Positive regulation by small RNAs and the role of Hfq

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Positive regulation by small RNAs and the role of Hfq is …
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scholarly articleQ13442814

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P819ADS bibcode2010PNAS..107.9602S
P356DOI10.1073/PNAS.1004435107
P932PMC publication ID2906882
P698PubMed publication ID20457943
P5875ResearchGate publication ID44587780

P50authorSusan GottesmanQ19642513
Sarah A WoodsonQ42220722
Pierre MandinQ58327583
P2093author name stringNadim Majdalani
Toby Soper
P2860cites workThe RNA-binding protein HF-I, known as a host factor for phage Qbeta RNA replication, is essential for rpoS translation in Escherichia coliQ34383062
Controlling mRNA stability and translation with small, noncoding RNAsQ35737955
A rapid and convenient method for the preparation and storage of competent bacterial cellsQ36001361
Effect of salt and RNA structure on annealing and strand displacement by Hfq.Q37393528
Coincident Hfq binding and RNase E cleavage sites on mRNA and small regulatory RNAsQ39784092
Mutations that increase expression of the rpoS gene and decrease its dependence on hfq function in Salmonella typhimuriumQ39844182
Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, HfqQ21145046
Mfold web server for nucleic acid folding and hybridization predictionQ24498105
Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like proteinQ24536928
Identification of the Hfq-binding site on DsrA RNA: Hfq binds without altering DsrA secondary structureQ24540168
Hfq is necessary for regulation by the untranslated RNA DsrAQ24548921
Regulatory RNAs in bacteriaQ24595082
Efficient translation of the RpoS sigma factor in Salmonella typhimurium requires host factor I, an RNA-binding protein encoded by the hfq geneQ24643457
DsrA RNA regulates translation of RpoS message by an anti-antisense mechanism, independent of its action as an antisilencer of transcriptionQ24645477
Riboregulation in Escherichia coli: DsrA RNA acts by RNA:RNA interactions at multiple lociQ24645507
A trans-acting RNA as a control switch in Escherichia coli: DsrA modulates function by forming alternative structuresQ24652762
Sm-like proteins in Eubacteria: the crystal structure of the Hfq protein from Escherichia coliQ27641658
Structure of Escherichia coli Hfq bound to polyriboadenylate RNAQ27658064
Global analysis of small RNA and mRNA targets of HfqQ28184898
Small non-coding RNAs, co-ordinators of adaptation processes in Escherichia coli: the RpoS paradigmQ28204689
Regulation of RpoS by a novel small RNA: the characterization of RprAQ28204998
Novel small RNA-encoding genes in the intergenic regions of Escherichia coliQ28205853
Regulation and mode of action of the second small RNA activator of RpoS translation, RprAQ28212671
The Sm-like Hfq protein increases OxyS RNA interaction with target mRNAsQ28216159
Signal transduction and regulatory mechanisms involved in control of the sigma(S) (RpoS) subunit of RNA polymeraseQ28220384
A genetic approach for finding small RNAs regulators of genes of interest identifies RybC as regulating the DpiA/DpiB two-component systemQ28244233
Base-pairing requirement for RNA silencing by a bacterial small RNA and acceleration of duplex formation by HfqQ28253347
Specific and pleiotropic patterns of mRNA regulation by ArcZ, a conserved, Hfq-dependent small RNAQ28257497
Translational activation of rpoS mRNA by the non-coding RNA DsrA and Hfq does not require ribosome bindingQ28266867
Remodelling of the Escherichia coli outer membrane by two small regulatory RNAsQ28287313
The rpoS mRNA leader recruits Hfq to facilitate annealing with DsrA sRNAQ28288672
Escherichia coli Hfq has distinct interaction surfaces for DsrA, rpoS and poly(A) RNAsQ28292183
Cycling of the Sm-like protein Hfq on the DsrA small regulatory RNAQ28294752
Effect of Hfq on RprA-rpoS mRNA pairing: Hfq-RNA binding and the influence of the 5' rpoS mRNA leader regionQ28295584
The small RNA regulators of Escherichia coli: roles and mechanisms*Q29618536
The bacterial Sm-like protein Hfq: a key player in RNA transactionsQ29620062
Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexesQ30461610
The OxyS regulatory RNA represses rpoS translation and binds the Hfq (HF-I) proteinQ33889724
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)9602-9607
P577publication date2010-05-10
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titlePositive regulation by small RNAs and the role of Hfq
P478volume107

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cites work (P2860)
Q55457570A Canonical Biophysical Model of the CsrA Global Regulator Suggests Flexible Regulator-Target Interactions.
