genomic integrity | Q38854116 | ||
| Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase. | Q38916532 | ||
| Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway | Q38923281 | ||
| Combinatorial action of transcription factors orchestrates cell cycle-dependent expression of the ribosomal protein genes and ribosome biogenesis | Q39013977 | ||
| TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3. | Q39014212 | ||
| Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer | Q39024340 | ||
| Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers | Q39029421 | ||
| Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction. | Q39037345 | ||
| Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells | Q39092155 | ||
| Inhibition of p70S6K does not mimic the enhancement of Akt phosphorylation by rapamycin | Q39151022 | ||
| Phosphorylation of nuclear and cytoplasmic pools of ribosomal protein S6 during cell cycle progression | Q39223292 | ||
| Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. | Q39240902 | ||
| BMS-754807, a Small-Molecule Inhibitor of Insulin-like Growth Factor-1 Receptor/Insulin Receptor, Enhances Gemcitabine Response in Pancreatic Cancer | Q39263339 | ||
| Prognostic significance and function of phosphorylated ribosomal protein S6 in esophageal squamous cell carcinoma. | Q39274647 | ||
| Combinations of BRAF, MEK, and PI3K/mTOR Inhibitors Overcome Acquired Resistance to the BRAF Inhibitor GSK2118436 Dabrafenib, Mediated byNRASorMEKMutations | Q39385617 | ||
| 5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer. | Q39424739 | ||
| Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition | Q39428029 | ||
| Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts. | Q39441263 | ||
| Small Molecules, Inhibitors of DNA-PK, Targeting DNA Repair, and Beyond | Q39471754 | ||
| Isoform-selective inhibition of phosphoinositide 3-kinase: identification of a new region of nonconserved amino acids critical for p110α inhibition | Q39502963 | ||
| Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer | Q39507521 | ||
| Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1 | Q39528760 | ||
| Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR | Q39538410 | ||
| Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis. | Q39592731 | ||
| PI(3) kinase is associated with a mechanism of immunoresistance in breast and prostate cancer | Q37206391 | ||
| Physiological roles of ribosomal protein S6: one of its kind | Q37243586 | ||
| Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR) | Q37257487 | ||
| Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941 | Q37281824 | ||
| Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of EGFR kinase inhibitors in triple-negative breast cancer cells. | Q37294562 | ||
| A novel Hap1-Tsc1 interaction regulates neuronal mTORC1 signaling and morphogenesis in the brain. | Q37309501 | ||
| Aging: ROS or TOR. | Q37312907 | ||
| Targeting of glioblastoma cell lines and glioma stem cells by combined PIM kinase and PI3K-p110α inhibition | Q37362875 | ||
| The latency-associated nuclear antigen, a multifunctional protein central to Kaposi's sarcoma-associated herpesvirus latency | Q37380228 | ||
| Optimal targeting of the mTORC1 kinase in human cancer | Q37398288 | ||
| TORC1 Suppression Predicts Responsiveness to RAF and MEK Inhibition in BRAF- Mutant Melanoma | Q37401151 | ||
| How common are extraribosomal functions of ribosomal proteins? | Q37442012 | ||
| S6K in geroconversion | Q37452951 | ||
| Identification and characterization of a mitogen-activated S6 kinase | Q37482357 | ||
| Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells | Q37544392 | ||
| AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia | Q37564783 | ||
| Addiction to protein kinase CK2: a common denominator of diverse cancer cells? | Q37576535 | ||
| p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage | Q37583480 | ||
| mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer | Q37605004 | ||
| Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling | Q37699205 | ||
| The regulation of protein synthesis in cancer | Q37726457 | ||
| Regulation and function of the RSK family of protein kinases | Q37970380 | ||
| The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation | Q38065567 | ||
| The p90 RSK family members: common functions and isoform specificity | Q38130898 | ||
| mTORC1 status dictates tumor response to targeted therapeutics. | Q38142727 | ||
| 2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy | Q38248897 | ||
| Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation | Q38266874 | ||
| Translational control by oncogenic signaling pathways. | Q38283476 | ||
| Inhibition of interleukin-1-stimulated NF-kappaB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity | Q38320915 | ||
| Unmasking a growth factor/oncogene-activated S6 phosphorylation cascade | Q38331550 | ||
| Lipin1 is a key factor for the maturation and maintenance of adipocytes in the regulatory network with CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma 2. | Q38359945 | ||
| MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo | Q38431323 | ||
| Alpha linolenic acid and oleic acid additively down-regulate malignant potential and positively cross-regulate AMPK/S6 axis in OE19 and OE33 esophageal cancer cells | Q38435121 | ||
| Ribosomal Protein S6 Phosphorylation: Four Decades of Research | Q38651385 | ||
| Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418 | Q27641873 | ||
| PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains | Q27649928 | ||
| Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases | Q27652488 | ||
| Structural basis for translational inhibition by the tumour suppressor Pdcd4 | Q27653464 | ||
| Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer | Q27672081 | ||
| Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin | Q27684091 | ||
| Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation | Q27684731 | ||
| Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling | Q27851628 | ||
| Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway. | Q27851698 | ||
| TSC2 mediates cellular energy response to control cell growth and survival | Q27860970 | ||
| 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. | Q27863657 | ||
| Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins | Q28085364 | ||
| A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation | Q28119143 | ||
| The hallmarks of aging | Q28131641 | ||
| Characterization of S6K2, a novel kinase homologous to S6K1 | Q28144592 | ||
| Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt | Q28144601 | ||
| Regulation of HDM2 activity by the ribosomal protein L11 | Q28184745 | ||
| Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan | Q28203572 | ||
| Phosphatidic Acid-Mediated Mitogenic Activation of mTOR Signaling | Q28208274 | ||
| DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1 | Q28215916 | ||
| PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth | Q28243336 | ||
| Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis | Q28246808 | ||
| Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils | Q28249042 | ||
| Characterization of Molecularly Cloned Human 5-Aminoimidazole-4-Carboxamide Ribonucleotide Transformylase | Q28255217 | ||
| Effect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activity | Q28255760 | ||
| Lipopolysaccharide-induced cyclooxygenase-2 expression in human U937 macrophages is phosphatidic acid phosphohydrolase-1-dependent | Q28261638 | ||
| Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent | Q28262376 | ||
| S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth | Q28269583 | ||
| Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5 | Q28276949 | ||
| mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events | Q28281590 | ||
| RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs | Q28286431 | ||
| Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation | Q28291584 | ||
| Characterization of potentialS-nitrosylation sites in the myocardium | Q28304250 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 48 | |
| P577 | publication date | 2021-12-21 | |
| P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
| P1476 | title | Ribosomal Protein S6: A Potential Therapeutic Target against Cancer? | |
| P478 | volume | 23 |
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