Reconstruction and functional characterization of the human mitochondrial metabolic network based on proteomic and biochemical data

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Reconstruction and functional characterization of the human mitochondrial metabolic network based on proteomic and biochemical data is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M403782200
P698PubMed publication ID15205464
P5875ResearchGate publication ID8503404

P50authorBernhard PalssonQ4894212
P2093author name stringThuy D Vo
Harvey J Greenberg
P2860cites workA MILP-based flux alternative generation and NMR experimental design strategy for metabolic engineering.Q43566747
Characterizing the metabolic phenotype: A phenotype phase plane analysisQ43824264
The genome-scale metabolic extreme pathway structure in Haemophilus influenzae shows significant network redundancy.Q44019204
Analytical solutions for (13)C isotopomer analysis of complex metabolic conditions: substrate oxidation, multiple pyruvate cycles, and gluconeogenesisQ44735605
Mitochondrial pyruvate transport in working guinea-pig heart. Work-related vs. carrier-mediated control of pyruvate oxidationQ46161489
The challenges of in silico biologyQ46255466
The lipid composition of mitochondrial and microsomal fractions of human myocardial homogenatesQ53981740
Proteomic analysis of cancer-cell mitochondriaQ54687587
Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondriaQ24291715
Characterization of the human heart mitochondrial proteomeQ24294999
Extreme pathway lengths and reaction participation in genome-scale metabolic networksQ24682088
Sequence and organization of the human mitochondrial genomeQ27860659
The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoformsQ28114905
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranesQ28509935
BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosisQ28594183
Relative contributions of heart mitochondria glutathione peroxidase and catalase to H(2)O(2) detoxification in in vivo conditionsQ28610679
Evidence that phosphatidylserine is imported into mitochondria via a mitochondria-associated membrane and that the majority of mitochondrial phosphatidylethanolamine is derived from decarboxylation of phosphatidylserineQ28647537
Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier familyQ29011734
The effects of alternate optimal solutions in constraint-based genome-scale metabolic modelsQ29616019
A genetic approach to identifying mitochondrial proteinsQ31130979
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamicsQ33947602
Advances in flux balance analysisQ33973453
Characterization of the unidirectional transport of carnitine catalyzed by the reconstituted carnitine carrier from rat liver mitochondriaQ34016721
The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiaeQ34160757
Metabolic modeling of microbial strains in silico.Q34179356
The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age.Q34497897
Metabolic integration during the evolutionary origin of mitochondriaQ35219213
Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic modelQ35574107
Determination of redundancy and systems properties of the metabolic network of Helicobacter pylori using genome-scale extreme pathway analysis.Q35784412
Fatty acid composition of human heart phospholipids: data from 53 biopsy specimensQ36498984
Lipids of mitochondriaQ38148540
Flux coupling analysis of genome-scale metabolic network reconstructions.Q40497938
Theory for the systemic definition of metabolic pathways and their use in interpreting metabolic function from a pathway-oriented perspectiveQ41724911
Theoretical studies on the control of oxidative phosphorylation in muscle mitochondria: application to mitochondrial deficienciesQ41791437
Diabetes and mitochondrial oxidative stress: a study using heart mitochondria from the diabetic Goto-Kakizaki rat.Q42165041
Phospholipid content and fatty acid composition of human heartQ42643261
Extreme pathways and Kirchhoff's second law.Q43122158
P433issue38
P407language of work or nameEnglishQ1860
P921main subjectmetabolic networkQ2263094
P304page(s)39532-39540
P577publication date2004-06-17
P1433published inJournal of Biological ChemistryQ867727
P1476titleReconstruction and functional characterization of the human mitochondrial metabolic network based on proteomic and biochemical data
P478volume279