Q40617343A computational strategy for the search of regulatory small RNAs in Actinobacillus pleuropneumoniae
Q28255704A conserved RpoS-dependent small RNA controls the synthesis of major porin OmpD
Q34680627A method for in vivo identification of bacterial small RNA-binding proteins
Q28546717A nitric oxide regulated small RNA controls expression of genes involved in redox homeostasis in Bacillus subtilis
Q42883177A small RNA activates CFA synthase by isoform-specific mRNA stabilization
Q41526489A small RNA serving both the Hfq and CsrA regulons
Q35854632A small RNA that regulates motility and biofilm formation in response to changes in nutrient availability in Escherichia coli.
Q35591154A small, microRNA-size, ribonucleic acid regulating gene expression and development of Shiga toxin-converting bacteriophage Φ24Β.
Q36219862Acidic Residues in the Hfq Chaperone Increase the Selectivity of sRNA Binding and Annealing
Q36172268Alternative Hfq-sRNA interaction modes dictate alternative mRNA recognition
Q33712153An upstream Hfq binding site in the fhlA mRNA leader region facilitates the OxyS-fhlA interaction
Q41639297Antibacterial activity of silver nanoparticles target sara through srna-teg49, a key mediator of hfq, in staphylococcus aureus
Q54350084Antitoxin DinJ influences the general stress response through transcript stabilizer CspE.
Q30418101Archaeal and eukaryotic homologs of Hfq: A structural and evolutionary perspective on Sm function
Q42753757Arginine Patch Predicts the RNA Annealing Activity of Hfq from Gram-Negative and Gram-Positive Bacteria
Q34606300Association of RNAs with Bacillus subtilis Hfq.
Q36400621Balancing gene expression without library construction via a reusable sRNA pool
Q34061171Base pairing small RNAs and their roles in global regulatory networks
Q41953572Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq.
Q42357060Classic Spotlight: Hfq, from a Specific Host Factor for Phage Replication to a Global Player in Riboregulation
Q34388505Comparative analysis of regulatory elements between Escherichia coli and Klebsiella pneumoniae by genome-wide transcription start site profiling
Q37122110Conserved arginines on the rim of Hfq catalyze base pair formation and exchange
Q42772740Contribution of Hfq to photooxidative stress resistance and global regulation in Rhodobacter sphaeroides
Q30252727Crystal structure and RNA-binding properties of an Hfq homolog from the deep-branching Aquificae: conservation of the lateral RNA-binding mode
Q38087172Cycling of RNAs on Hfq.
Q36280099De novo automated design of small RNA circuits for engineering synthetic riboregulation in living cells
Q34504665Differential expression of small RNAs under chemical stress and fed-batch fermentation in E. coli
Q34508819Disruption of small RNA signaling caused by competition for Hfq.
Q46276966DksA and ppGpp Regulate the σS Stress Response by Activating Promoters for the Small RNA DsrA and the Anti-Adapter Protein IraP.
Q38295541Domain swapping between homologous bacterial small RNAs dissects processing and Hfq binding determinants and uncovers an aptamer for conditional RNase E cleavage.
Q40736188DsrA regulatory RNA represses both hns and rbsD mRNAs through distinct mechanisms in Escherichia coli.
Q24567581Dual RNA regulatory control of a Staphylococcus aureus virulence factor
Q24607427Duplex formation between the sRNA DsrA and rpoS mRNA is not sufficient for efficient RpoS synthesis at low temperature
Q35088012Dynamic competition of DsrA and rpoS fragments for the proximal binding site of Hfq as a means for efficient annealing
Q99616572Early termination of the Shiga toxin transcript generates a regulatory small RNA
Q61449803Enteropathogens: Tuning Their Gene Expression for Hassle-Free Survival
Q52575121Enzymes Involved in Posttranscriptional RNA Metabolism in Gram-Negative Bacteria.
Q36740865Exploring sRNA-mediated gene silencing mechanisms using artificial small RNAs derived from a natural RNA scaffold in Escherichia coli.
Q40164975Expression of IroN, the salmochelin siderophore receptor, requires mRNA activation by RyhB small RNA homologues.
Q98192446Gene autoregulation by 3' UTR-derived bacterial small RNAs
Q28241086Genome-wide identification of Hfq-regulated small RNAs in the fire blight pathogen Erwinia amylovora discovered small RNAs with virulence regulatory function
Q28246632Global discovery of small RNAs in Yersinia pseudotuberculosis identifies Yersinia-specific small, noncoding RNAs required for virulence
Q39798384Global small RNA chaperone Hfq and regulatory small RNAs are important virulence regulators in Erwinia amylovora
Q35624257Global transcriptome analysis reveals small RNAs affecting Neisseria meningitidis bacteremia.
Q91935778Hfq Globally Binds and Destabilizes sRNAs and mRNAs in Yersinia pestis
Q50030594Hfq and Hfq-dependent small RNAs are major contributors to multicellular development in Salmonella enterica serovar Typhimurium
Q29615791Hfq and its constellation of RNA
Q51271782Hfq and three Hfq-dependent small regulatory RNAs-MgrR, RyhB and McaS-coregulate the locus of enterocyte effacement in enteropathogenic Escherichia coli.