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cites work (P2860)
Q55402486A Constraint-Based Model Analysis of Enterocyte Mitochondrial Adaptation to Dietary Interventions of Lipid Type and Lipid Load.
Q62721791A Model Integration Pipeline for the Improvement of Human Genome-Scale Metabolic Reconstructions
Q33945843A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle
Q53327243A method for accounting for maintenance costs in flux balance analysis improves the prediction of plant cell metabolic phenotypes under stress conditions.
Q36277163A multi-objective constraint-based approach for modeling genome-scale microbial ecosystems
Q34063123A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology
Q34906417A panoramic overview of mitochondria and mitochondrial redox biology
Q29031028Applications of genome-scale metabolic reconstructions
Q34361776Assessment of Metabolic Phenotypes in Patients with Non-ischemic Dilated Cardiomyopathy Undergoing Cardiac Resynchronization Therapy
Q39776363Bayesian flux balance analysis applied to a skeletal muscle metabolic model.
Q30989837Biological networks and analysis of experimental data in drug discovery
Q33252676Building the power house: recent advances in mitochondrial studies through proteomics and systems biology
Q34396816CardioNet: a human metabolic network suited for the study of cardiomyocyte metabolism
Q21092879Computational prediction of human metabolic pathways from the complete human genome
Q41846171Computational reconstruction of tissue‐specific metabolic models: application to human liver metabolism
Q33422147Connecting extracellular metabolomic measurements to intracellular flux states in yeast
Q26767203Constraint Based Modeling Going Multicellular
Q94103027Current Awareness on Comparative and Functional Genomics
Q42706144Deep epistasis in human metabolism
Q33300475Estimation of the number of extreme pathways for metabolic networks
Q37930590Eukaryotic metabolism: measuring compartment fluxes
Q36217271Expanded metabolic reconstruction of Helicobacter pylori (iIT341 GSM/GPR): an in silico genome-scale characterization of single- and double-deletion mutants
Q45139897Exploring mitochondrial evolution and metabolism organization principles by comparative analysis of metabolic networks
Q42801045Flexibility in energy metabolism supports hypoxia tolerance in Drosophila flight muscle: metabolomic and computational systems analysis
Q43740877Flux balance analysis of biological systems: applications and challenges.
Q46639912Flux balance analysis of genome-scale metabolic model of rice (Oryza sativa): aiming to increase biomass
Q37442434Gene expression profiling and the use of genome-scale in silico models of Escherichia coli for analysis: providing context for content
Q29616789Genome-scale models of microbial cells: evaluating the consequences of constraints
Q24794109Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N315: an initial draft to the two-dimensional annotation
Q28469016Identification of genome-scale metabolic network models using experimentally measured flux profiles
Q37413833Identification of mitochondrial disease genes through integrative analysis of multiple datasets
Q33970067Imaging and modeling of myocardial metabolism
Q34137584In silico models of cancer
Q41764897Large-scale identification of genetic design strategies using local search
Q38056722Mechanistic modeling of aberrant energy metabolism in human disease
Q43704553MetDFBA: incorporating time-resolved metabolomics measurements into dynamic flux balance analysis
Q33849784Metabolic Network-Based Interpretation of Gene Expression Data Elucidates Human Cellular Metabolism
Q37601038Metabolic systems biology
Q33235593Metabolite coupling in genome-scale metabolic networks
Q38084628Mitochondrial energetic metabolism—some general principles
Q59797049Mitoproteomics: Tackling Mitochondrial Dysfunction in Human Disease
Q38575301Modeling strategies to study metabolic pathways in progression to type 1 diabetes--Challenges and opportunities
Q28484385MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models
Q28752359Multiscale modeling of cardiac cellular energetics
Q81798711Network-based prediction of human tissue-specific metabolism
Q38102990Novel insights into obesity and diabetes through genome-scale metabolic modeling
Q42101147Optimal flux spaces of genome-scale stoichiometric models are determined by a few subnetworks
Q37040312Photosynthetic metabolism of C3 plants shows highly cooperative regulation under changing environments: a systems biological analysis
Q34205663Quantitative Analysis of Cellular Metabolic Dissipative, Self-Organized Structures
Q35040014Reconstruction and analysis of human kidney-specific metabolic network based on omics data
Q33417923Reconstruction of metabolic pathways for the cattle genome
Q41358808Reconstruction of pathways associated with amino acid metabolism in human mitochondria
Q33236279SNA--a toolbox for the stoichiometric analysis of metabolic networks
Q41828147Soft constraints-based multiobjective framework for flux balance analysis
Q83152782Stoichiometric network reconstruction and analysis of yeast sphingolipid metabolism incorporating different states of hydroxylation
Q34481468Systematic analysis of conservation relations in Escherichia coli genome-scale metabolic network reveals novel growth media
Q37030590Systematic screens for human disease genes, from yeast to human and back
Q61803767Systems Biology Approaches Toward Understanding Primary Mitochondrial Diseases
Q35162461Systems approaches to molecular cancer diagnostics.
Q36212769Systems-ADME/Tox: resources and network approaches
Q39084331Targeting endothelial metabolism for anti-angiogenesis therapy: A pharmacological perspective
Q35427460The Mitochondrial Proteome and Human Disease
Q37696969Towards genome-scale signalling network reconstructions
Q36371202Towards multidimensional genome annotation
Q39076595Traditional and novel tools to probe the mitochondrial metabolism in health and disease
Q26752519Transcriptomics resources of human tissues and organs
Q26863127Using extracellular matrix proteomics to understand left ventricular remodeling
Q33437242Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes
Q35624874Using the reconstructed genome‐scale human metabolic network to study physiology and pathology
Q33958875iAB-RBC-283: A proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states

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