Q37015883Hfq assists small RNAs in binding to the coding sequence of ompD mRNA and in rearranging its structure
Q28293533Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS
Q40987473Hfq binds directly to the ribosome-binding site of IS10 transposase mRNA to inhibit translation
Q27685299Hfq binds ribonucleotides in three different RNA-binding sites
Q57260318Hfq chaperone brings speed dating to bacterial sRNA
Q47104096Hfq links translation repression to stress-induced mutagenesis in E. coli
Q36280714Hfq proximity and orientation controls RNA annealing
Q42146755Hfq restructures RNA-IN and RNA-OUT and facilitates antisense pairing in the Tn10/IS10 system
Q27677477Hfq-bridged ternary complex is important for translation activation of rpoS by DsrA
Q34927627Honing the message: post-transcriptional and post-translational control in attaching and effacing pathogens
Q34103665Identification of sRNAs expressed by the human pathogen Neisseria gonorrhoeae under disparate growth conditions.
Q34740470Identifying and characterizing Hfq-RNA interactions
Q34026223In vivo mRNA profiling of uropathogenic Escherichia coli from diverse phylogroups reveals common and group-specific gene expression profiles
Q38141997Influence of small RNAs on biofilm formation process in bacteria.
Q40631587Inhibition of Phagocytic Killing of Escherichia coli in Drosophila Hemocytes by RNA Chaperone Hfq.
Q35190035Integrated stress responses in Salmonella
Q28289704Integrating anaerobic/aerobic sensing and the general stress response through the ArcZ small RNA
Q28583172In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways
Q35852136Isoenergetic microarrays to study the structure and interactions of DsrA and OxyS RNAs in two- and three-component complexes
Q34510047Large-scale mapping of sequence-function relations in small regulatory RNAs reveals plasticity and modularity
Q42174762Major role for mRNA binding and restructuring in sRNA recruitment by Hfq.
Q27680705Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching
Q90271711Mechanism for coordinate regulation of rpoS by sRNA-sRNA interaction in Escherichia coli
Q64928887Mechanisms for Hfq-Independent Activation of rpoS by DsrA, a Small RNA, in Escherichia coli.
Q34811166Modification of the RpoS network with a synthetic small RNA.
Q40280690Molecular mechanism of mRNA repression in trans by a ProQ-dependent small RNA.
Q34322538Mutations in interaction surfaces differentially impact E. coli Hfq association with small RNAs and their mRNA targets
Q38199289Ménage à trois: post-transcriptional control of the key enzyme for cell envelope synthesis by a base-pairing small RNA, an RNase adaptor protein, and a small RNA mimic
Q50561896Natural RNA Polymerase Aptamers Regulate Transcription in E. coli.
Q36901756New developments in post-transcriptional regulation of operons by small RNAs
Q34271960Non-coding sRNAs regulate virulence in the bacterial pathogen Vibrio cholerae.
Q42291805Nucleoid and cytoplasmic localization of small RNAs in Escherichia coli.
Q89824505On a stake-out: Mycobacterial small RNA identification and regulation
Q38153167On the importance of cotranscriptional RNA structure formation
Q38935351Paradoxical suppression of small RNA activity at high Hfq concentrations due to random-order binding
Q33352676Pathway engineering via quorum sensing and sRNA riboregulators-interconnected networks and controllers
Q34056874Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile
Q35859490Polyamines Stimulate the Level of the σ38 Subunit (RpoS) of Escherichia coli RNA Polymerase, Resulting in the Induction of the Glutamate Decarboxylase-dependent Acid Response System via the gadE Regulon
Q34372359Positional effects of AAN motifs in rpoS regulation by sRNAs and Hfq.
Q37254225Post-transcriptional activation of a diguanylate cyclase by quorum sensing small RNAs promotes biofilm formation in Vibrio cholerae.
Q57344163Post-transcriptional gene regulation by an Hfq-independent small RNA in Caulobacter crescentus
Q90138932Prevalence of small base-pairing RNAs derived from diverse genomic loci
Q34526027Protection against deleterious nitrogen compounds: role of σS-dependent small RNAs encoded adjacent to sdiA.
Q35089000Protein mistranslation protects bacteria against oxidative stress
Q90560683Proteins That Chaperone RNA Regulation
Q28742043Quantifying the sequence-function relation in gene silencing by bacterial small RNAs
Q37806517RNA folding in living cells
Q38324094RNase footprinting of protein binding sites on an mRNA target of small RNAs
Q35088007Rapid binding and release of Hfq from ternary complexes during RNA annealing
Q27009044Regulation by small RNAs in bacteria: expanding frontiers
Q42713382Requirement of the CsdA DEAD-box helicase for low temperature riboregulation of rpoS mRNA
Q36228436Requirement of upstream Hfq-binding (ARN)x elements in glmS and the Hfq C-terminal region for GlmS upregulation by sRNAs GlmZ and GlmY.
Q34122762Revisiting the coding potential of the E. coli genome through Hfq co-immunoprecipitation
Q48058614Roles of Hfq in the stress adaptation and virulence in fish pathogen Vibrio alginolyticus and its potential application as a target for live attenuated vaccine
Q36709429Small RNA Regulation of TolC, the Outer Membrane Component of Bacterial Multidrug Transporters
Q37618005Small RNA interactome of pathogenic E. coli revealed through crosslinking of RNase E.
Q21131371Small RNA sX13: a multifaceted regulator of virulence in the plant pathogen Xanthomonas
Q36008348Small RNA-based feedforward loop with AND-gate logic regulates extrachromosomal DNA transfer in Salmonella
Q37878988Small RNAs as regulators of primary and secondary metabolism in Pseudomonas species
Q38230079Small RNAs in the control of RpoS, CsgD, and biofilm architecture of Escherichia coli
Q38084831Small Regulatory RNAs in the Control of Motility and Biofilm Formation in E. coli and Salmonella
Q93270719Stem-loops direct precise processing of 3' UTR-derived small RNA MicL
Q42324804Structural flexibility of RNA as molecular basis for Hfq chaperone function
Q35131127Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq.
Q27672887Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract
Q34661444Structural model of an mRNA in complex with the bacterial chaperone Hfq.
Q41430016Study of E. coli Hfq's RNA annealing acceleration and duplex destabilization activities using substrates with different GC-contents
Q57072123Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E
Q28081126Target activation by regulatory RNAs in bacteria
Q28286931Targeted decay of a regulatory small RNA by an adaptor protein for RNase E and counteraction by an anti-adaptor RNA
Q34428089The Listeria Small RNA Rli27 Regulates a Cell Wall Protein inside Eukaryotic Cells by Targeting a Long 5'-UTR Variant
Q37545684The MiaA tRNA modification enzyme is necessary for robust RpoS expression in Escherichia coli
Q54261857The Pseudomonas aeruginosa PrrF1 and PrrF2 Small Regulatory RNAs Promote 2-Alkyl-4-Quinolone Production through Redundant Regulation of the antR mRNA.
Q30470671The Pseudomonas aeruginosa transcriptome in planktonic cultures and static biofilms using RNA sequencing
Q48529084The RNA chaperone, Hfq, controls two luxR-type regulators and plays a key role in pathogenesis and production of antibiotics in Serratia sp. ATCC 39006.
Q34189650The RpoS-mediated general stress response in Escherichia coli
Q34026379The Vibrio cholerae quorum sensing response is mediated by Hfq-dependent sRNA/mRNA base pairing interactions.
Q90196530The bacterial endoribonuclease RNase E can cleave RNA in the absence of the RNA chaperone Hfq
Q37995707The bacterial protein Hfq: much more than a mere RNA-binding factor
Q42103322The crucial role of PNPase in the degradation of small RNAs that are not associated with Hfq.
Q24624170The group A Streptococcus small regulatory RNA FasX enhances streptokinase activity by increasing the stability of the ska mRNA transcript
Q26852007The interplay of Hfq, poly(A) polymerase I and exoribonucleases at the 3' ends of RNAs resulting from Rho-independent termination: A tentative model
Q37142772The novel regulatory ncRNA, NfiS, optimizes nitrogen fixation via base pairing with the nitrogenase gene nifK mRNA in Pseudomonas stutzeri A1501
Q35107832The phzA2-G2 transcript exhibits direct RsmA-mediated activation in Pseudomonas aeruginosa M18.
Q21131294The small RNA SgrS: roles in metabolism and pathogenesis of enteric bacteria
Q38647767The spectrum of activity of the small RNA DsrA: not so narrow after all.
Q90657919Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica
Q35987861Transcriptomic analysis of the stationary phase response regulator SpdR in Caulobacter crescentus
Q92732858Trouble is coming: Signaling pathways that regulate general stress responses in bacteria
Q94461584Tunable genetic devices through simultaneous control of transcription and translation
Q61806336sRNA Target Prediction Organizing Tool (SPOT) Integrates Computational and Experimental Data To Facilitate Functional Characterization of Bacterial Small RNAs
Q41207283sRNA-Mediated Control of Transcription Termination in E. coli
Q35751282sRNA-Mediated Regulation of P-Fimbriae Phase Variation in Uropathogenic Escherichia coli.
Q24597091sRNAs and the virulence of Salmonella enterica serovar Typhimurium

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